Gene/Proteome Database (LMPD)

LMPD ID
LMP007291
Gene ID
853810
Species
Saccharomyces cerevisiae S288c (Yeast (S288c))
Gene Name
3-oxoacyl-[acyl-carrier-protein] reductase (NADPH)
Gene Symbol
OAR1
Synonyms
-
Alternate Names
3-oxoacyl-[acyl-carrier-protein] reductase (NADPH)
Chromosome
XI
EC Number
1.1.1.100

Proteins

3-oxoacyl-[acyl-carrier-protein] reductase (NADPH)
Refseq ID NP_012868
Protein GI 6322795
UniProt ID P35731
mRNA ID NM_001179621
Length 278
RefSeq Status PROVISIONAL
MHYLPVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEAKEMLERTIGASGTSAPAEIAEEVWSLYSRTALET

Gene Information

Entrez Gene ID
853810
Gene Name
3-oxoacyl-[acyl-carrier-protein] reductase (NADPH)
Gene Symbol
OAR1
Species
Saccharomyces cerevisiae S288c

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005739 IMP:SGD C mitochondrion
GO:0004316 IDA:SGD F 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
GO:0009060 IMP:SGD P aerobic respiration
GO:0006633 IEA:UniProtKB-UniPathway P fatty acid biosynthetic process
GO:0006631 IMP:SGD P fatty acid metabolic process

BIOCYC Pathway Links

BIOCYC Pathway ID Description
PWY-7388 octanoyl-ACP biosynthesis (mitochondria)

Domain Information

InterPro Annotations

Accession Description
IPR002347 Glucose/ribitol dehydrogenase
IPR016040 NAD(P)-binding domain
IPR002198 Short-chain dehydrogenase/reductase SDR
IPR020904 Short-chain dehydrogenase/reductase, conserved site

UniProt Annotations

Entry Information

Gene Name
3-oxoacyl-[acyl-carrier-protein] reductase (NADPH)
Protein Entry
FABG_YEAST
UniProt ID
P35731
Species
Yeast (S288c)

Comments

Comment Type Description
Catalytic Activity (3R)-3-hydroxyacyl-[acyl-carrier-protein] + NADP(+) = 3-oxoacyl-[acyl-carrier-protein] + NADPH.
Function Involved in biosynthesis of fatty acids in mitochondria. {ECO:0000250}.
Miscellaneous Present with 1760 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
Pathway Lipid metabolism; fatty acid biosynthesis.
Similarity Belongs to the short-chain dehydrogenases/reductases (SDR) family. {ECO:0000305}.
Subcellular Location Mitochondrion {ECO:0000269|PubMed:14562095}.

Identical and Related Proteins

Unique RefSeq proteins for LMP007291 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
6322795 RefSeq NP_012868 278 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH)

Identical Sequences to LMP007291 proteins

Reference Database Accession Length Protein Name
GI:6322795 GenBank EHN06131.1 278 Oar1p [Saccharomyces cerevisiae x Saccharomyces kudriavzevii VIN7]
GI:6322795 GenBank EIW09181.1 278 Oar1p [Saccharomyces cerevisiae CEN.PK113-7D]
GI:6322795 GenBank EWG84794.1 278 Oar1p [Saccharomyces cerevisiae R008]
GI:6322795 GenBank EWG90096.1 278 Oar1p [Saccharomyces cerevisiae P301]
GI:6322795 GenBank EWH17325.1 278 Oar1p [Saccharomyces cerevisiae P283]
GI:6322795 gnl McCuskerlabDuke 278 Oar1p [Saccharomyces cerevisiae YJM993]

Related Sequences to LMP007291 proteins

Reference Database Accession Length Protein Name
GI:6322795 PDB 4FD3 286 Chain B, Crystal Structure Of Apo-formed Ymtoar1
GI:6322795 PDB 4FD3 286 Chain C, Crystal Structure Of Apo-formed Ymtoar1
GI:6322795 PDB 4FD3 286 Chain D, Crystal Structure Of Apo-formed Ymtoar1
GI:6322795 PDB 4FD3 286 Chain E, Crystal Structure Of Apo-formed Ymtoar1
GI:6322795 PDB 4FD3 286 Chain F, Crystal Structure Of Apo-formed Ymtoar1
GI:6322795 PDB 4HBG 286 Chain A, Crystal Structure Of Saccharomyces Cerevisiae 3 Oxoacyl-[acyl Carrier Protein]-reductase Complexed With Nadph (form2)