Gene/Proteome Database (LMPD)
Proteins
| Bet4p | |
|---|---|
| Refseq ID | NP_012503 |
| Protein GI | 41629687 |
| UniProt ID | Q00618 |
| mRNA ID | NM_001181465 |
| Length | 327 |
| RefSeq Status | PROVISIONAL |
| MHGIKRKQWTKELLRQKRVQDEKKIYDYRSLTENVLNMRDEKIYSIEALKKTSELLEKNPEFNAIWNYRRDIIASLASELEIPFWDKELVFVMMLLKDYPKVYWIWNHRLWVLKHYPTSSPKVWQTELAVVNKLLEQDARNYHGWHYRRIVVGNIESITNKSLDKEEFEYTTIKINNNISNYSAWHQRVQIISRMFQKGEVGNQKEYIRTEISYIINAMFTDAEDQSVWFYIKWFIKNDIVCKTLDEQEYLKMLKDLRENILLINNDEIEFSGKQNIWCLKILLVLEDILEEKEALTERSSEQYLVQLIDADPLRKNRYLHLLEQHK | |
Gene Information
Gene Ontology (GO Annotations)
| GO ID | Source | Type | Description |
|---|---|---|---|
| GO:0005968 | IDA:SGD | C | Rab-protein geranylgeranyltransferase complex |
| GO:0004663 | IDA:SGD | F | Rab geranylgeranyltransferase activity |
| GO:0017137 | ISS:UniProtKB | F | Rab GTPase binding |
| GO:0006888 | IMP:SGD | P | ER to Golgi vesicle-mediated transport |
| GO:0018344 | IDA:SGD | P | protein geranylgeranylation |
| GO:0006612 | IMP:SGD | P | protein targeting to membrane |
Domain Information
InterPro Annotations
| Accession | Description |
|---|---|
| IPR002088 | Protein prenyltransferase, alpha subunit |
UniProt Annotations
Entry Information
Comments
| Comment Type | Description |
|---|---|
| Catalytic Activity | Geranylgeranyl diphosphate + protein-cysteine = S-geranylgeranyl-protein + diphosphate. |
| Caution | Was originally thought to be MAD2. {ECO:0000305|PubMed:1651172}. |
| Function | Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to proteins having the C-terminal -XCC or -XCXC, where both cysteines may become modified. Acts on YPT1 and SEC4. |
| Interaction | P20133:BET2; NbExp=3; IntAct=EBI-3573, EBI-3559; |
| Sequence Caution | Sequence=AAA21386.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=CAA89323.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; |
| Similarity | Belongs to the protein prenyltransferase subunit alpha family. {ECO:0000305}. |
| Similarity | Contains 5 PFTA repeats. {ECO:0000255|PROSITE- ProRule:PRU00488}. |
| Subunit | Heterodimer of an alpha and a beta subunit. |
Identical and Related Proteins
Unique RefSeq proteins for LMP007240 (as displayed in Record Overview)
Identical Sequences to LMP007240 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:41629687 | GenBank | EWG85087.1 | 327 | Bet4p [Saccharomyces cerevisiae R008] |
| GI:41629687 | GenBank | EWG90366.1 | 327 | Bet4p [Saccharomyces cerevisiae P301] |
| GI:41629687 | GenBank | EWG95093.1 | 327 | Bet4p [Saccharomyces cerevisiae R103] |
| GI:41629687 | GenBank | EWH17840.1 | 327 | Bet4p [Saccharomyces cerevisiae P283] |
| GI:41629687 | gnl | McCuskerlabDuke | 327 | Bet4p [Saccharomyces cerevisiae YJM993] |
| GI:41629687 | Third Party Genbank | DAA08767.1 | 327 | TPA: Bet4p [Saccharomyces cerevisiae S288c] |
Related Sequences to LMP007240 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:41629687 | DBBJ | GAA24329.1 | 327 | K7_Bet4p [Saccharomyces cerevisiae Kyokai no. 7] |
| GI:41629687 | EMBL | CAA89323.1 | 290 | BET4 [Saccharomyces cerevisiae] |
| GI:41629687 | GenBank | AAA21386.1 | 290 | alpha subunit of type II geranylgeranyl transferase [Saccharomyces cerevisiae] |
| GI:41629687 | GenBank | EGA78356.1 | 290 | Bet4p [Saccharomyces cerevisiae Vin13] |
| GI:41629687 | GenBank | EGA86309.1 | 290 | Bet4p [Saccharomyces cerevisiae VL3] |
| GI:41629687 | GenBank | EIW09500.1 | 290 | Bet4p [Saccharomyces cerevisiae CEN.PK113-7D] |