Gene/Proteome Database (LMPD)

LMPD ID
LMP007709
Gene ID
946733
Species
Escherichia coli K-12 (E. coli)
Gene Name
anaerobic sn-glycerol-3-phosphate dehydrogenase membrane anchor subunit
Gene Symbol
glpB
Synonyms
ECK2234; JW2236; glpC; psi-51
Summary
The GlpABC enzyme is loosely associated with the cell membrane. [More information is available at EcoCyc: EG10392].
Orthologs
View orthologs and multiple alignments for glpB

Proteins

anaerobic sn-glycerol-3-phosphate dehydrogenase membrane anchor subunit [Escherichia coli str. K-12 substr. MG1655]
Refseq ID NP_416745
Protein GI 16130177
UniProt ID P13033
Length 419
RefSeq Status REVIEWED
MRFDTVIMGGGLAGLLCGLQLQKHGLRCAIVTRGQSALHFSSGSLDLLSHLPDGQPVTDIHSGLESLRQQAPAHPYSLLEPQRVLDLACQAQALIAESGAQLQGSVELAHQRVTPLGTLRSTWLSSPEVPVWPLPAKKICVVGISGLMDFQAHLAAASLRELGLAVETAEIELPELDVLRNNATEFRAVNIARFLDNEENWPLLLDALIPVANTCEMILMPACFGLADDKLWRWLNEKLPCSLMLLPTLPPSVLGIRLQNQLQRQFVRQGGVWMPGDEVKKVTCKNGVVNEIWTRNHADIPLRPRFAVLASGSFFSGGLVAERNGIREPILGLDVLQTATRGEWYKGDFFAPQPWQQFGVTTDETLRPSQAGQTIENLFAIGSVLGGFDPIAQGCGGGVCAVSALHAAQQIAQRAGGQQ

Gene Information

Entrez Gene ID
946733
Gene Name
anaerobic sn-glycerol-3-phosphate dehydrogenase membrane anchor subunit
Gene Symbol
glpB
Species
Escherichia coli K-12

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005886 IDA:EcoCyc C plasma membrane
GO:0004368 IMP:EcoCyc F glycerol-3-phosphate dehydrogenase activity
GO:0052591 IEA:UniProtKB-EC F sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity
GO:0019563 IEA:UniProtKB-UniPathway P glycerol catabolic process

KEGG Pathway Links

KEGG Pathway ID Description
eco00564 Glycerophospholipid metabolism
ko00564 Glycerophospholipid metabolism

BIOCYC Pathway Links

BIOCYC Pathway ID Description
PWY0-381 glycerol and glycerophosphodiester degradation
PWY0-381 glycerol and glycerophosphodiester degradation
PWY-4261 glycerol degradation I
PWY-4261 glycerol degradation I
PWY-6952 glycerophosphodiester degradation
PWY-6952 glycerophosphodiester degradation

Domain Information

InterPro Annotations

Accession Description
IPR003953 FAD binding domain
IPR009158 G3P_DH_GlpB_su

UniProt Annotations

Entry Information

Gene Name
anaerobic sn-glycerol-3-phosphate dehydrogenase membrane anchor subunit
Protein Entry
GLPB_ECOLI
UniProt ID
P13033
Species
E. coli

Comments

Comment Type Description
Catalytic Activity sn-glycerol 3-phosphate + a quinone = glycerone phosphate + a quinol.
Cofactor Name=FMN; Xref=ChEBI:CHEBI:58210;
Function Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor.
Pathway Polyol metabolism; glycerol degradation via glycerol kinase pathway; glycerone phosphate from sn-glycerol 3-phosphate (anaerobic route): step 1/1.
Similarity Belongs to the anaerobic G-3-P dehydrogenase subunit B family. {ECO:0000305}.
Subcellular Location Cell inner membrane; Peripheral membrane protein. Note=Loosely bound to the cytoplasmic membrane often occurring in vesicles associated with fumarate reductase.
Subunit Composed of a catalytic GlpA/B dimer and of membrane bound GlpC.

Identical and Related Proteins

Unique RefSeq proteins for LMP007709 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
16130177 RefSeq NP_416745 419 anaerobic sn-glycerol-3-phosphate dehydrogenase membrane anchor subunit [Escherichia coli str. K-12 substr. MG1655]

Identical Sequences to LMP007709 proteins

Reference Database Accession Length Protein Name
GI:16130177 GenBank KHI15542.1 419 glycerol-3-phosphate dehydrogenase [Escherichia coli]
GI:16130177 GenBank KHI19765.1 419 glycerol-3-phosphate dehydrogenase [Escherichia coli]
GI:16130177 GenBank KHI59994.1 419 glycerol-3-phosphate dehydrogenase [Escherichia coli]
GI:16130177 GenBank KHI82376.1 419 glycerol-3-phosphate dehydrogenase [Escherichia coli]
GI:16130177 GenBank KHI92650.1 419 glycerol-3-phosphate dehydrogenase [Escherichia coli]
GI:16130177 gnl IGS 419 sn-glycerol-3-phosphate dehydrogenase (anaerobic), membrane anchor subunit [Escherichia coli ER2796]

Related Sequences to LMP007709 proteins

Reference Database Accession Length Protein Name
GI:16130177 GenBank EGI11894.1 495 glycerol-3-phosphate dehydrogenase, anaerobic, B subunit [Escherichia coli H736]
GI:16130177 GenBank EYD85306.1 419 glycerol-3-phosphate dehydrogenase, anaerobic, B subunit [Escherichia coli 1-176-05_S1_C1]
GI:16130177 GenBank EZK07554.1 419 glycerol-3-phosphate dehydrogenase, anaerobic, B subunit [Escherichia coli 1-176-05_S1_C3]
GI:16130177 GenBank KEN55106.1 419 glycerol-3-phosphate dehydrogenase, anaerobic, B subunit [Escherichia coli 7-233-03_S4_C3]
GI:16130177 RefSeq WP_001209930.1 419 glycerol-3-phosphate dehydrogenase subunit B [Escherichia coli]
GI:16130177 RefSeq WP_032223585.1 419 glycerol-3-phosphate dehydrogenase [Escherichia coli]