Gene/Proteome Database (LMPD)

LMPD ID
LMP007522
Gene ID
852271
Species
Saccharomyces cerevisiae S288c (Yeast (S288c))
Gene Name
bifunctional glycerol-3-phosphate/glycerone-phosphate O-acyltransferase SCT1
Gene Symbol
SCT1
Synonyms
GAT2
Alternate Names
bifunctional glycerol-3-phosphate/glycerone-phosphate O-acyltransferase SCT1
Chromosome
II
EC Number
2.3.1.15

Proteins

bifunctional glycerol-3-phosphate/glycerone-phosphate O-acyltransferase SCT1
Refseq ID NP_009542
Protein GI 6319459
UniProt ID P32784
mRNA ID NM_001178251
Length 759
RefSeq Status PROVISIONAL
MPAPKLTEKFASSKSTQKTTNYSSIEAKSVKTSADQAYIYQEPSATKKILYSIATWLLYNIFHCFFREIRGRGSFKVPQQGPVIFVAAPHANQFVDPVILMGEVKKSVNRRVSFLIAESSLKQPPIGFLASFFMAIGVVRPQDNLKPAEGTIRVDPTDYKRVIGHDTHFLTDCMPKGLIGLPKSMGFGEIQSIESDTSLTLRKEFKMAKPEIKTALLTGTTYKYAAKVDQSCVYHRVFEHLAHNNCIGIFPEGGSHDRTNLLPLKAGVAIMALGCMDKHPDVNVKIVPCGMNYFHPHKFRSRAVVEFGDPIEIPKELVAKYHNPETNRDAVKELLDTISKGLQSVTVTCSDYETLMVVQTIRRLYMTQFSTKLPLPLIVEMNRRMVKGYEFYRNDPKIADLTKDIMAYNAALRHYNLPDHLVEEAKVNFAKNLGLVFFRSIGLCILFSLAMPGIIMFSPVFILAKRISQEKARTALSKSTVKIKANDVIATWKILIGMGFAPLLYIFWSVLITYYLRHKPWNKIYVFSGSYISCVIVTYSALIVGDIGMDGFKSLRPLVLSLTSPKGLQKLQKDRRNLAERIIEVVNNFGSELFPDFDSAALREEFDVIDEEEEDRKTSELNRRKMLRKQKIKRQEKDSSSPIISQRDNHDAYEHHNQDSDGVSLVNSDNSLSNIPLFSSTFHRKSESSLASTSVAPSSSSEFEVENEILEEKNGLASKIAQAVLNKRIGENTAREEEEEEEEEEEEEEEEEEGKEGDA

Gene Information

Entrez Gene ID
852271
Gene Name
bifunctional glycerol-3-phosphate/glycerone-phosphate O-acyltransferase SCT1
Gene Symbol
SCT1
Species
Saccharomyces cerevisiae S288c

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005783 IDA:SGD C endoplasmic reticulum
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0004366 IDA:SGD F glycerol-3-phosphate O-acyltransferase activity
GO:0016287 IDA:SGD F glycerone-phosphate O-acyltransferase activity
GO:0016024 IEA:UniProtKB-UniPathway P CDP-diacylglycerol biosynthetic process
GO:0008654 IMP:SGD P phospholipid biosynthetic process

KEGG Pathway Links

KEGG Pathway ID Description
sce00564 Glycerophospholipid metabolism

BIOCYC Pathway Links

BIOCYC Pathway ID Description
PWY-7411 superpathway phosphatidate biosynthesis (yeast)
TRIGLSYN-PWY triacylglycerol biosynthesis

Domain Information

InterPro Annotations

Accession Description
IPR002123 Phospholipid/glycerol acyltransferase

UniProt Annotations

Entry Information

Gene Name
bifunctional glycerol-3-phosphate/glycerone-phosphate O-acyltransferase SCT1
Protein Entry
GPT1_YEAST
UniProt ID
P32784
Species
Yeast (S288c)

Comments

Comment Type Description
Catalytic Activity Acyl-CoA + glycerone phosphate = CoA + acylglycerone phosphate.
Catalytic Activity Acyl-CoA + sn-glycerol 3-phosphate = CoA + 1- acyl-sn-glycerol 3-phosphate.
Domain The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate. {ECO:0000250}.
Function G-3-P/dihydroxyacetone phosphate dual substrate-specific sn-1 acyltransferase. {ECO:0000269|PubMed:11544256}.
Miscellaneous Present with 1050 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
Pathway Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 1/3.
Similarity Belongs to the GPAT/DAPAT family. {ECO:0000305}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000269|PubMed:14562095}; Multi-pass membrane protein {ECO:0000269|PubMed:14562095}.

Identical and Related Proteins

Unique RefSeq proteins for LMP007522 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
6319459 RefSeq NP_009542 759 bifunctional glycerol-3-phosphate/glycerone-phosphate O-acyltransferase SCT1

Identical Sequences to LMP007522 proteins

Reference Database Accession Length Protein Name
GI:6319459 EMBL CAA84831.1 759 SCT1 [Saccharomyces cerevisiae]
GI:6319459 SwissProt P32784.3 759 RecName: Full=Glycerol-3-phosphate O-acyltransferase 1; Short=G-3-P acyltransferase 1; AltName: Full=Dihydroxyacetone phosphate acyltransferase 1; Short=DHAP-AT 1; AltName: Full=Glycerol-3-phosphate / dihydroxyacetone phosphate acyltransferase 1; AltName: Full=Suppressor of choline-transport mutants 1 [Saccharomyces cerevisiae S288c]
GI:6319459 Third Party Genbank DAA07108.1 759 TPA: bifunctional glycerol-3-phosphate/glycerone-phosphate O-acyltransferase SCT1 [Saccharomyces cerevisiae S288c]

Related Sequences to LMP007522 proteins

Reference Database Accession Length Protein Name
GI:6319459 DBBJ BAA07409.1 759 SCT1 [Saccharomyces cerevisiae]
GI:6319459 DBBJ GAA21540.1 759 K7_Sct1p [Saccharomyces cerevisiae Kyokai no. 7]
GI:6319459 GenBank EDV12103.1 754 glycerol-3-phosphate O-acyltransferase 1 [Saccharomyces cerevisiae RM11-1a]
GI:6319459 GenBank EEU08111.1 754 Sct1p [Saccharomyces cerevisiae JAY291]
GI:6319459 GenBank EGA88076.1 754 Sct1p [Saccharomyces cerevisiae VL3]
GI:6319459 GenBank EIW12297.1 758 Sct1p [Saccharomyces cerevisiae CEN.PK113-7D]