Gene/Proteome Database (LMPD)
Proteins
| Ant1p | |
|---|---|
| Refseq ID | NP_015453 |
| Protein GI | 6325385 |
| UniProt ID | Q06497 |
| mRNA ID | NM_001184225 |
| Length | 328 |
| RefSeq Status | PROVISIONAL |
| MLTLESALTGAVASAMANIAVYPLDLSKTIIQSQVSPSSSEDSNEGKVLPNRRYKNVVDCMINIFKEKGILGLYQGMTVTTVATFVQNFVYFFWYTFIRKSYMKHKLLGLQSLKNRDGPITPSTIEELVLGVAAASISQLFTSPMAVVATRQQTVHSAESAKFTNVIKDIYRENNGDITAFWKGLRTGLALTINPSITYASFQRLKEVFFHDHSNDAGSLSAVQNFILGVLSKMISTLVTQPLIVAKAMLQSAGSKFTTFQEALLYLYKNEGLKSLWKGVLPQLTKGVIVQGLLFAFRGELTKSLKRLIFLYSSFFLKHNGQRKLAST | |
Gene Information
Gene Ontology (GO Annotations)
| GO ID | Source | Type | Description |
|---|---|---|---|
| GO:0005779 | IDA:SGD | C | integral component of peroxisomal membrane |
| GO:0000295 | IDA:SGD | F | adenine nucleotide transmembrane transporter activity |
| GO:0015867 | IDA:SGD | P | ATP transport |
| GO:0006635 | IMP:SGD | P | fatty acid beta-oxidation |
| GO:0007031 | IMP:SGD | P | peroxisome organization |
| GO:0015992 | IEA:UniProtKB-KW | P | proton transport |
REACTOME Pathway Links
Domain Information
UniProt Annotations
Entry Information
Comments
| Comment Type | Description |
|---|---|
| Function | Adenine nucleotide transporter involved in the uniport of ATP and adenine nucleotide hetero-exchange transport between the cytosol and the peroxisomal lumen. This transport is accompanied by a proton transport from the peroxisomal lumen to the cytosol. Transport of ATP into the peroxisome is required for beta-oxidation of medium-chain fatty acids. Required for growth on medium-chain fatty acids, pH gradient formation in peroxisomes and for normal peroxisome proliferation. {ECO:0000269|PubMed:11390660, ECO:0000269|PubMed:11566870, ECO:0000269|PubMed:15219179, ECO:0000269|PubMed:15316083}. |
| Induction | Induced by oleic acid, through its ORE-like (oleate responsive element) promoter element and the PIP2-OAF1 transcription factors. {ECO:0000269|PubMed:12071844}. |
| Miscellaneous | Present with 2250 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}. |
| Similarity | Belongs to the mitochondrial carrier (TC 2.A.29) family. {ECO:0000305}. |
| Similarity | Contains 3 Solcar repeats. {ECO:0000255|PROSITE- ProRule:PRU00282}. |
| Subcellular Location | Peroxisome membrane {ECO:0000269|PubMed:11390660, ECO:0000269|PubMed:11566870, ECO:0000269|PubMed:14562095}; Multi-pass membrane protein {ECO:0000269|PubMed:11390660, ECO:0000269|PubMed:11566870, ECO:0000269|PubMed:14562095}. |
Identical and Related Proteins
Unique RefSeq proteins for LMP007363 (as displayed in Record Overview)
Identical Sequences to LMP007363 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:6325385 | GenBank | EIW07233.1 | 328 | Ant1p [Saccharomyces cerevisiae CEN.PK113-7D] |
| GI:6325385 | GenBank | EWG82907.1 | 328 | Ant1p [Saccharomyces cerevisiae R008] |
| GI:6325385 | GenBank | EWG88238.1 | 328 | Ant1p [Saccharomyces cerevisiae P301] |
| GI:6325385 | GenBank | EWG92768.1 | 328 | Ant1p [Saccharomyces cerevisiae R103] |
| GI:6325385 | GenBank | EWH15588.1 | 328 | Ant1p [Saccharomyces cerevisiae P283] |
| GI:6325385 | gnl | McCuskerlabDuke | 328 | Ant1p [Saccharomyces cerevisiae YJM993] |
Related Sequences to LMP007363 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:6325385 | DBBJ | GAA27086.1 | 328 | K7_Ant1p [Saccharomyces cerevisiae Kyokai no. 7] |
| GI:6325385 | GenBank | EDN61249.1 | 328 | adenine nucleotide transporter [Saccharomyces cerevisiae YJM789] |
| GI:6325385 | GenBank | EEU08335.1 | 328 | Ant1p [Saccharomyces cerevisiae JAY291] |
| GI:6325385 | GenBank | EGA56404.1 | 328 | Ant1p [Saccharomyces cerevisiae FostersB] |
| GI:6325385 | GenBank | EGA60134.1 | 464 | Ant1p [Saccharomyces cerevisiae FostersO] |
| GI:6325385 | GenBank | EGA76480.1 | 360 | Ant1p [Saccharomyces cerevisiae Vin13] |