LIPID MAPS

LMPD ID

LMP007316

Gene ID

Species

Saccharomyces cerevisiae S288c (Yeast (S288c))

Gene Name

Exo70p

Gene Symbol

EXO70

Synonyms

-

Chromosome

X

Exo70p
Refseq ID	NP_012450
Protein GI	6322375
UniProt ID	P19658
mRNA ID	NM_001181518
Length	623
MPAEIDIDEADVLVLSQELQKTSKLTFEINKSLKKIAATSNQSSQLFTPILARNNVLTTLQRNIESTLNSVASVKDLANEASKYEIILQKGINQVGLKQYTQVVHKLDDMLEDIQSGQANREENSEFHGILTHLEQLIKRSEAQLRVYFISILNSIKPFDPQINITKKMPFPYYEDQQLGALSWILDYFHGNSEGSIIQDILVGERSKLILKCMAFLEPFAKEISTAKNAPYEKGSSGMNSYTEALLGFIANEKSLVDDLYSQYTESKPHVLSQILSPLISAYAKLFGANLKIVRSNLENFGFFSFELVESINDVKKSLRGKELQNYNLLQDCTQEVRQVTQSLFRDAIDRIIKKANSISTIPSNNGVTEATVDTMSRLRKFSEYKNGCLGAMDNITRENWLPSNYKEKEYTLQNEALNWEDHNVLLSCFISDCIDTLAVNLERKAQIALMPNQEPDVANPNSSKNKHKQRIGFFILMNLTLVEQIVEKSELNLMLAGEGHSRLERLKKRYISYMVSDWRDLTANLMDSVFIDSSGKKSKDKEQIKEKFRKFNEGFEDLVSKTKQYKLSDPSLKVTLKSEIISLVMPMYERFYSRYKDSFKNPRKHIKYTPDELTTVLNQLVR

Entrez Gene ID

Gene Name

Exo70p

Gene Symbol

EXO70

Species

Saccharomyces cerevisiae S288c

GO ID	Source	Type	Description
GO:0005935	IDA:SGD	C	cellular bud neck
GO:0005934	IDA:SGD	C	cellular bud tip
GO:0000145	IDA:SGD	C	exocyst
GO:0000131	IDA:SGD	C	incipient cellular bud site
GO:0005886	IDA:SGD	C	plasma membrane
GO:0017049	IDA:SGD	F	GTP-Rho binding
GO:0005546	IDA:SGD	F	phosphatidylinositol-4,5-bisphosphate binding
GO:0001927	IMP:SGD	P	exocyst assembly
GO:0051601	IGI:SGD	P	exocyst localization
GO:0006887	IMP:SGD	P	exocytosis
GO:0006893	IMP:SGD	P	Golgi to plasma membrane transport
GO:0015031	IEA:UniProtKB-KW	P	protein transport
GO:0007266	IDA:SGD	P	Rho protein signal transduction
GO:0090522	IC:SGD	P	vesicle tethering involved in exocytosis

Accession	Description
IPR016159	Cullin repeat-like-containing domain
IPR004140	Exo70

Gene Name

Exo70p

Protein Entry

EXO70_YEAST

UniProt ID

Species

Yeast (S288c)

Comment Type	Description
Function	Involved in the secretory pathway as part of the exocyst complex which tethers secretory vesicles to the sites of exocytosis. Plays a role in the assembly of the exocyst
Function	Involved in the secretory pathway as part of the exocyst complex which tethers secretory vesicles to the sites of exocytosis. Plays a role in the assembly of the exocyst. {ECO:0000269\|PubMed:15583030}.
Interaction	Q00245:RHO3; NbExp=3; IntAct=EBI-6717, EBI-15138;
Miscellaneous	Present with 4280 molecules/cell in log phase SD medium
Miscellaneous	Present with 4280 molecules/cell in log phase SD medium. {ECO:0000269\|PubMed:14562106}.
Similarity	Belongs to the EXO70 family
Similarity	Belongs to the EXO70 family. {ECO:0000305}.
Subcellular Location	Bud. Bud neck. Note=Its polarization in the cell depends on EXO84.
Subunit	The exocyst complex is composed of SEC3, SEC5, SEC6, SEC8, SEC10, SEC15, EXO70 and EXO84. Interacts with RHO3. {ECO:0000269\|PubMed:10207081, ECO:0000269\|PubMed:16249794, ECO:0000269\|PubMed:8978675}.