Gene/Proteome Database (LMPD)
Proteins
| inositol monophosphate 1-phosphatase INM1 | |
|---|---|
| Refseq ID | NP_011912 |
| Protein GI | 6321836 |
| UniProt ID | P38710 |
| mRNA ID | NM_001179176 |
| Length | 295 |
| MTIDLASIEKFLCELATEKVGPIIKSKSGTQKDYDLKTGSRSVDIVTAIDKQVEKLIWESVKTQYPTFKFIGEESYVKGETVITDDPTFIIDPIDGTTNFVHDFPFSCTSLGLTVNKEPVVGVIYNPHINLLVSASKGNGMRVNNKDYDYKSKLESMGSLILNKSVVALQPGSAREGKNFQTKMATYEKLLSCDYGFVHGFRNLGSSAMTMAYIAMGYLDSYWDGGCYSWDVCAGWCILKEVGGRVVGANPGEWSIDVDNRTYLAVRGTINNESDEQTKYITDFWNCVDGHLKYD | |
Gene Information
Entrez Gene ID
Gene Name
inositol monophosphate 1-phosphatase INM1
Gene Symbol
Species
Saccharomyces cerevisiae S288c
Gene Ontology (GO Annotations)
| GO ID | Source | Type | Description |
|---|---|---|---|
| GO:0005737 | IEA:UniProtKB-KW | C | cytoplasm |
| GO:0005634 | IEA:UniProtKB-KW | C | nucleus |
| GO:0008934 | IDA:SGD | F | inositol monophosphate 1-phosphatase activity |
| GO:0052832 | IEA:UniProtKB-EC | F | inositol monophosphate 3-phosphatase activity |
| GO:0052833 | IEA:UniProtKB-EC | F | inositol monophosphate 4-phosphatase activity |
| GO:0046872 | IEA:UniProtKB-KW | F | metal ion binding |
| GO:0006021 | IEA:UniProtKB-UniPathway | P | inositol biosynthetic process |
| GO:0046855 | IDA:SGD | P | inositol phosphate dephosphorylation |
| GO:0046854 | IEA:InterPro | P | phosphatidylinositol phosphorylation |
KEGG Pathway Links
| KEGG Pathway ID | Description |
|---|---|
| sce01110 | Biosynthesis of secondary metabolites |
| ko00562 | Inositol phosphate metabolism |
| sce00562 | Inositol phosphate metabolism |
| sce01100 | Metabolic pathways |
| ko04070 | Phosphatidylinositol signaling system |
| sce04070 | Phosphatidylinositol signaling system |
BIOCYC Pathway Links
| BIOCYC Pathway ID | Description |
|---|---|
| PWY-2301 | myo-inositol biosynthesis |
REACTOME Pathway Links
Domain Information
UniProt Annotations
Entry Information
Gene Name
inositol monophosphate 1-phosphatase INM1
Protein Entry
INM1_YEAST
UniProt ID
Species
Yeast (S288c)
Comments
| Comment Type | Description |
|---|---|
| Biophysicochemical Properties | Kinetic parameters: KM=0.08 mM for inositol 1-phosphate {ECO:0000269|PubMed:10096091}; Vmax=20 umol/min/mg enzyme for inositol 1-phosphate {ECO:0000269|PubMed:10096091}; |
| Biophysicochemical Properties | Kinetic parameters: KM=0.08 mM for inositol 1-phosphate ; Vmax=20 umol/min/mg enzyme for inositol 1-phosphate ; |
| Catalytic Activity | Myo-inositol phosphate + H(2)O = myo-inositol + phosphate. |
| Cofactor | Name=Mg(2+); Xref=ChEBI:CHEBI:18420; |
| Enzyme Regulation | Inhibited by Li(+) and Na(+) |
| Enzyme Regulation | Inhibited by Li(+) and Na(+). {ECO:0000269|PubMed:10096091}. |
| Function | Responsible for the provision of inositol required for synthesis of phosphatidylinositol and polyphosphoinositides |
| Function | Responsible for the provision of inositol required for synthesis of phosphatidylinositol and polyphosphoinositides. {ECO:0000250}. |
| Miscellaneous | Present with 2440 molecules/cell in log phase SD medium |
| Miscellaneous | Present with 2440 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}. |
| Pathway | Polyol metabolism; myo-inositol biosynthesis; myo- inositol from D-glucose 6-phosphate: step 2/2. |
| Similarity | Belongs to the inositol monophosphatase family |
| Similarity | Belongs to the inositol monophosphatase family. {ECO:0000305}. |
| Subcellular Location | Cytoplasm . Nucleus . |
| Subcellular Location | Cytoplasm {ECO:0000269|PubMed:14562095}. Nucleus {ECO:0000269|PubMed:14562095}. |
Identical and Related Proteins
Unique RefSeq proteins for LMP007213 (as displayed in Record Overview)
| Protein GI | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| 6321836 | RefSeq | NP_011912 | 295 | inositol monophosphate 1-phosphatase INM1 |
Identical Sequences to LMP007213 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|
Related Sequences to LMP007213 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|