Gene/Proteome Database (LMPD)
Proteins
C-22 sterol desaturase | |
---|---|
Refseq ID | NP_013728 |
Protein GI | 6323657 |
UniProt ID | P54781 |
mRNA ID | NM_001182511 |
Length | 538 |
MSSVAENIIQHATHNSTLHQLAKDQPSVGVTTAFSILDTLKSMSYLKIFATLICILLVWDQVAYQIKKGSIAGPKFKFWPIIGPFLESLDPKFEEYKAKWASGPLSCVSIFHKFVVIASTRDLARKILQSSKFVKPCVVDVAVKILRPCNWVFLDGKAHTDYRKSLNGLFTKQALAQYLPSLEQIMDKYMDKFVRLSKENNYEPQVFFHEMREILCALSLNSFCGNYITEDQVRKIADDYYLVTAALELVNFPIIIPYTKTWYGKKTADMAMKIFENCAQMAKDHIAAGGKPVCVMDAWCKLMHDAKNSNDDDSRIYHREFTNKEISEAVFTFLFASQDASSSLACWLFQIVADRPDVLAKIREEQLAVRNNDMSTELNLDLIEKMKYTNMVIKETLRYRPPVLMVPYVVKKNFPVSPNYTAPKGAMLIPTLYPALHDPEVYENPDEFIPERWVEGSKASEAKKNWLVFGCGPHVCLGQTYVMITFAALLGKFALYTDFHHTVTPLSEKIKVFATIFPKDDLLLTFKKRDPITGEVFE |
Gene Information
Entrez Gene ID
Gene Name
C-22 sterol desaturase
Gene Symbol
Species
Saccharomyces cerevisiae S288c
Gene Ontology (GO Annotations)
GO ID | Source | Type | Description |
---|---|---|---|
GO:0000249 | IDA:SGD | F | C-22 sterol desaturase activity |
GO:0020037 | IEA:InterPro | F | heme binding |
GO:0005506 | IEA:InterPro | F | iron ion binding |
GO:0004497 | IEA:InterPro | F | monooxygenase activity |
GO:0006696 | IDA:SGD | P | ergosterol biosynthetic process |
KEGG Pathway Links
KEGG Pathway ID | Description |
---|---|
M00102 | Ergocalciferol biosynthesis |
sce_M00102 | Ergocalciferol biosynthesis |
sce01100 | Metabolic pathways |
ko00100 | Steroid biosynthesis |
sce00100 | Steroid biosynthesis |
BIOCYC Pathway Links
BIOCYC Pathway ID | Description |
---|---|
PWY-6075 | ergosterol biosynthesis |
PWY-6075 | ergosterol biosynthesis I |
ERGOSTEROL-SYN-PWY | superpathway of ergosterol biosynthesis |
ERGOSTEROL-SYN-PWY | superpathway of ergosterol biosynthesis I |
REACTOME Pathway Links
Domain Information
UniProt Annotations
Entry Information
Comments
Comment Type | Description |
---|---|
Cofactor | Name=heme; Xref=ChEBI:CHEBI:30413; Evidence= ; |
Cofactor | Name=heme; Xref=ChEBI:CHEBI:30413; Evidence={ECO:0000250}; |
Function | Required to form the C-22(23) double bond in the sterol side chain. |
Miscellaneous | Present with 24700 molecules/cell in log phase SD medium |
Miscellaneous | Present with 24700 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}. |
Pathway | Steroid metabolism; ergosterol biosynthesis; ergosterol from zymosterol: step 4/5. |
Similarity | Belongs to the cytochrome P450 family |
Similarity | Belongs to the cytochrome P450 family. {ECO:0000305}. |
Subunit | Interacts with ERG28 |
Subunit | Interacts with ERG28. {ECO:0000269|PubMed:15995173}. |
Identical and Related Proteins
Unique RefSeq proteins for LMP007400 (as displayed in Record Overview)
Protein GI | Database | Accession | Length | Protein Name |
---|---|---|---|---|
6323657 | RefSeq | NP_013728 | 538 | C-22 sterol desaturase |
Identical Sequences to LMP007400 proteins
Reference | Database | Accession | Length | Protein Name |
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Related Sequences to LMP007400 proteins
Reference | Database | Accession | Length | Protein Name |
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