Gene/Proteome Database (LMPD)

LMPD ID
LMP007579
Gene ID
Species
Escherichia coli K-12 (E. coli)
Gene Name
lipoprotein-releasing system transmembrane protein
Gene Symbol
Synonyms
ECK1104; JW1104; ycfW
Summary
LolE is a membrane component of the LolCDE lipoprotein export ABC transporter. [More information is available at EcoCyc: G6575].
Orthologs

Proteins

lipoprotein-releasing system transmembrane protein [Escherichia coli str. K-12 substr. MG1655]
Refseq ID NP_415636
Protein GI 16129081
UniProt ID P75958
Length 414
RefSeq Status REVIEWED
MAMPLSLLIGLRFSRGRRRGGMVSLISVISTIGIALGVAVLIVGLSAMNGFERELNNRILAVVPHGEIEAVDQPWTNWQEALDHVQKVPGIAAAAPYINFTGLVESGANLRAIQVKGVNPQQEQRLSALPSFVQGDAWRNFKAGEQQIIIGKGVADALKVKQGDWVSIMIPNSNPEHKLMQPKRVRLHVAGILQLSGQLDHSFAMIPLADAQQYLDMGSSVSGIALKMTDVFNANKLVRDAGEVTNSYVYIKSWIGTYGYMYRDIQMIRAIMYLAMVLVIGVACFNIVSTLVMAVKDKSGDIAVLRTLGAKDGLIRAIFVWYGLLAGLFGSLCGVIIGVVVSLQLTPIIEWIEKLIGHQFLSSDIYFIDFLPSELHWLDVFYVLVTALLLSLLASWYPARRASNIDPARVLSGQ

Gene Information

Entrez Gene ID
Gene Name
lipoprotein-releasing system transmembrane protein
Gene Symbol
Species
Escherichia coli K-12

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0009276 IEA:InterPro C Gram-negative-bacterium-type cell wall
GO:0005887 IDA:EcoCyc C integral component of plasma membrane
GO:0043234 IDA:EcoCyc C protein complex
GO:0042954 IDA:EcoCyc F lipoprotein transporter activity
GO:0042953 IDA:EcoCyc P lipoprotein transport

KEGG Pathway Links

KEGG Pathway ID Description
eco02010 ABC transporters
ko02010 ABC transporters
eco_M00255 Lipoprotein-releasing system
M00255 Lipoprotein-releasing system

Domain Information

InterPro Annotations

Accession Description
IPR011925 LolCE_TM
IPR011926 LolE_TM
IPR025857 MacB_PCD
IPR003838 Permease_FtsX-like

UniProt Annotations

Entry Information

Gene Name
lipoprotein-releasing system transmembrane protein
Protein Entry
LOLE_ECOLI
UniProt ID
Species
E. coli

Comments

Comment Type Description
Function Part of an ATP-dependent transport system LolCDE responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and of LolA.
Interaction P0A912:pal; NbExp=2; IntAct=EBI-1125190, EBI-1124760;
Similarity Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily. {ECO:0000305}.
Subcellular Location Cell inner membrane; Multi-pass membrane protein.

Identical and Related Proteins

Unique RefSeq proteins for LMP007579 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
16129081 RefSeq NP_415636 414 lipoprotein-releasing system transmembrane protein [Escherichia coli str. K-12 substr. MG1655]

Identical Sequences to LMP007579 proteins

Reference Database Accession Length Protein Name
GI:16129081 GenBank KHI72874.1 414 outer membrane-specific lipoprotein transporter subunit LolE [Escherichia coli]
GI:16129081 GenBank KHI82672.1 414 outer membrane-specific lipoprotein transporter subunit LolE [Escherichia coli]
GI:16129081 GenBank KHI95001.1 414 outer membrane-specific lipoprotein transporter subunit LolE [Escherichia coli]
GI:16129081 GenBank KHJ10615.1 414 outer membrane-specific lipoprotein transporter subunit LolE [Escherichia coli]
GI:16129081 GenBank KHJ17544.1 414 outer membrane-specific lipoprotein transporter subunit LolE [Escherichia coli]
GI:16129081 gnl IGS 414 lipoprotein-releasing system transmembrane protein [Escherichia coli ER2796]

Related Sequences to LMP007579 proteins

Reference Database Accession Length Protein Name
GI:16129081 GenBank EGJ05392.1 414 lipoprotein releasing system, transmembrane protein LolE [Escherichia coli D9]
GI:16129081 GenBank EZB26844.1 414 outer membrane-specific lipoprotein transporter subunit LolE [Escherichia coli O169:H41 str. F9792]
GI:16129081 GenBank KDV47425.1 414 outer membrane-specific lipoprotein transporter subunit LolE [Escherichia coli O91:H21 str. 2009C-3740]
GI:16129081 RefSeq WP_001251349.1 414 transporter [Escherichia coli]
GI:16129081 RefSeq WP_024171465.1 414 outer membrane-specific lipoprotein transporter subunit LolE [Escherichia coli]
GI:16129081 RefSeq WP_024192457.1 414 outer membrane-specific lipoprotein transporter subunit LolE [Escherichia coli]