Gene/Proteome Database (LMPD)

LMPD ID
LMP007437
Gene ID
852476
Species
Saccharomyces cerevisiae S288c (Yeast (S288c))
Gene Name
Eht1p
Gene Symbol
EHT1
Synonyms
-
Alternate Names
Eht1p
Chromosome
II
EC Number
2.3.1.84

Proteins

Eht1p
Refseq ID NP_009736
Protein GI 398365307
UniProt ID P38295
mRNA ID NM_001178525
Length 451
RefSeq Status PROVISIONAL
MSEVSKWPAINPFHWGYNGTVSHIVGENGSIKLHLKDNKEQVDFDEFANKYVPTLKNGAQFKLSPYLFTGILQTLYLGAADFSKKFPVFYGREIVKFSDGGVCTADWLIDSWKKDYEFDQSTTSFDKKKFDKDEKATHPEGWPRLQPRTRYLKDNELEELREVDLPLVVILHGLAGGSHEPIIRSLAENLSRSGRFQVVVLNTRGCARSKITTRNLFTAYHTMDIREFLQREKQRHPDRKLYAVGCSFGATMLANYLGEEGDKSPLSAAATLCNPWDLLLSAIRMSQDWWSRTLFSKNIAQFLTRTVQVNMGELGVPNGSLPDHPPTVKNPSFYMFTPENLIKAKSFKSTREFDEVYTAPALGFPNAMEYYKAASSINRVDTIRVPTLVINSRDDPVVGPDQPYSIVEKNPRILYCRTDLGGHLAYLDKDNNSWATKAIAEFFTKFDELVV

Gene Information

Entrez Gene ID
852476
Gene Name
Eht1p
Gene Symbol
EHT1
Species
Saccharomyces cerevisiae S288c

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005811 IDA:SGD C lipid particle
GO:0004026 IEA:UniProtKB-EC F alcohol O-acetyltransferase activity
GO:0034319 IDA:SGD F alcohol O-butanoyltransferase activity
GO:0034338 IDA:SGD F short-chain carboxylesterase activity
GO:0044255 IMP:SGD P cellular lipid metabolic process
GO:0051792 IDA:SGD P medium-chain fatty acid biosynthetic process
GO:0051793 IMP:SGD P medium-chain fatty acid catabolic process

Domain Information

InterPro Annotations

Accession Description
IPR012020 AB-hydrolase YheT, putative
IPR029058 Alpha/Beta hydrolase fold
IPR000073 Alpha/beta hydrolase fold-1
IPR000952 Uncharacterised protein family UPF0017, hydrolase-like, conserved site

UniProt Annotations

Entry Information

Gene Name
Eht1p
Protein Entry
MCFS2_YEAST
UniProt ID
P38295
Species
Yeast (S288c)

Comments

Comment Type Description
Catalytic Activity Acetyl-CoA + an alcohol = CoA + an acetyl ester.
Function Displays enzymatic activity both for medium-chain fatty acid (MCFA) ethyl ester synthesis and hydrolysis (esterase activity). MCFA are toxic for yeast and this enzyme could thus be involved in their detoxification by esterification. {ECO:0000269|PubMed:16361250}.
Interaction Self; NbExp=1; IntAct=EBI-20890, EBI-20890; Q12168:ACF2; NbExp=1; IntAct=EBI-20890, EBI-32973; P25376:AGP1; NbExp=1; IntAct=EBI-20890, EBI-2357; P54783:ALO1; NbExp=1; IntAct=EBI-20890, EBI-2519; P53090:ARO8; NbExp=1; IntAct=EBI-20890, EBI-2042933; P40471:AYR1; NbExp=1; IntAct=EBI-20890, EBI-25213; P32582:CYS4; NbExp=1; IntAct=EBI-20890, EBI-4167; P47133:EMC2; NbExp=1; IntAct=EBI-20890, EBI-25568; P10614:ERG11; NbExp=1; IntAct=EBI-20890, EBI-5127; P38604:ERG7; NbExp=1; IntAct=EBI-20890, EBI-6572; P38225:FAT1; NbExp=1; IntAct=EBI-20890, EBI-6819; P39958:GDI1; NbExp=1; IntAct=EBI-20890, EBI-7517; P00817:IPP1; NbExp=1; IntAct=EBI-20890, EBI-9338; P35844:KES1; NbExp=1; IntAct=EBI-20890, EBI-9648; P25297:PHO84; NbExp=1; IntAct=EBI-20890, EBI-13320; P40975:PMP2; NbExp=1; IntAct=EBI-20890, EBI-2043041; P87284:PMP3; NbExp=1; IntAct=EBI-20890, EBI-13555; P26570:PPZ1; NbExp=1; IntAct=EBI-20890, EBI-13807; P35196:RER2; NbExp=1; IntAct=EBI-20890, EBI-14943; P39940:RSP5; NbExp=1; IntAct=EBI-20890, EBI-16219; Q04947:RTN1; NbExp=1; IntAct=EBI-20890, EBI-38020; P32368:SAC1; NbExp=1; IntAct=EBI-20890, EBI-16210; P14359:SNA3; NbExp=1; IntAct=EBI-20890, EBI-26122; P39986:SPF1; NbExp=1; IntAct=EBI-20890, EBI-3128; P34163:TGL1; NbExp=1; IntAct=EBI-20890, EBI-19177; P35180:TOM20; NbExp=1; IntAct=EBI-20890, EBI-12522; P25037:UBP1; NbExp=1; IntAct=EBI-20890, EBI-19819; P32610:VMA8; NbExp=1; IntAct=EBI-20890, EBI-20264; P0C268:YBL039W-B; NbExp=1; IntAct=EBI-20890, EBI-2044092; Q07804:YEH1; NbExp=1; IntAct=EBI-20890, EBI-36254; P35723:YET1; NbExp=1; IntAct=EBI-20890, EBI-26730; P38756:YHR003C; NbExp=1; IntAct=EBI-20890, EBI-24431; P28321:YJU3; NbExp=1; IntAct=EBI-20890, EBI-26790;
Miscellaneous Present with 2550 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
Similarity Belongs to the AB hydrolase superfamily. AB hydrolase 4 family. {ECO:0000305}.

Identical and Related Proteins

Unique RefSeq proteins for LMP007437 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
398365307 RefSeq NP_009736 451 Eht1p

Identical Sequences to LMP007437 proteins

Reference Database Accession Length Protein Name
GI:398365307 EMBL CAA85138.1 451 unnamed protein product [Saccharomyces cerevisiae]
GI:398365307 GenBank EIW12112.1 451 Eht1p [Saccharomyces cerevisiae CEN.PK113-7D]
GI:398365307 SwissProt P38295.1 451 RecName: Full=Medium-chain fatty acid ethyl ester synthase/esterase 2; AltName: Full=Alcohol O-acetyltransferase; AltName: Full=Ethanol hexanoyl transferase 1 [Saccharomyces cerevisiae S288c]
GI:398365307 Third Party Genbank DAA07292.1 451 TPA: Eht1p [Saccharomyces cerevisiae S288c]

Related Sequences to LMP007437 proteins

Reference Database Accession Length Protein Name
GI:398365307 DBBJ BAA76441.1 451 alcohol acyl transferase [Saccharomyces cerevisiae]
GI:398365307 DBBJ GAA21722.1 451 K7_Eht1p [Saccharomyces cerevisiae Kyokai no. 7]
GI:398365307 EMBL CBK39252.1 451 Eht1p [Saccharomyces cerevisiae EC1118]
GI:398365307 GenBank EDV11936.1 451 acyl-coenzymeA:ethanol O-acyltransferase [Saccharomyces cerevisiae RM11-1a]
GI:398365307 GenBank EHN08378.1 451 Eht1p [Saccharomyces cerevisiae x Saccharomyces kudriavzevii VIN7]
GI:398365307 gnl McCuskerlabDuke 451 Eht1p [Saccharomyces cerevisiae YJM993]