Gene/Proteome Database (LMPD)

LMPD ID
LMP007224
Gene ID
851508
Species
Saccharomyces cerevisiae S288c (Yeast (S288c))
Gene Name
1-acylglycerol-3-phosphate O-acyltransferase SLC1
Gene Symbol
SLC1
Synonyms
-
Alternate Names
1-acylglycerol-3-phosphate O-acyltransferase SLC1
Chromosome
IV
EC Number
2.3.1.51

Proteins

1-acylglycerol-3-phosphate O-acyltransferase SLC1
Refseq ID NP_010231
Protein GI 6320151
UniProt ID P33333
mRNA ID NM_001180111
Length 303
RefSeq Status PROVISIONAL
MSVIGRFLYYLRSVLVVLALAGCGFYGVIASILCTLIGKQHLAQWITARCFYHVMKLMLGLDVKVVGEENLAKKPYIMIANHQSTLDIFMLGRIFPPGCTVTAKKSLKYVPFLGWFMALSGTYFLDRSKRQEAIDTLNKGLENVKKNKRALWVFPEGTRSYTSELTMLPFKKGAFHLAQQGKIPIVPVVVSNTSTLVSPKYGVFNRGCMIVRILKPISTENLTKDKIGEFAEKVRDQMVDTLKEIGYSPAINDTTLPPQAIEYAALQHDKKVNKKIKNEPVPSVSISNDVNTHNEGSSVKKMH

Gene Information

Entrez Gene ID
851508
Gene Name
1-acylglycerol-3-phosphate O-acyltransferase SLC1
Gene Symbol
SLC1
Species
Saccharomyces cerevisiae S288c

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0005811 IDA:SGD C lipid particle
GO:0003841 IDA:SGD F 1-acylglycerol-3-phosphate O-acyltransferase activity
GO:0016024 IEA:UniProtKB-UniPathway P CDP-diacylglycerol biosynthetic process
GO:0046474 IGI:SGD P glycerophospholipid biosynthetic process

BIOCYC Pathway Links

BIOCYC Pathway ID Description
PWY-7417 phospholipid remodeling (phosphatidate)
PWY-7411 superpathway phosphatidate biosynthesis (yeast)

Domain Information

InterPro Annotations

Accession Description
IPR004552 1-acyl-sn-glycerol-3-phosphate acyltransferase
IPR002123 Phospholipid/glycerol acyltransferase

UniProt Annotations

Entry Information

Gene Name
1-acylglycerol-3-phosphate O-acyltransferase SLC1
Protein Entry
PLSC_YEAST
UniProt ID
P33333
Species
Yeast (S288c)

Comments

Comment Type Description
Catalytic Activity Acyl-CoA + 1-acyl-sn-glycerol 3-phosphate = CoA + 1,2-diacyl-sn-glycerol 3-phosphate.
Domain The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate. {ECO:0000250}.
Function May be an acyltransferase with an altered substrate specificity that enables it to use a C-26-CoA in place of the C-16 or C-18-CoAs used by the wild-type protein.
Interaction Q12168:ACF2; NbExp=1; IntAct=EBI-13494, EBI-32973; P25376:AGP1; NbExp=1; IntAct=EBI-13494, EBI-2357; P40471:AYR1; NbExp=1; IntAct=EBI-13494, EBI-25213; P08456:CHO1; NbExp=1; IntAct=EBI-13494, EBI-14055; P10614:ERG11; NbExp=1; IntAct=EBI-13494, EBI-5127; P38604:ERG7; NbExp=1; IntAct=EBI-13494, EBI-6572; P38225:FAT1; NbExp=1; IntAct=EBI-13494, EBI-6819; P19145:GAP1; NbExp=1; IntAct=EBI-13494, EBI-7314; P35844:KES1; NbExp=1; IntAct=EBI-13494, EBI-9648; P53224:ORM1; NbExp=1; IntAct=EBI-13494, EBI-12592; P41543:OST1; NbExp=1; IntAct=EBI-13494, EBI-12651; P25297:PHO84; NbExp=1; IntAct=EBI-13494, EBI-13320; P40975:PMP2; NbExp=1; IntAct=EBI-13494, EBI-2043041; P87284:PMP3; NbExp=1; IntAct=EBI-13494, EBI-13555; P35196:RER2; NbExp=1; IntAct=EBI-13494, EBI-14943; Q04947:RTN1; NbExp=1; IntAct=EBI-13494, EBI-38020; P32368:SAC1; NbExp=1; IntAct=EBI-13494, EBI-16210; P14359:SNA3; NbExp=1; IntAct=EBI-13494, EBI-26122; P39986:SPF1; NbExp=1; IntAct=EBI-13494, EBI-3128; P25037:UBP1; NbExp=1; IntAct=EBI-13494, EBI-19819; P28321:YJU3; NbExp=1; IntAct=EBI-13494, EBI-26790; P28625:YMR152W; NbExp=1; IntAct=EBI-13494, EBI-27313;
Pathway Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 2/3.
Similarity Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. {ECO:0000305}.
Subcellular Location Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.

Identical and Related Proteins

Unique RefSeq proteins for LMP007224 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
6320151 RefSeq NP_010231 303 1-acylglycerol-3-phosphate O-acyltransferase SLC1

Identical Sequences to LMP007224 proteins

Reference Database Accession Length Protein Name
GI:6320151 GenBank AFC05091.1 303 Sequence 42 from patent US 8110388
GI:6320151 GenBank EIW11157.1 303 Slc1p [Saccharomyces cerevisiae CEN.PK113-7D]
GI:6320151 GenBank AGO77842.1 303 Sequence 32 from patent US 8399226
GI:6320151 GenBank AGO77905.1 303 Sequence 152 from patent US 8399226
GI:6320151 GenBank AGV85561.1 303 Sequence 18 from patent US 8524485
GI:6320151 GenBank AGV85595.1 303 Sequence 97 from patent US 8524485

Related Sequences to LMP007224 proteins

Reference Database Accession Length Protein Name
GI:6320151 DBBJ GAA22194.1 303 K7_Slc1p [Saccharomyces cerevisiae Kyokai no. 7]
GI:6320151 EMBL CAY78456.1 303 Slc1p [Saccharomyces cerevisiae EC1118]
GI:6320151 GenBank EDZ73281.1 321 YDL052Cp-like protein, partial [Saccharomyces cerevisiae AWRI1631]
GI:6320151 GenBank EWG87024.1 303 Slc1p [Saccharomyces cerevisiae R008]
GI:6320151 GenBank EWG91734.1 303 Slc1p [Saccharomyces cerevisiae P301]
GI:6320151 GenBank EWG96946.1 303 Slc1p [Saccharomyces cerevisiae R103]