Gene/Proteome Database (LMPD)

LMPD ID
LMP007592
Gene ID
948136
Species
Escherichia coli K-12 (E. coli)
Gene Name
ADP-heptose:LPS heptosyl transferase I
Gene Symbol
waaC
Synonyms
ECK3611; JW3596; rfaC; yibC
Summary
Overexpression causes abnormal biofilm architecture. [More information is available at EcoGene: EG11189]. The lipopolysaccharide of Escherichia coli K-12 consists of two major components: the hydrophobic lipid A moiety inserted into the outer membrane and the phosphorylated core oligosaccharide . [More information is available at EcoCyc: EG11189].
Orthologs
View orthologs and multiple alignments for waaC

Proteins

ADP-heptose:LPS heptosyl transferase I [Escherichia coli str. K-12 substr. MG1655]
Refseq ID NP_418078
Protein GI 16131492
UniProt ID P24173
Length 319
RefSeq Status REVIEWED
MRVLIVKTSSMGDVLHTLPALTDAQQAIPGIKFDWVVEEGFAQIPSWHAAVERVIPVAIRRWRKAWFSAPIKAERKAFREALQAENYDAVIDAQGLVKSAALVTRLAHGVKHGMDWQTAREPLASLFYNRKHHIAKQQHAVERTRELFAKSLGYSKPQTQGDYAIAQHFLTNLPTDAGEYAVFLHATTRDDKHWPEEHWRELIGLLADSGIRIKLPWGAPHEEERAKRLAEGFAYVEVLPKMSLEGVARVLAGAKFVVSVDTGLSHLTAALDRPNITVYGPTDPGLIGGYGKNQMVCRAPRENLINLNSQAVLEKLSSL

Gene Information

Entrez Gene ID
948136
Gene Name
ADP-heptose:LPS heptosyl transferase I
Gene Symbol
waaC
Species
Escherichia coli K-12

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0008920 IDA:CACAO F lipopolysaccharide heptosyltransferase activity
GO:0009244 IMP:CACAO P lipopolysaccharide core region biosynthetic process

KEGG Pathway Links

KEGG Pathway ID Description
eco00540 Lipopolysaccharide biosynthesis
ko00540 Lipopolysaccharide biosynthesis
eco01100 Metabolic pathways

BIOCYC Pathway Links

BIOCYC Pathway ID Description
LIPA-CORESYN-PWY Lipid A-core biosynthesis
LIPA-CORESYN-PWY Lipid A-core biosynthesis
LPSSYN-PWY superpathway of lipopolysaccharide biosynthesis
LPSSYN-PWY superpathway of lipopolysaccharide biosynthesis

Domain Information

InterPro Annotations

Accession Description
IPR002201 Glyco_trans_9
IPR011908 LipoPS_heptosylTferase-I

UniProt Annotations

Entry Information

Gene Name
ADP-heptose:LPS heptosyl transferase I
Protein Entry
RFAC_ECOLI
UniProt ID
P24173
Species
E. coli

Comments

Comment Type Description
Function Heptose transfer to the lipopolysaccharide core. It transfers the innermost heptose to [4'-P](3-deoxy-D-manno- octulosonic acid)2-IVA.
Pathway Bacterial outer membrane biogenesis; LPS core biosynthesis.
Similarity Belongs to the glycosyltransferase 9 family. {ECO:0000305}.

Identical and Related Proteins

Unique RefSeq proteins for LMP007592 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
16131492 RefSeq NP_418078 319 ADP-heptose:LPS heptosyl transferase I [Escherichia coli str. K-12 substr. MG1655]

Identical Sequences to LMP007592 proteins

Reference Database Accession Length Protein Name
GI:16131492 EMBL CDZ22399.1 319 ADP-heptose:LPS heptosyltransferase I [Escherichia coli]
GI:16131492 GenBank KGL69995.1 319 ADP-heptose:LPS heptosyl transferase I [Escherichia coli NCTC 50110]
GI:16131492 GenBank KGM67020.1 319 ADP-heptose:LPS heptosyl transferase I [Escherichia coli]
GI:16131492 GenBank KGM76141.1 319 ADP-heptose:LPS heptosyl transferase I [Escherichia coli]
GI:16131492 GenBank KHH63978.1 319 ADP-heptose--LPS heptosyltransferase [Escherichia coli]
GI:16131492 gnl IGS 319 ADP-heptose:LPS heptosyl transferase I [Escherichia coli ER2796]

Related Sequences to LMP007592 proteins

Reference Database Accession Length Protein Name
GI:16131492 GenBank KDF72284.1 319 lipopolysaccharide heptosyltransferase 1 [Escherichia coli BIDMC 58]
GI:16131492 GenBank KDF83721.1 319 lipopolysaccharide heptosyltransferase 1 [Escherichia coli BIDMC 62]
GI:16131492 GenBank KDF84768.1 319 lipopolysaccharide heptosyltransferase 1 [Escherichia coli BIDMC 64]
GI:16131492 GenBank KDF85623.1 319 lipopolysaccharide heptosyltransferase 1 [Escherichia coli BIDMC 63]
GI:16131492 GenBank KDG00399.1 319 lipopolysaccharide heptosyltransferase 1 [Escherichia coli BIDMC 70]
GI:16131492 GenBank KDG25373.1 319 lipopolysaccharide heptosyltransferase 1 [Escherichia coli BIDMC 76]