Gene/Proteome Database (LMPD)

LMPD ID
LMP007318
Gene ID
855895
Species
Saccharomyces cerevisiae S288c (Yeast (S288c))
Gene Name
Pgc1p
Gene Symbol
PGC1
Synonyms
-
Alternate Names
Pgc1p
Chromosome
XVI
EC Number
3.1.4.-

Proteins

Pgc1p
Refseq ID NP_015118
Protein GI 6325050
UniProt ID Q08959
mRNA ID NM_001184020
Length 321
RefSeq Status PROVISIONAL
MVEIVGHRAFKARYPENTLLAFEKAYAAGADVIETDLQMTSDGMVVVNHDSDTGRMWDKNLVIGESTWEEVKRLRCKEDGSLAMMTLKEILTWAVCHPGAKLMLDIKFTNEKIIMIKTFVIMLEVKNDLKFWQERITWGLWLLDWYDFGIETGVLKDFKVIVISLSLDIASQFVKRSLTLNDPHYKLFGISVHFVSSWTSQFRLRLLPVLMKNDIKVYLWTVNKPIDFKYLCELPIHGAITDDPIKARKLCDGHTVAKKPTAEKKFVAPSLASVDGLRFHAFIKVYNILCTLLYSKWVHIKLCGWSIAYVIFLFLRTIHFL

Gene Information

Entrez Gene ID
855895
Gene Name
Pgc1p
Gene Symbol
PGC1
Species
Saccharomyces cerevisiae S288c

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0005811 IDA:SGD C lipid particle
GO:0005739 IDA:SGD C mitochondrion
GO:0008889 IEA:InterPro F glycerophosphodiester phosphodiesterase activity
GO:0034479 IDA:SGD F phosphatidylglycerol phospholipase C activity
GO:0006071 IEA:InterPro P glycerol metabolic process
GO:0046475 IMP:SGD P glycerophospholipid catabolic process
GO:0034478 IMP:SGD P phosphatidylglycerol catabolic process

KEGG Pathway Links

KEGG Pathway ID Description
ko00564 Glycerophospholipid metabolism
sce00564 Glycerophospholipid metabolism

BIOCYC Pathway Links

BIOCYC Pathway ID Description
PWY-7366 phosphatidylglycerol degradation
PWY-7366 phosphatidylglycerol degradation

Domain Information

InterPro Annotations

Accession Description
IPR004129 Glycerophosphoryl diester phosphodiesterase
IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain

UniProt Annotations

Entry Information

Gene Name
Pgc1p
Protein Entry
PGC1_YEAST
UniProt ID
Q08959
Species
Yeast (S288c)

Comments

Comment Type Description
Disruption Phenotype Leads to the accumulation of phosphatidyl glycerol. {ECO:0000269|PubMed:18434318}.
Function Phosphatidylglycerol phospholipase required for the removal of excess phosphatidylglycerol (PG) via a phospholipase C- type degradation mechanism. {ECO:0000269|PubMed:16172116, ECO:0000269|PubMed:18434318}.
Miscellaneous Present with 3270 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
Similarity Belongs to the glycerophosphoryl diester phosphodiesterase family. {ECO:0000305}.
Similarity Contains 1 GP-PDE domain. {ECO:0000305}.
Subcellular Location Mitochondrion membrane {ECO:0000269|PubMed:12514182, ECO:0000269|PubMed:14576278, ECO:0000269|PubMed:16823961, ECO:0000269|PubMed:18434318}; Single- pass type IV membrane protein {ECO:0000269|PubMed:12514182, ECO:0000269|PubMed:14576278, ECO:0000269|PubMed:16823961, ECO:0000269|PubMed:18434318}.

Identical and Related Proteins

Unique RefSeq proteins for LMP007318 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
6325050 RefSeq NP_015118 321 Pgc1p

Identical Sequences to LMP007318 proteins

Reference Database Accession Length Protein Name
GI:6325050 GenBank EGA76568.1 321 Pgc1p [Saccharomyces cerevisiae Vin13]
GI:6325050 GenBank EGA80405.1 321 Pgc1p [Saccharomyces cerevisiae Lalvin QA23]
GI:6325050 GenBank EHN04246.1 321 Pgc1p [Saccharomyces cerevisiae x Saccharomyces kudriavzevii VIN7]
GI:6325050 GenBank EIW07332.1 321 Pgc1p [Saccharomyces cerevisiae CEN.PK113-7D]
GI:6325050 GenBank EWG93109.1 321 hypothetical protein R103_P20321 [Saccharomyces cerevisiae R103]
GI:6325050 gnl McCuskerlabDuke 321 Pgc1p [Saccharomyces cerevisiae YJM993]

Related Sequences to LMP007318 proteins

Reference Database Accession Length Protein Name
GI:6325050 DBBJ GAA26772.1 321 K7_Ypl206cp [Saccharomyces cerevisiae Kyokai no. 7]
GI:6325050 GenBank EGA60220.1 328 Pgc1p [Saccharomyces cerevisiae FostersO]
GI:6325050 GenBank EGA72563.1 286 Pgc1p [Saccharomyces cerevisiae AWRI796]
GI:6325050 GenBank EGA84482.1 326 Pgc1p [Saccharomyces cerevisiae VL3]
GI:6325050 GenBank EHM99979.1 334 Pgc1p [Saccharomyces cerevisiae x Saccharomyces kudriavzevii VIN7]
GI:6325050 GenBank EJS41461.1 321 YPL206C [Saccharomyces arboricola H-6]