LIPID MAPS

LMPD ID

LMP007515

Gene ID

Species

Saccharomyces cerevisiae S288c (Yeast (S288c))

Gene Name

Tgl5p

Gene Symbol

TGL5

Synonyms

STC2

Chromosome

XV

EC Number

3.1.1.3

Tgl5p
Refseq ID	NP_014724
Protein GI	6324655
UniProt ID	Q12043
mRNA ID	NM_001183500
Length	749
MSNTLPVTEFLLSKYYELSNTPATDSSSLFKWLYHKTLSRKQLLISDLSSQKKHAISYDQWNDIASRLDDLTGLSEWKTIDESSLYNYKLLQDLTIRMRHLRTTHDYHRLLYLIRTKWVRNLGNMNNVNLYRHSHTGTKQIIHDYLEESQAVLTALIHQSNMNDHYLLGILQQTRRNIGRTALVLSGGSTFGLFHIGVLAALFESDLMPKVISGSSAGAIVASIFCVHTTQEIPSLLTNVLNMEFNIFNDDNSKSPNENLLIKISRFCQNGTWFNNQPLINTMLSFLGNLTFREAYNKTGKILNITVSPASIYEQPKLLNNLTAPNVLIWSAVCASCSLPGVFPSTPLFEKDPHTGKIKEWGATNLHLSNMKFMDGSVDNDMPISRLSEMFNVDHIIACQVNIHVFPLLKFSNTCVGGEIEKEITARFRNQVTKIFKFFSDETIHFLDILKELEFHPYLMTKLKHLFLQQYSGNVTILPDLSMVGQFHEVLKNPSQLFLLHQTTLGARATWPKISMIQNNCGQEFALDKAITFLKEKIIISSSIKNPLQFYQPRFSEQIKSLSIMDADLPGVDLEESSSNSLSIIKSPNKTAAPGRFPLQPLPSPSSTFNKRKMDMLSPSPSPSTSPQRSKSSFTQQGTRQKANSLSFAIGASSLRLKKSPLKVPSRPQFKKRSSYYNQNMSAEMRKNRKKSGTISSYDVQTNSEDFPIPAIENGSFDNTLFNPSRFPMDAMSAATNDNFMNNSDIFQN

Entrez Gene ID

Gene Name

Tgl5p

Gene Symbol

TGL5

Species

Saccharomyces cerevisiae S288c

GO ID	Source	Type	Description
GO:0016021	IEA:UniProtKB-KW	C	integral component of membrane
GO:0005811	IDA:SGD	C	lipid particle
GO:0042171	IDA:SGD	F	lysophosphatidic acid acyltransferase activity
GO:0004806	IDA:SGD	F	triglyceride lipase activity
GO:0016042	IEA:UniProtKB-KW	P	lipid catabolic process
GO:0030435	IEA:UniProtKB-KW	P	sporulation resulting in formation of a cellular spore
GO:0006642	IDA:SGD	P	triglyceride mobilization

BIOCYC Pathway ID	Description
PWY-7417	phospholipid remodeling (phosphatidate)
PWY-7417	phospholipid remodeling (phosphatidate, yeast)
PWY-7411	superpathway phosphatidate biosynthesis (yeast)
PWY-7411	superpathway phosphatidate biosynthesis (yeast)
LIPAS-PWY	triacylglycerol degradation
LIPAS-PWY	triacylglycerol degradation

Accession	Description
IPR016035	Acyl transferase/acyl hydrolase/lysophospholipase
IPR002641	Patatin/Phospholipase A2-related
IPR021771	Triacylglycerol lipase

Gene Name

Tgl5p

Protein Entry

TGL5_YEAST

UniProt ID

Species

Yeast (S288c)

Comment Type	Description
Catalytic Activity	Triacylglycerol + H(2)O = diacylglycerol + a carboxylate.
Function	Releases specific fatty acids from neutral lipid triacylglycerols (TAG) thereby supplying fatty acids to a general acylation process. May have a specific role in sporulation
Function	Releases specific fatty acids from neutral lipid triacylglycerols (TAG) thereby supplying fatty acids to a general acylation process. May have a specific role in sporulation. {ECO:0000269\|PubMed:16135509}.
Interaction	Self; NbExp=1; IntAct=EBI-34845, EBI-34845; P32502:GCD7; NbExp=1; IntAct=EBI-34845, EBI-6260; P33892:GCN1; NbExp=1; IntAct=EBI-34845, EBI-7442; Q12525:MHT1; NbExp=1; IntAct=EBI-34845, EBI-37133; Q03529:SCS7; NbExp=1; IntAct=EBI-34845, EBI-16747; P31383:TPD3; NbExp=1; IntAct=EBI-34845, EBI-1936;
Miscellaneous	Present with 358 molecules/cell in log phase SD medium
Miscellaneous	Present with 358 molecules/cell in log phase SD medium. {ECO:0000269\|PubMed:14562106}.
Similarity	Contains 1 patatin domain
Similarity	Contains 1 patatin domain. {ECO:0000305}.
Subcellular Location	Lipid droplet. Membrane; Single-pass membrane protein. Note=Lipid particle.