Gene/Proteome Database (LMPD)

LMPD ID
LMP007374
Gene ID
850698
Species
Saccharomyces cerevisiae S288c (Yeast (S288c))
Gene Name
Lot6p
Gene Symbol
LOT6
Synonyms
-
Alternate Names
Lot6p
Chromosome
XII
EC Number
1.5.1.39

Proteins

Lot6p
Refseq ID NP_013111
Protein GI 6323039
UniProt ID Q07923
mRNA ID NM_001181898
Length 191
RefSeq Status PROVISIONAL
MKVGIIMGSVRAKRVCPEIAAYVKRTIENSEELIDQKLKIQVVDLQQIALPLYEDDDELIPAQIKSVDEYADSKTRSWSRIVNALDIIVFVTPQYNWGYPAALKNAIDRLYHEWHGKPALVVSYGGHGGSKCNDQLQEVLHGLKMNVIGGVAVKIPVGTIPLPEDIVPQLSVHNEEILQLLASCIETTRNK

Gene Information

Entrez Gene ID
850698
Gene Name
Lot6p
Gene Symbol
LOT6
Species
Saccharomyces cerevisiae S288c

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005829 IDA:SGD C cytosol
GO:0005634 IDA:SGD C nucleus
GO:0052874 IEA:UniProtKB-EC F FMN reductase (NADH) activity
GO:0052873 IEA:UniProtKB-EC F FMN reductase (NADPH) activity
GO:0003955 IDA:SGD F NAD(P)H dehydrogenase (quinone) activity
GO:0008134 IDA:SGD F transcription factor binding
GO:0006915 IMP:SGD P apoptotic process
GO:0034599 IMP:SGD P cellular response to oxidative stress
GO:0042994 IDA:SGD P cytoplasmic sequestering of transcription factor

Domain Information

InterPro Annotations

Accession Description
IPR029039 Flavoprotein-like
IPR005025 NADPH-dependent FMN reductase-like

UniProt Annotations

Entry Information

Gene Name
Lot6p
Protein Entry
LOT6_YEAST
UniProt ID
Q07923
Species
Yeast (S288c)

Comments

Comment Type Description
Catalytic Activity FMNH(2) + NAD(P)(+) = FMN + NAD(P)H.
Function Has several reductase activities that are NAD(P)H- dependent and involve FMN as a cofactor, ferricyanide being the best substrate for reduction. May be involved in ferric iron assimilation. {ECO:0000269|PubMed:15184374}.
Induction Induced by low temperature and by cycloheximide. {ECO:0000269|PubMed:11327734}.
Miscellaneous Present with 1270 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:14562095}. Nucleus {ECO:0000269|PubMed:14562095}.
Subunit Homodimer. {ECO:0000269|PubMed:15184374}.

Identical and Related Proteins

Unique RefSeq proteins for LMP007374 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
6323039 RefSeq NP_013111 191 Lot6p

Identical Sequences to LMP007374 proteins

Reference Database Accession Length Protein Name
GI:6323039 GenBank EIW09086.1 191 Lot6p [Saccharomyces cerevisiae CEN.PK113-7D]
GI:6323039 GenBank EWG84290.1 191 Lot6p [Saccharomyces cerevisiae R008]
GI:6323039 GenBank EWG89810.1 191 Lot6p [Saccharomyces cerevisiae P301]
GI:6323039 GenBank EWG94634.1 191 Lot6p [Saccharomyces cerevisiae R103]
GI:6323039 GenBank EWH17187.1 191 Lot6p [Saccharomyces cerevisiae P283]
GI:6323039 gnl McCuskerlabDuke 191 Lot6p [Saccharomyces cerevisiae YJM993]

Related Sequences to LMP007374 proteins

Reference Database Accession Length Protein Name
GI:6323039 DBBJ GAA24898.1 191 K7_Lot6p [Saccharomyces cerevisiae Kyokai no. 7]
GI:6323039 DBBJ GAD96741.1 208 NADPH-dependent FMN reductase Lot6, putative [Byssochlamys spectabilis No. 5]
GI:6323039 EMBL CDH11006.1 192 related to NAD(P)H-dependent FMN reductase LOT6 [Zygosaccharomyces bailii ISA1307]
GI:6323039 GenBank EGA73886.1 107 Lot6p [Saccharomyces cerevisiae AWRI796]
GI:6323039 GenBank EHN01301.1 186 Lot6p [Saccharomyces cerevisiae x Saccharomyces kudriavzevii VIN7]
GI:6323039 GenBank EJT44042.1 192 LOT6-like protein [Saccharomyces kudriavzevii IFO 1802]