Gene/Proteome Database (LMPD)

LMPD ID
LMP007596
Gene ID
948155
Species
Escherichia coli K-12 (E. coli)
Gene Name
lipopolysaccharide core biosynthesis protein
Gene Symbol
waaQ
Synonyms
ECK3622; JW3607; rfaQ
Summary
The lipopolysaccharide of Escherichia coli K-12 consists of two major components: the hydrophobic lipid A moiety inserted into the outer membrane and the phosphorylated core oligosaccharide . [More information is available at EcoCyc: EG11341].
Orthologs
View orthologs and multiple alignments for waaQ

Proteins

lipopolysaccharide core biosynthesis protein [Escherichia coli str. K-12 substr. MG1655]
Refseq ID NP_418089
Protein GI 16131503
UniProt ID P25742
Length 344
RefSeq Status REVIEWED
MRYHGDMLLTTPVISTLKQNYPDAKIDMLLYQDTIPILSENPEINALYGISNKGAGTFDKIKNVLSLIKTLRANNYDLVINLTDQWMVALLVRCLPARMKISQLYGHRQHGIWKKSFTHLAPIHGTHIVERNLSVLEPLGITDFYTDTTMSYAEDCWKKMRRELDALGVKDHYVVIQPTARQIFKCWDNDKFSKVIDALQQRGYQVVLTCGPSADDLACVDEIARGCETKPITGLAGKTRFPELGALIDHAVLFIGVDSAPGHIAAAVKTPVISLFGATDHVFWRPWTENIIQFWAGNYQKMPTRHELDRNKKYLSVIPAEDVIAATEKLLPEDAPSADRNAQL

Gene Information

Entrez Gene ID
948155
Gene Name
lipopolysaccharide core biosynthesis protein
Gene Symbol
waaQ
Species
Escherichia coli K-12

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0016740 IMP:EcoCyc F transferase activity
GO:0016757 IEA:UniProtKB-KW F transferase activity, transferring glycosyl groups
GO:0009244 IMP:EcoCyc P lipopolysaccharide core region biosynthetic process

KEGG Pathway Links

KEGG Pathway ID Description
eco00540 Lipopolysaccharide biosynthesis
ko00540 Lipopolysaccharide biosynthesis
eco01100 Metabolic pathways

BIOCYC Pathway Links

BIOCYC Pathway ID Description
LIPA-CORESYN-PWY Lipid A-core biosynthesis
LIPA-CORESYN-PWY Lipid A-core biosynthesis
LPSSYN-PWY superpathway of lipopolysaccharide biosynthesis
LPSSYN-PWY superpathway of lipopolysaccharide biosynthesis

Domain Information

InterPro Annotations

Accession Description
IPR002201 Glyco_trans_9
IPR011916 LipoPS_heptosylTferase-III

UniProt Annotations

Entry Information

Gene Name
lipopolysaccharide core biosynthesis protein
Protein Entry
RFAQ_ECOLI
UniProt ID
P25742
Species
E. coli

Comments

Comment Type Description
Function Catalyzes heptose transfer to the lipopolysaccharide core. It transfers a heptose, called heptose(III), to the heptose(II) of the inner core (By similarity). {ECO:0000250}.
Interaction P0A6F5:groL; NbExp=1; IntAct=EBI-555525, EBI-543750;
Pathway Bacterial outer membrane biogenesis; LPS core biosynthesis.
Similarity Belongs to the glycosyltransferase 9 family. {ECO:0000305}.

Identical and Related Proteins

Unique RefSeq proteins for LMP007596 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
16131503 RefSeq NP_418089 344 lipopolysaccharide core biosynthesis protein [Escherichia coli str. K-12 substr. MG1655]

Identical Sequences to LMP007596 proteins

Reference Database Accession Length Protein Name
GI:16131503 EMBL CDZ22410.1 344 lipopolysaccharide core heptosyl transferase III [Escherichia coli]
GI:16131503 GenBank KGL70286.1 344 lipopolysaccharide core heptosyltransferase RfaQ [Escherichia coli NCTC 50110]
GI:16131503 GenBank KGM67009.1 344 Lipopolysaccharide core biosynthesis protein [Escherichia coli]
GI:16131503 GenBank KGM76130.1 344 Lipopolysaccharide core biosynthesis protein [Escherichia coli]
GI:16131503 GenBank KHH67008.1 344 lipopolysaccharide core heptosyltransferase RfaQ [Escherichia coli]
GI:16131503 gnl IGS 344 lipopolysaccharide core biosynthesis protein [Escherichia coli ER2796]

Related Sequences to LMP007596 proteins

Reference Database Accession Length Protein Name
GI:16131503 GenBank AAC69658.1 344 WaaQ [Escherichia coli]
GI:16131503 GenBank EIL65201.1 344 lipopolysaccharide core biosynthesis protein [Escherichia coli 75]
GI:16131503 GenBank EQY95582.1 356 lipopolysaccharide core heptosyltransferase rfaQ [Escherichia coli UMEA 3318-1]
GI:16131503 GenBank EST79922.1 344 lipopolysaccharide core biosynthesis protein [Escherichia coli ECA-727]
GI:16131503 RefSeq WP_001268852.1 344 lipopolysaccharide core heptosyltransferase RfaQ [Escherichia coli]
GI:16131503 RefSeq WP_032143838.1 344 lipopolysaccharide core heptosyltransferase RfaQ [Escherichia coli]