LIPID MAPS

LMPD ID

LMP007416

Gene ID

Species

Saccharomyces cerevisiae S288c (Yeast (S288c))

Gene Name

Pdr16p

Gene Symbol

PDR16

Synonyms

SFH3

Chromosome

XIV

Pdr16p
Refseq ID	NP_014168
Protein GI	6324098
UniProt ID	P53860
mRNA ID	NM_001183069
Length	351
MFKRFSKKKEAPEDPKNLINIDKPIKELPASIAIPKEKPLTGEQQKMYDEVLKHFSNPDLKVYTSEKNKSEDDLKPLEEEEKAWLTRECFLRYLRATKWVLKDCIDRITMTLAWRREFGISHLGEEHGDKITADLVAVENESGKQVILGYENDARPILYLKPGRQNTKTSHRQVQHLVFMLERVIDFMPAGQDSLALLIDFKDYPDVPKVPGNSKIPPIGVGKEVLHILQTHYPERLGKALLTNIPWLAWTFLKLIHPFIDPLTREKLVFDEPFVKYVPKNELDSLYGGDLKFKYNHDVYWPALVETAREKRDHYFKRFQSFGGIVGLSEVDLRGTHEKLLYPVKSESSTV

Entrez Gene ID

Gene Name

Pdr16p

Gene Symbol

PDR16

Species

Saccharomyces cerevisiae S288c

GO ID	Source	Type	Description
GO:0071944	IDA:SGD	C	cell periphery
GO:0005783	IEA:UniProtKB-KW	C	endoplasmic reticulum
GO:0005811	IDA:SGD	C	lipid particle
GO:0016020	IEA:UniProtKB-KW	C	membrane
GO:0042802	IPI:IntAct	F	identical protein binding
GO:0008526	IDA:SGD	F	phosphatidylinositol transporter activity
GO:0043942	IMP:SGD	P	negative regulation of sexual sporulation resulting in formation of a cellular spore
GO:0008654	IGI:SGD	P	phospholipid biosynthetic process
GO:0015914	IDA:SGD	P	phospholipid transport
GO:0042493	IGI:SGD	P	response to drug
GO:0016126	IGI:SGD	P	sterol biosynthetic process

Accession	Description
IPR001251	CRAL-TRIO domain
IPR011074	CRAL/TRIO, N-terminal domain

Gene Name

Pdr16p

Protein Entry

PDR16_YEAST

UniProt ID

Species

Yeast (S288c)

Comment Type	Description
Function	Has phosphatidylinositol transfer activity. Involved in the regulation of the phospholipid composition of plasma- and endomembranes. Altering plasma membrane composition may provide a possible mechanism for multidrug resistance. Involved in the regulation of sterol biosynthesis. Contributes to efficient phospholipase D1 activation in the regulation of phospholipid turnover. {ECO:0000269\|PubMed:10848624, ECO:0000269\|PubMed:9890948}.
Interaction	Self; NbExp=2; IntAct=EBI-29195, EBI-29195;
Miscellaneous	Present with 15361 molecules/cell in log phase SD medium
Miscellaneous	Present with 15361 molecules/cell in log phase SD medium. {ECO:0000269\|PubMed:14562106}.
Similarity	Contains 1 CRAL-TRIO domain. {ECO:0000255\|PROSITE- ProRule:PRU00056}.
Subcellular Location	Lipid droplet. Microsome membrane; Peripheral membrane protein. Endoplasmic reticulum membrane {ECO:0000305}; Peripheral membrane protein .
Subcellular Location	Lipid droplet. Microsome membrane; Peripheral membrane protein. Endoplasmic reticulum membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}.