Gene/Proteome Database (LMPD)

LMPD ID
LMP007443
Gene ID
855103
Species
Saccharomyces cerevisiae S288c (Yeast (S288c))
Gene Name
phosphatidylinositol/phosphatidylcholine transfer protein SEC14
Gene Symbol
SEC14
Synonyms
PIT1
Chromosome
XIII

Proteins

phosphatidylinositol/phosphatidylcholine transfer protein SEC14
Refseq ID NP_013796
Protein GI 6323725
UniProt ID P24280
mRNA ID NM_001182578
Length 304
MVTQQEKEFLESYPQNCPPDALPGTPGNLDSAQEKALAELRKLLEDAGFIERLDDSTLLRFLRARKFDVQLAKEMFENCEKWRKDYGTDTILQDFHYDEKPLIAKFYPQYYHKTDKDGRPVYFEELGAVNLHEMNKVTSEERMLKNLVWEYESVVQYRLPACSRAAGHLVETSCTIMDLKGISISSAYSVMSYVREASYISQNYYPERMGKFYIINAPFGFSTAFRLFKPFLDPVTVSKIFILGSSYQKELLKQIPAENLPVKFGGKSEVDESKGGLYLSDIGPWRDPKYIGPEGEAPEAFSMK

Gene Information

Entrez Gene ID
855103
Gene Name
phosphatidylinositol/phosphatidylcholine transfer protein SEC14
Gene Symbol
SEC14
Species
Saccharomyces cerevisiae S288c

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005737 IDA:SGD C cytoplasm
GO:0005829 IDA:SGD C cytosol
GO:0005794 IDA:SGD C Golgi apparatus
GO:0000139 IDA:SGD C Golgi membrane
GO:0008525 IDA:SGD F phosphatidylcholine transporter activity
GO:0008526 IDA:SGD F phosphatidylinositol transporter activity
GO:0030437 IMP:SGD P ascospore formation
GO:0043001 IMP:SGD P Golgi to plasma membrane protein transport
GO:0006896 IMP:SGD P Golgi to vacuole transport
GO:0048194 IDA:SGD P Golgi vesicle budding
GO:2001246 IDA:SGD P negative regulation of phosphatidylcholine biosynthetic process
GO:1901352 IMP:SGD P negative regulation of phosphatidylglycerol biosynthetic process
GO:0046488 IMP:SGD P phosphatidylinositol metabolic process
GO:0015914 IDA:SGD P phospholipid transport

Domain Information

InterPro Annotations

Accession Description
IPR001071 Cellular retinaldehyde binding/alpha-tocopherol transport
IPR001251 CRAL-TRIO domain
IPR011074 CRAL/TRIO, N-terminal domain

UniProt Annotations

Entry Information

Gene Name
phosphatidylinositol/phosphatidylcholine transfer protein SEC14
Protein Entry
SEC14_YEAST
UniProt ID
P24280
Species
Yeast (S288c)

Comments

Comment Type Description
Function Required for transport of secretory proteins from the Golgi complex. Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes in vitro. Essential for viability and secretion.
Interaction P38797:PTC7; NbExp=3; IntAct=EBI-16535, EBI-24588;
Miscellaneous Present with 84300 molecules/cell in log phase SD medium
Miscellaneous Present with 84300 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
Similarity Contains 1 CRAL-TRIO domain. {ECO:0000255|PROSITE- ProRule:PRU00056}.
Subcellular Location Golgi apparatus membrane; Peripheral membrane protein.

Identical and Related Proteins

Unique RefSeq proteins for LMP007443 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
6323725 RefSeq NP_013796 304 phosphatidylinositol/phosphatidylcholine transfer protein SEC14

Identical Sequences to LMP007443 proteins

Reference Database Accession Length Protein Name

Related Sequences to LMP007443 proteins

Reference Database Accession Length Protein Name