Gene/Proteome Database (LMPD)

LMPD ID
LMP007388
Gene ID
851224
Species
Saccharomyces cerevisiae S288c (Yeast (S288c))
Gene Name
Spo7p
Gene Symbol
SPO7
Synonyms
-
Alternate Names
Spo7p
Chromosome
I

Proteins

Spo7p
Refseq ID NP_009393
Protein GI 6319310
UniProt ID P18410
mRNA ID NM_001178154
Length 259
RefSeq Status PROVISIONAL
MEPESIGDVGNHAQDDSASIVSGPRRRSTSKTSSAKNIRNSSNISPASMIFRNLLILEDDLRRQAHEQKILKWQFTLFLASMAGVGAFTFYELYFTSDYVKGLHRVILQFTLSFISITVVLFHISGQYRRTIVIPRRFFTSTNKGIRQFNVKLVKVQSTWDEKYTDSVRFVSRTIAYCNIYCLKKFLWLKDDNAIVKFWKSVTIQSQPRIGAVDVKLVLNPRAFSAEIREGWEIYRDEFWAREGARRRKQAHELRPKSE

Gene Information

Entrez Gene ID
851224
Gene Name
Spo7p
Gene Symbol
SPO7
Species
Saccharomyces cerevisiae S288c

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0071595 IPI:SGD C Nem1-Spo7 phosphatase complex
GO:0005783 IEA:UniProtKB-KW C endoplasmic reticulum
GO:0016021 IDA:SGD C integral component of membrane
GO:0005634 IEA:UniProtKB-KW C nucleus
GO:0016311 IDA:GOC P dephosphorylation
GO:0006629 IEA:UniProtKB-KW P lipid metabolic process
GO:0071072 IGI:SGD P negative regulation of phospholipid biosynthetic process
GO:0006998 IMP:SGD P nuclear envelope organization
GO:0030435 IEA:UniProtKB-KW P sporulation resulting in formation of a cellular spore

Domain Information

InterPro Annotations

Accession Description
IPR005605 Sporulation/nuclear morphology, Spo7

UniProt Annotations

Entry Information

Gene Name
Spo7p
Protein Entry
SPO7_YEAST
UniProt ID
P18410
Species
Yeast (S288c)

Comments

Comment Type Description
Function Required for sporulation. Essential for the formation of a spherical nucleus and meiotic division. Probable regulatory component of the NEM1-SPO7 complex which acts as a phosphatase and dephosphorylates PAH1/SMP2. {ECO:0000269|PubMed:15889145, ECO:0000269|PubMed:9822591}.
Interaction P38757:NEM1; NbExp=4; IntAct=EBI-17857, EBI-24435;
Miscellaneous Present with 861 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000269|PubMed:9822591}; Multi-pass membrane protein {ECO:0000269|PubMed:9822591}. Nucleus membrane {ECO:0000269|PubMed:9822591}; Multi-pass membrane protein {ECO:0000269|PubMed:9822591}.
Subunit Component of the NEM1-SPO7 complex. {ECO:0000269|PubMed:9822591}.

Identical and Related Proteins

Unique RefSeq proteins for LMP007388 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
6319310 RefSeq NP_009393 259 Spo7p

Identical Sequences to LMP007388 proteins

Reference Database Accession Length Protein Name
GI:6319310 DBBJ GAA21416.1 259 K7_Spo7p [Saccharomyces cerevisiae Kyokai no. 7]
GI:6319310 GenBank AAA35073.1 259 SPO7 protein [Saccharomyces cerevisiae]
GI:6319310 GenBank AAC04949.1 259 Spo7p [Saccharomyces cerevisiae]
GI:6319310 GenBank AAS56911.1 259 YAL009W [Saccharomyces cerevisiae]
GI:6319310 SwissProt P18410.1 259 RecName: Full=Sporulation-specific protein SPO7 [Saccharomyces cerevisiae S288c]
GI:6319310 Third Party Genbank DAA06979.1 259 TPA: Spo7p [Saccharomyces cerevisiae S288c]

Related Sequences to LMP007388 proteins

Reference Database Accession Length Protein Name
GI:6319310 GenBank EDN59755.1 259 conserved protein [Saccharomyces cerevisiae YJM789]
GI:6319310 GenBank EEU07286.1 259 Spo7p [Saccharomyces cerevisiae JAY291]
GI:6319310 GenBank EIW12356.1 259 Spo7p [Saccharomyces cerevisiae CEN.PK113-7D]
GI:6319310 GenBank EWG87914.1 259 Spo7p [Saccharomyces cerevisiae R008]
GI:6319310 GenBank EWG92678.1 259 Spo7p [Saccharomyces cerevisiae P301]
GI:6319310 GenBank EWG97723.1 259 Spo7p [Saccharomyces cerevisiae R103]