Gene/Proteome Database (LMPD)

LMPD ID
LMP007160
Gene ID
854965
Species
Saccharomyces cerevisiae S288c (Yeast (S288c))
Gene Name
carnitine O-acetyltransferase CAT2
Gene Symbol
CAT2
Synonyms
YCAT
Alternate Names
carnitine O-acetyltransferase CAT2
Chromosome
XIII
EC Number
2.3.1.7

Proteins

carnitine O-acetyltransferase CAT2
Refseq ID NP_013670
Protein GI 6323599
UniProt ID P32796
mRNA ID NM_001182400
Length 670
RefSeq Status PROVISIONAL
MRICHSRTLSNLKDLPITSRRAMHSAIVNYSTQKAQFPVETNNGEHYWAEKPNKFYQNKRPNFQGITFAKQQDLPSLPVPELKSTLDKYLQTIRPFCNDVETFERQQLLCKDFSEHMGPILQDRLKEYANDKRNWMAKFWDEQSYLQYNDPIVPYVSYFYSHMPLPNHLSKIDNDPLIKATAIISTVVKFIEAIKDESLPVEIIKGMPFCMNSFSLMFNTSRLPGKPEDNQDTNIFYSVYENNFVTIAYKGKFYKLMTHDGNDKPLSENEIWRQLYSVVFQGSQSDPKLGGIGSLTSLPRDQWREVHLELMKDPISQDSLETIHKSSFMLCLDLDQSPVTLEEKSRNCWHGDGINRFYDKSLQFLVTGNGSSGFLAEHSKMDGTPTLFLNNYVCQQLNKLDVDDFMRKVITPSSTVAMKPMELPFIITPKIHKAIESAQLQFKETIGEHDLRVWHYNKYGKTFIKRHGMSPDAFIQQVIQLAVFKYLKRQLPTYEAASTRKYFKGRTETGRSVSTASLEFVSKWQNGDVPIAEKIQALKHSAKEHSTYLKNAANGNGVDRHFFGLKNMLKSNDDQIPPLFKDPLFNYSSTWLISTSQLSSEYFDGYGWSQVNDNGFGLAYMLNNEWLHINIVNKPAKSGASVNRLHYYLSQAADEIFDALENENKRKAKL

Gene Information

Entrez Gene ID
854965
Gene Name
carnitine O-acetyltransferase CAT2
Gene Symbol
CAT2
Species
Saccharomyces cerevisiae S288c

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005743 IEA:UniProtKB-KW C mitochondrial inner membrane
GO:0005739 IDA:SGD C mitochondrion
GO:0005777 IDA:SGD C peroxisome
GO:0004092 IMP:SGD F carnitine O-acetyltransferase activity
GO:0009437 IMP:SGD P carnitine metabolic process
GO:0006631 IEA:UniProtKB-KW P fatty acid metabolic process
GO:0006810 IEA:UniProtKB-KW P transport

KEGG Pathway Links

KEGG Pathway ID Description
sce04146 Peroxisome

BIOCYC Pathway Links

BIOCYC Pathway ID Description
PWY3O-4 carnitine shuttle

REACTOME Pathway Links

REACTOME Pathway ID Description
5618483 Beta-oxidation of very long chain fatty acids
5618446 Synthesis of PC

Domain Information

InterPro Annotations

Accession Description
IPR000542 Acyltransferase ChoActase/COT/CPT

UniProt Annotations

Entry Information

Gene Name
carnitine O-acetyltransferase CAT2
Protein Entry
CACP_YEAST
UniProt ID
P32796
Species
Yeast (S288c)

Comments

Comment Type Description
Alternative Products Event=Alternative initiation; Named isoforms=2; Name=Mitochondrial; IsoId=P32796-1; Sequence=Displayed; Name=Peroxisomal; IsoId=P32796-2; Sequence=VSP_018690; Note=Produced by alternative initiation at Met-23 of isoform Mitochondrial.;
Catalytic Activity Acetyl-CoA + carnitine = CoA + O- acetylcarnitine.
Function Carnitine acetylase is specific for short chain fatty acids. Carnitine acetylase seems to affect the flux through the pyruvate dehydrogenase complex. It may be involved as well in the transport of acetyl-CoA into mitochondria.
Induction By ethanol. Repressed by galactose.
Interaction Self; NbExp=1; IntAct=EBI-3935, EBI-3935; Q07732:ADY3; NbExp=1; IntAct=EBI-3935, EBI-33406; Q02821:SRP1; NbExp=1; IntAct=EBI-3935, EBI-1797;
Miscellaneous Present with 450 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
Similarity Belongs to the carnitine/choline acetyltransferase family. {ECO:0000305}.
Subcellular Location Isoform Mitochondrial: Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Subcellular Location Isoform Peroxisomal: Peroxisome.

Identical and Related Proteins

Unique RefSeq proteins for LMP007160 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
6323599 RefSeq NP_013670 670 carnitine O-acetyltransferase CAT2

Identical Sequences to LMP007160 proteins

Reference Database Accession Length Protein Name
GI:6323599 DBBJ GAA25406.1 670 K7_Cat2p [Saccharomyces cerevisiae Kyokai no. 7]
GI:6323599 EMBL CAY04441.1 670 unnamed protein product [Saccharomyces cerevisiae]
GI:6323599 EMBL CBN63528.1 670 unnamed protein product [Saccharomyces cerevisiae]
GI:6323599 EMBL CBN60636.1 670 unnamed protein product [Saccharomyces cerevisiae]
GI:6323599 EMBL CBN65245.1 670 unnamed protein product [Saccharomyces cerevisiae]
GI:6323599 Third Party Genbank DAA09857.1 670 TPA: carnitine O-acetyltransferase CAT2 [Saccharomyces cerevisiae S288c]

Related Sequences to LMP007160 proteins

Reference Database Accession Length Protein Name
GI:6323599 EMBL CAA78399.1 670 carnitine acetyltransferase [Saccharomyces cerevisiae]
GI:6323599 GenBank EIW08642.1 670 Cat2p [Saccharomyces cerevisiae CEN.PK113-7D]
GI:6323599 GenBank EWG83892.1 670 Cat2p [Saccharomyces cerevisiae R008]
GI:6323599 GenBank EWG94311.1 670 Cat2p [Saccharomyces cerevisiae R103]
GI:6323599 GenBank EWH16596.1 670 Cat2p [Saccharomyces cerevisiae P283]
GI:6323599 gnl McCuskerlabDuke 670 Cat2p [Saccharomyces cerevisiae YJM993]