Gene/Proteome Database (LMPD)

LMPD ID
LMP007308
Gene ID
851086
Species
Saccharomyces cerevisiae S288c (Yeast (S288c))
Gene Name
Rom2p
Gene Symbol
ROM2
Synonyms
-
Chromosome
XII

Proteins

Rom2p
Refseq ID NP_013475
Protein GI 6323403
UniProt ID P51862
mRNA ID NM_001182260
Length 1356
MSETNVDSLGDRNDIYSQIFGVERRPDSFATFDSDSHGDISSQLLPNRIENIQNLNVLLSEDIANDIIIAKQRRRSGVEAAIDDSDIPNNEMKGKSSNYILSQQTNIKEVPDTQSLSSADNTPVSSPKKARDATSSHPIVHAKSMSHIYSTSNSASRQAKHYNDHPLPPMSPRNEVYQKNKSTTAFVPKRKPSLPQLALAGLKKQSSFSTGSASTTPTQARKSPLQGFGFFSRPSSKDLHEQHQHHQHIQHNNINNHNNNNTNNNGAHYQVGSSNSNYPQHSHSISSRSMSLNSSTLKNIASSFQSKTSNSRKATQKYDITSNPFSDPHHHHHHHHSSNSHSSLNNVHGSGNSSSVMGSSSNIGLGLKTRVSSTSLALKRYTSVSGTSLSSPRRSSMTPLSASRPVMSASSKKPQVYPALLSRVATKFKSSIQLGEHKKDGLVYRDAFTGQQAVDVICAIIRTSDRNLALLFGRSLDAQKLFHDVVYEHRLRDSPHEVYEFTDNSRFTGTGSTNAHDPLMLLPNSSSFNSGNHSYPNSGMVPSSSTSSLNSDQATLTGSRLHMSSSLSQQKNPAAIHNVNGVFTLLAECYSPTCTRDALCYSISCPRRLEQQARLNLKPNGGLKRNISMALDDDDEEKPSWTSSVSKEDWENLPKKEIKRQEAIYEVYITEKNFVKSLEITRDTFMKTLAETNIISADIRKNFIKHVFAHINDIYSVNRRFLKALTDRQRSSPVVRGIGDIVLRFIPFFEPFVSYVASRPYAKYLIETQRSVNPYFARFDDDMMSSSLRHGIDSFLSQGVSRPGRYMLLVKEIMKSTDPEKDKSDYEDLSKAMDALRDFMKRIDQASGAAQDRHDVKLLKQKILFKNEYVNLGLNDERRKIKHEGILSRKELSKSDGTVVGDIQFYLLDNMLLFLKAKAVNKWHQHKVFQRPIPLPLLFACPGEDMPALRKYIGDHPDCSGTVIQPEYNTSNPKNAITFLYYGAKQRYQVTLYAAQYAGLQTLLEKIKQGQAAIISKTEMFNVTKMSDRFFDYTNKINSVTSCDGGRKLLIATNSGLYMSNIKRQQNKDHRHKSSAFFSTPIQLVQRNNITQIAVLEEFKSIILLIDKKLYSCPLSLIEAEGNGTSFFKKHHKELINHVSFFAEGDCNGKRLIVTAHSSSHSIKYFEHEHPLLAEKNGSGSGNKKSLKKKITEVIFDSEPVSISFLKANLCIGCKKGFQIVSISQNAHESLLDPADTSLEFALRDTLKPMAIYRVGNMFLLCYTEFAFFVNNQGWRKKESHIIHWEGEPQKFAIWYPYILAFDSNFIEIRKIETGELIRCVLADKIRLLQTSTQEILYCYEDYRGYDTVASLDFWG

Gene Information

Entrez Gene ID
851086
Gene Name
Rom2p
Gene Symbol
ROM2
Species
Saccharomyces cerevisiae S288c

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005934 IDA:SGD C cellular bud tip
GO:0000131 IDA:SGD C incipient cellular bud site
GO:0043332 IDA:SGD C mating projection tip
GO:0005089 IDA:SGD F Rho guanyl-nucleotide exchange factor activity
GO:0005546 IDA:SGD F phosphatidylinositol-4,5-bisphosphate binding
GO:0004871 IGI:SGD F signal transducer activity
GO:0005083 IEA:InterPro F small GTPase regulator activity
GO:0032862 IDA:SGD P activation of Rho GTPase activity
GO:0030010 IMP:SGD P establishment of cell polarity
GO:0043951 IMP:SGD P negative regulation of cAMP-mediated signaling
GO:0045807 IMP:SGD P positive regulation of endocytosis
GO:0060237 IGI:SGD P regulation of fungal-type cell wall organization
GO:0007264 IPI:SGD P small GTPase mediated signal transduction

REACTOME Pathway Links

REACTOME Pathway ID Description
5618500 G alpha (12/13) signalling events
5618409 GPCR downstream signaling
5618363 Rho GTPase cycle
5618100 Signal Transduction
5618180 Signaling by GPCR
5618364 Signaling by Rho GTPases

Domain Information

InterPro Annotations

Accession Description
IPR001180 Citron
IPR000591 DEP domain
IPR000219 Dbl homology (DH) domain
IPR011991 Winged helix-turn-helix DNA-binding domain

UniProt Annotations

Entry Information

Gene Name
Rom2p
Protein Entry
ROM2_YEAST
UniProt ID
P51862
Species
Yeast (S288c)

Comments

Comment Type Description
Function Stimulates the exchange of RHO1 GDP-bound form into GTP- bound form.
Similarity Contains 1 CNH domain. {ECO:0000255|PROSITE- ProRule:PRU00795}.
Similarity Contains 1 DH (DBL-homology) domain
Similarity Contains 1 DH (DBL-homology) domain. {ECO:0000255|PROSITE-ProRule:PRU00062}.

Identical and Related Proteins

Unique RefSeq proteins for LMP007308 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
6323403 RefSeq NP_013475 1356 Rom2p

Identical Sequences to LMP007308 proteins

Reference Database Accession Length Protein Name

Related Sequences to LMP007308 proteins

Reference Database Accession Length Protein Name