Gene/Proteome Database (LMPD)

LMPD ID
LMP007494
Gene ID
853395
Species
Saccharomyces cerevisiae S288c (Yeast (S288c))
Gene Name
glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) TDH1
Gene Symbol
TDH1
Synonyms
GLD3
Chromosome
X
EC Number
1.2.1.12;

Proteins

glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) TDH1
Refseq ID NP_012483
Protein GI 398364523
UniProt ID P00360
mRNA ID NM_001181485
Length 332
MIRIAINGFGRIGRLVLRLALQRKDIEVVAVNDPFISNDYAAYMVKYDSTHGRYKGTVSHDDKHIIIDGVKIATYQERDPANLPWGSLKIDVAVDSTGVFKELDTAQKHIDAGAKKVVITAPSSSAPMFVVGVNHTKYTPDKKIVSNASCTTNCLAPLAKVINDAFGIEEGLMTTVHSMTATQKTVDGPSHKDWRGGRTASGNIIPSSTGAAKAVGKVLPELQGKLTGMAFRVPTVDVSVVDLTVKLEKEATYDQIKKAVKAAAEGPMKGVLGYTEDAVVSSDFLGDTHASIFDASAGIQLSPKFVKLISWYDNEYGYSARVVDLIEYVAKA

Gene Information

Entrez Gene ID
853395
Gene Name
glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) TDH1
Gene Symbol
TDH1
Species
Saccharomyces cerevisiae S288c

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005737 IDA:SGD C cytoplasm
GO:0009277 IDA:SGD C fungal-type cell wall
GO:0005811 IDA:SGD C lipid particle
GO:0005739 IDA:SGD C mitochondrion
GO:0051287 IEA:InterPro F NAD binding
GO:0050661 IEA:InterPro F NADP binding
GO:0004365 IDA:SGD F glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GO:0006094 IEP:SGD P gluconeogenesis
GO:0006096 IEP:SGD P glycolytic process

KEGG Pathway Links

KEGG Pathway ID Description
ko01230 Biosynthesis of amino acids
sce01230 Biosynthesis of amino acids
sce01110 Biosynthesis of secondary metabolites
ko01200 Carbon metabolism
sce01200 Carbon metabolism
M00003 Gluconeogenesis, oxaloacetate => fructose-6P
sce_M00003 Gluconeogenesis, oxaloacetate => fructose-6P
M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
sce_M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
ko00010 Glycolysis / Gluconeogenesis
sce00010 Glycolysis / Gluconeogenesis
M00002 Glycolysis, core module involving three-carbon compounds
sce_M00002 Glycolysis, core module involving three-carbon compounds
sce01100 Metabolic pathways

BIOCYC Pathway Links

BIOCYC Pathway ID Description
GLUCONEO-YEAST-PWY gluconeogenesis
GLYCOLYSIS-YEAST-PWY glycolysis
ANAGLYCOLYSIS-PWY glycolysis III (glucokinase)

REACTOME Pathway Links

REACTOME Pathway ID Description
5618026 Disease
5618020 Gluconeogenesis
5618021 Glucose metabolism
5618025 Glycogen storage diseases
5618039 Glycolysis
5618023 Metabolism
5618022 Metabolism of carbohydrates
5618024 Myoclonic epilepsy of Lafora

Domain Information

InterPro Annotations

Accession Description
IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain
IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site
IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain
IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I
IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family
IPR016040 NAD(P)-binding domain

UniProt Annotations

Entry Information

Gene Name
glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) TDH1
Protein Entry
G3P1_YEAST
UniProt ID
P00360
Species
Yeast (S288c)

Comments

Comment Type Description
Catalytic Activity D-glyceraldehyde 3-phosphate + phosphate + NAD(+) = 3-phospho-D-glyceroyl phosphate + NADH
Catalytic Activity D-glyceraldehyde 3-phosphate + phosphate + NAD(+) = 3-phospho-D-glyceroyl phosphate + NADH. {ECO:0000255|PROSITE-ProRule:PRU10009}.
Miscellaneous Present with 120000 molecules/cell in log phase SD medium
Miscellaneous Present with 120000 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
Miscellaneous There are three genes for G3PDH in yeast.
Pathway Carbohydrate degradation; glycolysis; pyruvate from D- glyceraldehyde 3-phosphate: step 1/5.
Similarity Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
Similarity Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. {ECO:0000305}.
Subcellular Location Cytoplasm .
Subcellular Location Cytoplasm {ECO:0000269|PubMed:11502169}.
Subunit Homotetramer.

Identical and Related Proteins

Unique RefSeq proteins for LMP007494 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
398364523 RefSeq NP_012483 332 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) TDH1

Identical Sequences to LMP007494 proteins

Reference Database Accession Length Protein Name

Related Sequences to LMP007494 proteins

Reference Database Accession Length Protein Name