Gene/Proteome Database (LMPD)

LMPD ID
LMP007599
Gene ID
947303
Species
Escherichia coli K-12 (E. coli)
Gene Name
phosphatidylglycerol-prolipoprotein diacylglyceryl transferase
Gene Symbol
lgt
Synonyms
ECK2824; JW2796; umpA
Summary
Sequence analysis, mutation, and expression studies show that lgt and the gene immediately downstream, thyA, form an operon . [More information is available at EcoCyc: EG12128].
Orthologs
View orthologs and multiple alignments for lgt

Proteins

phosphatidylglycerol-prolipoprotein diacylglyceryl transferase [Escherichia coli str. K-12 substr. MG1655]
Refseq ID NP_417305
Protein GI 16130732
UniProt ID P60955
Length 291
RefSeq Status REVIEWED
MTSSYLHFPEFDPVIFSIGPVALHWYGLMYLVGFIFAMWLATRRANRPGSGWTKNEVENLLYAGFLGVFLGGRIGYVLFYNFPQFMADPLYLFRVWDGGMSFHGGLIGVIVVMIIFARRTKRSFFQVSDFIAPLIPFGLGAGRLGNFINGELWGRVDPNFPFAMLFPGSRTEDILLLQTNPQWQSIFDTYGVLPRHPSQLYELLLEGVVLFIILNLYIRKPRPMGAVSGLFLIGYGAFRIIVEFFRQPDAQFTGAWVQYISMGQILSIPMIVAGVIMMVWAYRRSPQQHVS

Gene Information

Entrez Gene ID
947303
Gene Name
phosphatidylglycerol-prolipoprotein diacylglyceryl transferase
Gene Symbol
lgt
Species
Escherichia coli K-12

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0016021 IDA:EcoCyc C integral component of membrane
GO:0005887 IDA:EcoCyc C integral component of plasma membrane
GO:0008961 IDA:EcoCyc F phosphatidylglycerol-prolipoprotein diacylglyceryl transferase activity
GO:0042158 IDA:EcoCyc P lipoprotein biosynthetic process
GO:0009249 IEA:InterPro P protein lipoylation

Domain Information

InterPro Annotations

Accession Description
IPR001640 Prolipoprot_diAcglycer_Trfase

UniProt Annotations

Entry Information

Gene Name
phosphatidylglycerol-prolipoprotein diacylglyceryl transferase
Protein Entry
LGT_ECOLI
UniProt ID
P60955
Species
E. coli

Comments

Comment Type Description
Disruption Phenotype Mutants are defective in diacylglyceryl modification of prolipoprotein. {ECO:0000269|PubMed:22287519, ECO:0000269|PubMed:7896715}.
Function Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins. {ECO:0000269|PubMed:8051048}.
Pathway Protein modification; lipoprotein biosynthesis (diacylglyceryl transfer). {ECO:0000269|PubMed:7896715, ECO:0000269|PubMed:8051048}.
Similarity Belongs to the Lgt family. {ECO:0000305}.
Subcellular Location Cell inner membrane {ECO:0000269|PubMed:15919996, ECO:0000269|PubMed:22287519}; Multi- pass membrane protein {ECO:0000269|PubMed:22287519}.

Identical and Related Proteins

Unique RefSeq proteins for LMP007599 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
16130732 RefSeq NP_417305 291 phosphatidylglycerol-prolipoprotein diacylglyceryl transferase [Escherichia coli str. K-12 substr. MG1655]

Identical Sequences to LMP007599 proteins

Reference Database Accession Length Protein Name
GI:16130732 GenBank KHJ09100.1 291 diacylglyceryl transferase [Escherichia coli]
GI:16130732 GenBank KHJ10560.1 291 diacylglyceryl transferase [Escherichia coli]
GI:16130732 GenBank KHJ20074.1 291 diacylglyceryl transferase [Escherichia coli]
GI:16130732 GenBank KHJ21700.1 291 diacylglyceryl transferase [Escherichia coli]
GI:16130732 GenBank KHJ23356.1 291 diacylglyceryl transferase [Escherichia coli]
GI:16130732 gnl IGS 291 phosphatidylglycerol-prolipoprotein diacylglyceryl transferase [Escherichia coli ER2796]

Related Sequences to LMP007599 proteins

Reference Database Accession Length Protein Name
GI:16130732 GenBank EMX83080.1 291 prolipoprotein diacylglyceryl transferase [Escherichia coli 2719100]
GI:16130732 GenBank ENA38643.1 291 prolipoprotein diacylglyceryl transferase [Escherichia coli P0301867.4]
GI:16130732 GenBank END56894.1 291 prolipoprotein diacylglyceryl transferase [Escherichia coli BCE006_MS-23]
GI:16130732 GenBank KEN47003.1 291 prolipoprotein diacylglyceryl transferase [Escherichia coli 6-537-08_S1_C2]
GI:16130732 GenBank KEN54490.1 291 prolipoprotein diacylglyceryl transferase [Escherichia coli 6-537-08_S1_C3]
GI:16130732 RefSeq WP_001508884.1 291 prolipoprotein diacylglyceryl transferase [Escherichia coli]