Gene/Proteome Database (LMPD)
Proteins
| Pfa4p | |
|---|---|
| Refseq ID | NP_014640 |
| Protein GI | 6324571 |
| UniProt ID | Q12006 |
| mRNA ID | NM_001183257 |
| Length | 378 |
| RefSeq Status | PROVISIONAL |
| MPVKLRWPWLGIAIPTFLISFIGYGAHYFILSNFLSVPKQITFEFCLSMIWLSYYLAICTNPGRPLPNYKPPPDIWRNFCKKCQSYKPERSHHCKTCNQCVLMMDHHCPWTMNCVGFANYPHFLRFLFWIIVTTSVLFCIQAKRIYFIWQQRHLPGYFFKKSELIFLTISSPLNSFVLLTITILFLRCLFNQILNGRSQIESWDMDRLESLFNSGRLTQKLIDNTWRIYPESRSFQNKKDAEEHLTKKRPRFDELVNFPYDFDLYTNALLYLGPIHLWLWPYGVPTGDGNNFPKNGISKYEANSSLEDHILSLPWPPDGGKTNTVFNHGSSTIEMRNESGEQLIRTRLPQNGRHASREKWYNDWGESLDDFGVDVDME | |
Gene Information
Gene Ontology (GO Annotations)
| GO ID | Source | Type | Description |
|---|---|---|---|
| GO:0005783 | IDA:SGD | C | endoplasmic reticulum |
| GO:0016021 | IEA:UniProtKB-KW | C | integral component of membrane |
| GO:0016409 | IDA:UniProt | F | palmitoyltransferase activity |
| GO:0019706 | IEA:UniProtKB-EC | F | protein-cysteine S-palmitoyltransferase activity |
| GO:0008270 | IEA:InterPro | F | zinc ion binding |
| GO:0018345 | IDA:UniProt | P | protein palmitoylation |
Domain Information
InterPro Annotations
| Accession | Description |
|---|---|
| IPR001594 | Zinc finger, DHHC-type, palmitoyltransferase |
UniProt Annotations
Entry Information
Comments
| Comment Type | Description |
|---|---|
| Catalytic Activity | Palmitoyl-CoA + [protein]-L-cysteine = [protein]-S-palmitoyl-L-cysteine + CoA. |
| Domain | The DHHC domain is required for palmitoyltransferase activity. {ECO:0000250}. |
| Function | Can palmitoylate RAS2 in vitro. {ECO:0000269|PubMed:12379641}. |
| Ptm | Autopalmitoylated. |
| Similarity | Belongs to the DHHC palmitoyltransferase family. PFA4 subfamily. {ECO:0000305}. |
| Similarity | Contains 1 DHHC-type zinc finger. {ECO:0000255|PROSITE-ProRule:PRU00067}. |
| Subcellular Location | Endoplasmic reticulum membrane {ECO:0000269|PubMed:15973437}; Multi-pass membrane protein {ECO:0000269|PubMed:15973437}. |
Identical and Related Proteins
Unique RefSeq proteins for LMP007523 (as displayed in Record Overview)
Identical Sequences to LMP007523 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:6324571 | GenBank | EDN63868.1 | 378 | palmitoyltransferase [Saccharomyces cerevisiae YJM789] |
| GI:6324571 | GenBank | EDV10606.1 | 378 | palmitoyltransferase [Saccharomyces cerevisiae RM11-1a] |
| GI:6324571 | GenBank | EGA73128.1 | 378 | Pfa4p [Saccharomyces cerevisiae AWRI796] |
| GI:6324571 | GenBank | EGA84910.1 | 378 | Pfa4p [Saccharomyces cerevisiae VL3] |
| GI:6324571 | GenBank | EWG93457.1 | 378 | Pfa4p [Saccharomyces cerevisiae R103] |
| GI:6324571 | Third Party Genbank | DAA10780.1 | 378 | TPA: Pfa4p [Saccharomyces cerevisiae S288c] |
Related Sequences to LMP007523 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:6324571 | DBBJ | GAA26321.1 | 378 | K7_Pfa4p [Saccharomyces cerevisiae Kyokai no. 7] |
| GI:6324571 | GenBank | EEU08924.1 | 378 | Pfa4p [Saccharomyces cerevisiae JAY291] |
| GI:6324571 | GenBank | EGA76982.1 | 378 | Pfa4p [Saccharomyces cerevisiae Vin13] |
| GI:6324571 | GenBank | EIW07432.1 | 378 | Pfa4p [Saccharomyces cerevisiae CEN.PK113-7D] |
| GI:6324571 | GenBank | EWH15854.1 | 378 | Pfa4p [Saccharomyces cerevisiae P283] |
| GI:6324571 | gnl | McCuskerlabDuke | 378 | Pfa4p [Saccharomyces cerevisiae YJM993] |