Gene/Proteome Database (LMPD)

LMPD ID
LMP007182
Gene ID
852835
Species
Saccharomyces cerevisiae S288c (Yeast (S288c))
Gene Name
N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase catalytic subunit ALG13
Gene Symbol
ALG13
Synonyms
-
Alternate Names
N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase catalytic subunit ALG13
Chromosome
VII
EC Number
2.4.1.141

Proteins

N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase catalytic subunit ALG13
Refseq ID NP_011468
Protein GI 6321391
UniProt ID P53178
mRNA ID NM_001180912
Length 202
RefSeq Status PROVISIONAL
MGIIEEKALFVTCGATVPFPKLVSCVLSDEFCQELIQYGFVRLIIQFGRNYSSEFEHLVQERGGQRESQKIPIDQFGCGDTARQYVLMNGKLKVIGFDFSTKMQSIIRDYSDLVISHAGTGSILDSLRLNKPLIVCVNDSLMDNHQQQIADKFVELGYVWSCAPTETGLIAGLRASQTEKLKPFPVSHNPSFERLLVETIYS

Gene Information

Entrez Gene ID
852835
Gene Name
N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase catalytic subunit ALG13
Gene Symbol
ALG13
Species
Saccharomyces cerevisiae S288c

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0043541 IPI:SGD C UDP-N-acetylglucosamine transferase complex
GO:0005737 IDA:SGD C cytoplasm
GO:0005829 IDA:SGD C cytosol
GO:0042406 IDA:SGD C extrinsic component of endoplasmic reticulum membrane
GO:0004577 IEA:UniProtKB-EC F N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity
GO:0030246 IEA:InterPro F carbohydrate binding
GO:0006488 IDA:SGD P dolichol-linked oligosaccharide biosynthetic process
GO:0030259 IEA:InterPro P lipid glycosylation

KEGG Pathway Links

KEGG Pathway ID Description
sce00510 N-Glycan biosynthesis
sce_M00055 N-glycan precursor biosynthesis
sce00513 Various types of N-glycan biosynthesis

BIOCYC Pathway Links

BIOCYC Pathway ID Description
MANNOSYL-CHITO-DOLICHOL-BIOSYNTHESIS dolichyl-diphosphooligosaccharide biosynthesis

Domain Information

InterPro Annotations

Accession Description
IPR007235 Glycosyl transferase, family 28, C-terminal

UniProt Annotations

Entry Information

Gene Name
N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase catalytic subunit ALG13
Protein Entry
ALG13_YEAST
UniProt ID
P53178
Species
Yeast (S288c)

Comments

Comment Type Description
Catalytic Activity UDP-N-acetyl-D-glucosamine + N-acetyl-D- glucosaminyl-diphosphodolichol = UDP + N,N'-diacetylchitobiosyl- diphosphodolichol.
Function Involved in protein N-glycosylation. Essential for the second step of the dolichol-linked oligosaccharide pathway. {ECO:0000269|PubMed:15615718, ECO:0000269|PubMed:16100110}.
Interaction P38242:ALG14; NbExp=3; IntAct=EBI-23770, EBI-21477;
Miscellaneous Present with 1950 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
Similarity Belongs to the glycosyltransferase 28 family. {ECO:0000305}.
Subcellular Location Endoplasmic reticulum {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:16100110}.
Subunit Heterodimer with ALG14 to form a functional enzyme.

Identical and Related Proteins

Unique RefSeq proteins for LMP007182 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
6321391 RefSeq NP_011468 202 N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase catalytic subunit ALG13

Identical Sequences to LMP007182 proteins

Reference Database Accession Length Protein Name
GI:6321391 EMBL CAA96749.1 202 unnamed protein product [Saccharomyces cerevisiae]
GI:6321391 GenBank EEU06394.1 202 Alg13p [Saccharomyces cerevisiae JAY291]
GI:6321391 GenBank EIW10307.1 202 Alg13p [Saccharomyces cerevisiae CEN.PK113-7D]
GI:6321391 SwissProt P53178.1 202 RecName: Full=UDP-N-acetylglucosamine transferase subunit ALG13; AltName: Full=Asparagine-linked glycosylation protein 13 [Saccharomyces cerevisiae S288c]
GI:6321391 Third Party Genbank DAA08054.1 202 TPA: N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase catalytic subunit ALG13 [Saccharomyces cerevisiae S288c]

Related Sequences to LMP007182 proteins

Reference Database Accession Length Protein Name
GI:6321391 EMBL CAY79713.1 202 Alg13p [Saccharomyces cerevisiae EC1118]
GI:6321391 GenBank EDV10277.1 202 UDP-N-acetylglucosamine transferase [Saccharomyces cerevisiae RM11-1a]
GI:6321391 GenBank EDZ72175.1 202 YGL047Wp-like protein [Saccharomyces cerevisiae AWRI1631]
GI:6321391 GenBank EWG90954.1 202 Alg13p [Saccharomyces cerevisiae P301]
GI:6321391 GenBank EWG96056.1 202 Alg13p [Saccharomyces cerevisiae R103]
GI:6321391 GenBank EWH18234.1 202 Alg13p [Saccharomyces cerevisiae P283]