Gene/Proteome Database (LMPD)

LMPD ID
LMP007430
Gene ID
856464
Species
Saccharomyces cerevisiae S288c (Yeast (S288c))
Gene Name
hydroxyacyl-thioester dehydratase HTD2
Gene Symbol
HTD2
Synonyms
RMD12
Chromosome
VIII
EC Number
4.2.1.-

Proteins

hydroxyacyl-thioester dehydratase HTD2
Refseq ID NP_011934
Protein GI 6321858
UniProt ID P38790
mRNA ID NM_001179197
Length 280
MKSKTWIFRDVLSSHRTKAFDSLLCRRLPVSKATKHLQLGEHFLFFPPSFEKLDRDGYFNYQNPASLLGNPDLRYRRRIWGQGELVQYLPVTLDQEYTCHESIKYVKKIRDEHVVCIERTLLQERPENVSSPMDICLFERRVLMYTNSPANKTAVKMPVGEENYKILKNFTVTDMDIVAYGQMSLNPHRIHWDKEYSRYVEGYDDIIMQGPFSVQLLQKCIQPFLEQPIRQLRYRNLNYIYPNTTLSICQSLSSSSGMYTFQIRDLQKANLVYMKADVFC

Gene Information

Entrez Gene ID
856464
Gene Name
hydroxyacyl-thioester dehydratase HTD2
Gene Symbol
HTD2
Species
Saccharomyces cerevisiae S288c

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005739 IDA:SGD C mitochondrion
GO:0019171 IDA:SGD F 3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity
GO:0016491 IEA:UniProtKB-KW F oxidoreductase activity
GO:0006633 IGI:SGD P fatty acid biosynthetic process

BIOCYC Pathway Links

BIOCYC Pathway ID Description
PWY-7388 octanoyl-ACP biosynthesis (mitochondria)
PWY-7388 octanoyl-ACP biosynthesis (mitochondria, yeast)
PWY-5994 palmitate biosynthesis
PWY-5994 palmitate biosynthesis I (animals and fungi)

Domain Information

InterPro Annotations

Accession Description
IPR026223 HTD2
IPR029069 HotDog domain

UniProt Annotations

Entry Information

Gene Name
hydroxyacyl-thioester dehydratase HTD2
Protein Entry
HTD2_YEAST
UniProt ID
P38790
Species
Yeast (S288c)

Comments

Comment Type Description
Function Mitochondrial 3-hydroxyacyl-thioester dehydratase involved in fatty acid biosynthesis. Required for respiratory growth and for normal mitochondrial morphology
Function Mitochondrial 3-hydroxyacyl-thioester dehydratase involved in fatty acid biosynthesis. Required for respiratory growth and for normal mitochondrial morphology. {ECO:0000269|PubMed:15387819}.
Interaction P33203:PRP40; NbExp=1; IntAct=EBI-24577, EBI-701;
Miscellaneous Present with 799 molecules/cell in log phase SD medium
Miscellaneous Present with 799 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
Similarity Belongs to the HTD2 family
Similarity Belongs to the HTD2 family. {ECO:0000305}.
Subcellular Location Mitochondrion {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:15387819, ECO:0000269|PubMed:16823961}.

Identical and Related Proteins

Unique RefSeq proteins for LMP007430 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
6321858 RefSeq NP_011934 280 hydroxyacyl-thioester dehydratase HTD2

Identical Sequences to LMP007430 proteins

Reference Database Accession Length Protein Name

Related Sequences to LMP007430 proteins

Reference Database Accession Length Protein Name