Gene/Proteome Database (LMPD)

LMPD ID
LMP007312
Gene ID
856472
Species
Saccharomyces cerevisiae S288c (Yeast (S288c))
Gene Name
oxysterol-binding protein related protein OSH3
Gene Symbol
OSH3
Synonyms
-
Alternate Names
oxysterol-binding protein related protein OSH3
Chromosome
VIII

Proteins

oxysterol-binding protein related protein OSH3
Refseq ID NP_011940
Protein GI 6321864
UniProt ID P38713
mRNA ID NM_001179203
Length 996
RefSeq Status PROVISIONAL
METIDIQNRSFVVRWVKCGRGDVINYQIKPLKKSIEVGIYKKLKSSVDDHASAVHIAPDTKTLLDYTTKSLLHKGSSSNIEEHHRRSSQHSHSSSNGSDNKRKERSYSSLSISGIQQQSQEIPLREKLSASGFTLVKRVGNVSGNTMVQGDLEVKDTDYYYAFILDNSSSKNAKKKILFNASVINGDNQSMISTRSTPPARPTALSRTSTQQDMLFRVGQGRYLQGYLLKKRRKRLQGFKKRFFTLDFRYGTLSYYLNDHNQTCRGEIVISLSSVSANKKDKIIIIDSGMEVWVLKATTKENWQSWVDALQTCFDDQFEDKDTSTLEENPDILDDDKEVINKSSPQDHDHLTPTATTKSALSHRQHTQKDMDDIYVPLPSESYATFSMNLRLIQQRLEQCKKDSLSYKPTTLHQRSEGLNGTHSSSSVFTNNRVSSFNHSSSGMTSSDSLASEEVPSNKTYIEHALYNQLADLEVFVSRFVTQGEVLFKDHQILCKKAKDTRVSLTSYLSENDEFFDAEEEISRGVIILPDTEDDINNIVEETPLLGKSDQNEFTKEVQLSGSEQIASSSVESYTTNDENHSRKHLKNRHKNRRRGHPHHQKTKSAQSSTETFTSKDLFALSYPKSVTRRNDIPEAAASPPSLLSFLRKNVGKDLSSIAMPVTSNEPISILQLISETFEYAPLLTKATQRPDPITFVSAFAISFLSIYRDKTRTLRKPFNPLLAETFELIREDMGFRLISEKVSHRPPVFAFFAEHLDWECSYTVTPSQKFWGKSIELNNEGILRLKFKTTGELFEWTQPTTILKNLIAGERYMEPVNEFEVHSSKGDKSHILFDKAGMFSGRSEGFKVSIIPPPSSNRKKETLAGKWTQSLANETTHETIWEVGDLVSNPKKKYGFTKFTANLNEITEIEKGNLPPTDSRLRPDIRAYEEGNVDKAEEWKLKLEQLQRERRNKGQDVEPKYFEKVSKNEWKYITGPKSYWERRKKHDWSDISQLW

Gene Information

Entrez Gene ID
856472
Gene Name
oxysterol-binding protein related protein OSH3
Gene Symbol
OSH3
Species
Saccharomyces cerevisiae S288c

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0032541 IDA:SGD C cortical endoplasmic reticulum
GO:0005737 IDA:SGD C cytoplasm
GO:0016021 IEA:InterPro C integral component of membrane
GO:0005545 ISS:SGD F 1-phosphatidylinositol binding
GO:0008289 IDA:SGD F lipid binding
GO:0008142 ISS:SGD F oxysterol binding
GO:0015248 IDA:SGD F sterol transporter activity
GO:0035621 IMP:SGD P ER to Golgi ceramide transport
GO:0006897 IGI:SGD P endocytosis
GO:0006887 IGI:SGD P exocytosis
GO:0001403 IGI:SGD P invasive growth in response to glucose limitation
GO:0000742 IGI:SGD P karyogamy involved in conjugation with cellular fusion
GO:0030011 IGI:SGD P maintenance of cell polarity
GO:0010922 IDA:SGD P positive regulation of phosphatase activity
GO:0007124 IMP:SGD P pseudohyphal growth
GO:0015918 IDA:SGD P sterol transport

Domain Information

InterPro Annotations

Accession Description
IPR009038 GOLD
IPR000648 Oxysterol-binding protein
IPR018494 Oxysterol-binding protein, conserved site
IPR001849 Pleckstrin homology domain
IPR011993 Pleckstrin homology-like domain

UniProt Annotations

Entry Information

Gene Name
oxysterol-binding protein related protein OSH3
Protein Entry
OSH3_YEAST
UniProt ID
P38713
Species
Yeast (S288c)

Comments

Comment Type Description
Domain The FFAT motif is required for interaction with SCS2 and proper localization of the protein. {ECO:0000269|PubMed:12727870}.
Interaction P45818:ROK1; NbExp=3; IntAct=EBI-12630, EBI-15686; P32368:SAC1; NbExp=2; IntAct=EBI-12630, EBI-16210;
Miscellaneous Present with 589 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
Similarity Belongs to the OSBP family. {ECO:0000305}.
Similarity Contains 1 PH domain. {ECO:0000255|PROSITE- ProRule:PRU00145}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:11408574, ECO:0000269|PubMed:12727870}. Note=Enriched at the cell periphery in a SCS2-dependent manner.

Identical and Related Proteins

Unique RefSeq proteins for LMP007312 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
6321864 RefSeq NP_011940 996 oxysterol-binding protein related protein OSH3

Identical Sequences to LMP007312 proteins

Reference Database Accession Length Protein Name
GI:6321864 GenBank EGA78547.1 996 Osh3p [Saccharomyces cerevisiae Vin13]
GI:6321864 GenBank EHN06698.1 996 Osh3p [Saccharomyces cerevisiae x Saccharomyces kudriavzevii VIN7]
GI:6321864 GenBank EIW09972.1 996 Osh3p [Saccharomyces cerevisiae CEN.PK113-7D]
GI:6321864 GenBank EWG85721.1 996 Osh3p [Saccharomyces cerevisiae R008]
GI:6321864 GenBank EWG90654.1 996 Osh3p [Saccharomyces cerevisiae P301]
GI:6321864 GenBank EWG95692.1 996 Osh3p [Saccharomyces cerevisiae R103]

Related Sequences to LMP007312 proteins

Reference Database Accession Length Protein Name
GI:6321864 DBBJ GAA23789.1 996 K7_Osh3p [Saccharomyces cerevisiae Kyokai no. 7]
GI:6321864 GenBank EDV09122.1 996 conserved hypothetical protein [Saccharomyces cerevisiae RM11-1a]
GI:6321864 GenBank EGA82491.1 996 Osh3p [Saccharomyces cerevisiae Lalvin QA23]
GI:6321864 GenBank EHN02090.1 994 Osh3p [Saccharomyces cerevisiae x Saccharomyces kudriavzevii VIN7]
GI:6321864 GenBank EJT42386.1 994 OSH3-like protein [Saccharomyces kudriavzevii IFO 1802]
GI:6321864 gnl McCuskerlabDuke 996 Osh3p [Saccharomyces cerevisiae YJM993]