Gene/Proteome Database (LMPD)
Proteins
sterol 24-C-methyltransferase | |
---|---|
Refseq ID | NP_013706 |
Protein GI | 6323635 |
UniProt ID | P25087 |
mRNA ID | NM_001182363 |
Length | 383 |
MSETELRKRQAQFTRELHGDDIGKKTGLSALMSKNNSAQKEAVQKYLRNWDGRTDKDAEERRLEDYNEATHSYYNVVTDFYEYGWGSSFHFSRFYKGESFAASIARHEHYLAYKAGIQRGDLVLDVGCGVGGPAREIARFTGCNVIGLNNNDYQIAKAKYYAKKYNLSDQMDFVKGDFMKMDFEENTFDKVYAIEATCHAPKLEGVYSEIYKVLKPGGTFAVYEWVMTDKYDENNPEHRKIAYEIELGDGIPKMFHVDVARKALKNCGFEVLVSEDLADNDDEIPWYYPLTGEWKYVQNLANLATFFRTSYLGRQFTTAMVTVMEKLGLAPEGSKEVTAALENAAVGLVAGGKSKLFTPMMLFVARKPENAETPSQTSQEATQ |
Gene Information
Entrez Gene ID
Gene Name
sterol 24-C-methyltransferase
Gene Symbol
Species
Saccharomyces cerevisiae S288c
Gene Ontology (GO Annotations)
GO ID | Source | Type | Description |
---|---|---|---|
GO:0005783 | IDA:SGD | C | endoplasmic reticulum |
GO:0005811 | IDA:SGD | C | lipid particle |
GO:0003838 | IDA:SGD | F | sterol 24-C-methyltransferase activity |
GO:0006696 | IMP:SGD | P | ergosterol biosynthetic process |
KEGG Pathway Links
KEGG Pathway ID | Description |
---|---|
sce01110 | Biosynthesis of secondary metabolites |
M00102 | Ergocalciferol biosynthesis |
sce_M00102 | Ergocalciferol biosynthesis |
sce01100 | Metabolic pathways |
ko00100 | Steroid biosynthesis |
sce00100 | Steroid biosynthesis |
BIOCYC Pathway Links
BIOCYC Pathway ID | Description |
---|---|
PWY-6075 | ergosterol biosynthesis |
PWY-6075 | ergosterol biosynthesis I |
ERGOSTEROL-SYN-PWY | superpathway of ergosterol biosynthesis |
ERGOSTEROL-SYN-PWY | superpathway of ergosterol biosynthesis I |
Domain Information
UniProt Annotations
Entry Information
Gene Name
sterol 24-C-methyltransferase
Protein Entry
ERG6_YEAST
UniProt ID
Species
Yeast (S288c)
Comments
Comment Type | Description |
---|---|
Catalytic Activity | S-adenosyl-L-methionine + 5-alpha-cholesta- 8,24-dien-3-beta-ol = S-adenosyl-L-homocysteine + 24-methylene-5- alpha-cholest-8-en-3-beta-ol. |
Function | Catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of zymosterol to form fecosterol. |
Interaction | Q12066:YDL089W; NbExp=1; IntAct=EBI-6567, EBI-35877; Q12274:YOR097C; NbExp=1; IntAct=EBI-6567, EBI-33978; |
Miscellaneous | Present with 53800 molecules/cell in log phase SD medium |
Miscellaneous | Present with 53800 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}. |
Pathway | Steroid metabolism; ergosterol biosynthesis; ergosterol from zymosterol: step 1/5. |
Similarity | Belongs to the class I-like SAM-binding methyltransferase superfamily. Erg6/SMT family |
Similarity | Belongs to the class I-like SAM-binding methyltransferase superfamily. Erg6/SMT family. {ECO:0000255|PROSITE-ProRule:PRU01022}. |
Subunit | Interacts with ERG28. {ECO:0000269|PubMed:15522820, ECO:0000269|PubMed:15995173}. |
Identical and Related Proteins
Unique RefSeq proteins for LMP007192 (as displayed in Record Overview)
Protein GI | Database | Accession | Length | Protein Name |
---|---|---|---|---|
6323635 | RefSeq | NP_013706 | 383 | sterol 24-C-methyltransferase |
Identical Sequences to LMP007192 proteins
Reference | Database | Accession | Length | Protein Name |
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Related Sequences to LMP007192 proteins
Reference | Database | Accession | Length | Protein Name |
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