LIPID MAPS

LMPD ID

LMP007419

Gene ID

Species

Saccharomyces cerevisiae S288c (Yeast (S288c))

Gene Name

Bst1p

Gene Symbol

BST1

Synonyms

PER17

Chromosome

VI

EC Number

3.1.-.-

Bst1p
Refseq ID	NP_116628
Protein GI	14318494
UniProt ID	P43571
mRNA ID	NM_001179941
Length	1029
MGIRRLVSVITRPIINKVNSSGQYSRVLATREDQDKASPKYMNNDKIAKKPYTYRLFSILGILSICSLLLISLLKPFNGADAPQCESIYMFPSYARIDGFDERYTPLAHKYHLYLYREQSVDREPLNGDELQLDGIPVLFIPGNAGSFRQCRSIASACSNIYFDSNTRATLRNENVRNLDFFTADFNEDFTAFHGETMLDQAEYLNDAIKYILSLYERTPDYPHPKPQSVIIVGHSMGGIVSRVMLTLKNHVPGSISTILTLSSPHAASPVTFDGDILKLYKNTNEYWRKQLSQNDSFFSKNISLVSITGGILDTTLPADYASVEDLVSLENGFTSFTTTIPDVWTPIDHLAIVWCKQLREVLARLLLESIDASKPEKVKPLNQRLQIARKLLLSGFEDYSWMNSKLNYPQENLQEFSDNFFSDYATLEMNDVLDFEMFNLEKWHNNYTKINIPSNISSTEHLHFTLLTSLDMPMIYFCTESRVNLSCITAVDSILTVPRSSKDTQFAADSSFGEAKNPFKAVSVGKNILQKYDYLMISKPTYGEFSEQEGMEDNQGFLLALLRNVSNVQIVNTTPSQILLFGEQLHLDGKDIEQVISFSNLWDSLLSYKLETKIEASNEGIASEETLFQPFIRQWVYEPFESKWHLNIINKSLDINMHNVAPFIPLNESEPRSLQLSFFIPPGMSLEAKMTINWSLTLKMLFIRYRLALASFPVAFIALVLSYQFYWYNKTSEFPSFDSTLGYILRKHGILMFFTLFLASPVVNNKLVQRILYLLDPVGLNYPFLLSERNMHANFYYLGIRDWFMSTIGILFGVMTVGLLALVSKIFGSLEILVIFLQRKLSKKNTEDKEAFDTIEHKAYGKGRLMASVLLLLLVFFHIPYQMAFVISLVIQIATCIRVALLKLSNNEQKLNLLNYNMTLLLLLLFVSAINIPIIIVFLHNVAIKWETSFRSHHNILAVAPIIFLVGNNSIFKMPNSVPLDTWDGKVTIILFVYLTVFSFIYGIRNLYWIHHLVNIICAWLLFFETIH

Entrez Gene ID

Gene Name

Bst1p

Gene Symbol

BST1

Species

Saccharomyces cerevisiae S288c

GO ID	Source	Type	Description
GO:0005783	IDA:SGD	C	endoplasmic reticulum
GO:0016021	ISS:SGD	C	integral component of membrane
GO:0050185	IGI:SGD	F	phosphatidylinositol deacylase activity
GO:0006888	IMP:SGD	P	ER to Golgi vesicle-mediated transport
GO:0030433	IMP:SGD	P	ER-associated ubiquitin-dependent protein catabolic process
GO:0006505	IGI:SGD	P	GPI anchor metabolic process
GO:0006886	IEA:InterPro	P	intracellular protein transport
GO:0006621	IMP:SGD	P	protein retention in ER lumen
GO:0016050	IMP:SGD	P	vesicle organization

KEGG Pathway ID	Description
ko00563	Glycosylphosphatidylinositol(GPI)-anchor biosynthesis
sce00563	Glycosylphosphatidylinositol(GPI)-anchor biosynthesis
sce01100	Metabolic pathways

Accession	Description
IPR029058	Alpha/Beta hydrolase fold
IPR012908	GPI inositol-deacylase PGAP1-like

Gene Name

Bst1p

Protein Entry

BST1_YEAST

UniProt ID

Species

Yeast (S288c)

Comment Type	Description
Function	Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins. Required for the transport of misfolded protein to the Golgi, although dipensable for the transport of many normal proteins. {ECO:0000269\|PubMed:11673477, ECO:0000269\|PubMed:14734546, ECO:0000269\|PubMed:16319176, ECO:0000269\|PubMed:8862519}.
Ptm	Glycosylated
Ptm	Glycosylated. {ECO:0000269\|PubMed:8862519}.
Similarity	Belongs to the GPI inositol-deacylase family
Similarity	Belongs to the GPI inositol-deacylase family. {ECO:0000305}.
Subcellular Location	Endoplasmic reticulum membrane ; Multi-pass membrane protein .
Subcellular Location	Endoplasmic reticulum membrane {ECO:0000269\|PubMed:14562095}; Multi-pass membrane protein {ECO:0000269\|PubMed:14562095}.