Gene/Proteome Database (LMPD)

LMPD ID
LMP007233
Gene ID
853830
Species
Saccharomyces cerevisiae S288c (Yeast (S288c))
Gene Name
UTP glucose-1-phosphate uridylyltransferase
Gene Symbol
UGP1
Synonyms
-
Chromosome
XI
EC Number
2.7.7.9

Proteins

UTP glucose-1-phosphate uridylyltransferase
Refseq ID NP_012889
Protein GI 398364619
UniProt ID P32861
mRNA ID NM_001179601
Length 499
MSTKKHTKTHSTYAFESNTNSVAASQMRNALNKLADSSKLDDAARAKFENELDSFFTLFRRYLVEKSSRTTLEWDKIKSPNPDEVVKYEIISQQPENVSNLSKLAVLKLNGGLGTSMGCVGPKSVIEVREGNTFLDLSVRQIEYLNRQYDSDVPLLLMNSFNTDKDTEHLIKKYSANRIRIRSFNQSRFPRVYKDSLLPVPTEYDSPLDAWYPPGHGDLFESLHVSGELDALIAQGREILFVSNGDNLGATVDLKILNHMIETGAEYIMELTDKTRADVKGGTLISYDGQVRLLEVAQVPKEHIDEFKNIRKFTNFNTNNLWINLKAVKRLIESSNLEMEIIPNQKTITRDGHEINVLQLETACGAAIRHFDGAHGVVVPRSRFLPVKTCSDLLLVKSDLFRLEHGSLKLDPSRFGPNPLIKLGSHFKKVSGFNARIPHIPKIVELDHLTITGNVFLGKDVTLRGTVIIVCSDGHKIDIPNGSILENVVVTGNLQILEH

Gene Information

Entrez Gene ID
853830
Gene Name
UTP glucose-1-phosphate uridylyltransferase
Gene Symbol
UGP1
Species
Saccharomyces cerevisiae S288c

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0003983 IMP:SGD F UTP:glucose-1-phosphate uridylyltransferase activity
GO:0046872 IEA:UniProtKB-KW F metal ion binding
GO:0070569 IDA:SGD F uridylyltransferase activity
GO:0006078 IMP:SGD P (1->6)-beta-D-glucan biosynthetic process
GO:0006011 IMP:SGD P UDP-glucose metabolic process
GO:0005978 IMP:SGD P glycogen biosynthetic process
GO:0005992 IGI:SGD P trehalose biosynthetic process

KEGG Pathway Links

KEGG Pathway ID Description
ko00520 Amino sugar and nucleotide sugar metabolism
sce00520 Amino sugar and nucleotide sugar metabolism
sce01110 Biosynthesis of secondary metabolites
ko00052 Galactose metabolism
sce00052 Galactose metabolism
sce01100 Metabolic pathways
M00549 Nucleotide sugar biosynthesis, glucose => UDP-glucose
sce_M00549 Nucleotide sugar biosynthesis, glucose => UDP-glucose
ko00040 Pentose and glucuronate interconversions
sce00040 Pentose and glucuronate interconversions
ko00500 Starch and sucrose metabolism
sce00500 Starch and sucrose metabolism

BIOCYC Pathway Links

BIOCYC Pathway ID Description
PWY-7343 UDP-glucose biosynthesis
PWY3O-1565 dolichyl glucosyl phosphate biosynthesis

REACTOME Pathway Links

REACTOME Pathway ID Description
5618031 Biological oxidations
5618026 Disease
5618028 Formation of the active cofactor, UDP-glucuronate
5618021 Glucose metabolism
5618029 Glucuronidation
5618025 Glycogen storage diseases
5618027 Glycogen synthesis
5618023 Metabolism
5618022 Metabolism of carbohydrates
5618024 Myoclonic epilepsy of Lafora
5618030 Phase II conjugation

Domain Information

InterPro Annotations

Accession Description
IPR029044 Nucleotide-diphospho-sugar transferases
IPR016267 UDPGP_trans
IPR002618 UTP--glucose-1-phosphate uridylyltransferase family

UniProt Annotations

Entry Information

Gene Name
UTP glucose-1-phosphate uridylyltransferase
Protein Entry
UGPA1_YEAST
UniProt ID
P32861
Species
Yeast (S288c)

Comments

Comment Type Description
Catalytic Activity UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose.
Function Plays a central role as a glucosyl donor in cellular metabolic pathways
Function Plays a central role as a glucosyl donor in cellular metabolic pathways. {ECO:0000269|PubMed:7588797}.
Interaction Q08217:PSK2; NbExp=3; IntAct=EBI-19987, EBI-9839;
Miscellaneous Present with 17200 molecules/cell in log phase SD medium
Miscellaneous Present with 17200 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
Similarity Belongs to the UDPGP type 1 family
Similarity Belongs to the UDPGP type 1 family. {ECO:0000305}.
Subunit Homooctamer
Subunit Homooctamer. {ECO:0000269|PubMed:17010990}.

Identical and Related Proteins

Unique RefSeq proteins for LMP007233 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
398364619 RefSeq NP_012889 499 UTP glucose-1-phosphate uridylyltransferase

Identical Sequences to LMP007233 proteins

Reference Database Accession Length Protein Name

Related Sequences to LMP007233 proteins

Reference Database Accession Length Protein Name