Gene/Proteome Database (LMPD)

LMPD ID
LMP007720
Gene ID
947059
Species
Escherichia coli K-12 (E. coli)
Gene Name
phosphatidylserine synthase; CDP-diacylglycerol-serine O-phosphatidyltransferase
Gene Symbol
pssA
Synonyms
ECK2583; JW2569; pss
Summary
The enzyme is a multimer of unknown subunits. [More information is available at EcoCyc: EG10781].
Orthologs
View orthologs and multiple alignments for pssA

Proteins

phosphatidylserine synthase; CDP-diacylglycerol-serine O-phosphatidyltransferase [Escherichia coli str. K-12 substr. MG1655]
Refseq ID NP_417080
Protein GI 90111464
UniProt ID P23830
Length 451
RefSeq Status REVIEWED
MLSKFKRNKHQQHLAQLPKISQSVDDVDFFYAPADFRETLLEKIASAKQRICIVALYLEQDDGGKGILNALYEAKRQRPELDVRVLVDWHRAQRGRIGAAASNTNADWYCRMAQENPGVDVPVYGVPINTREALGVLHFKGFIIDDSVLYSGASLNDVYLHQHDKYRYDRYHLIRNRKMSDIMFEWVTQNIMNGRGVNRLDDVNRPKSPEIKNDIRLFRQELRDAAYHFQGDADNDQLSVTPLVGLGKSSLLNKTIFHLMPCAEQKLTICTPYFNLPAILVRNIIQLLREGKKVEIIVGDKTANDFYIPEDEPFKIIGALPYLYEINLRRFLSRLQYYVNTDQLVVRLWKDDDNTYHLKGMWVDDKWMLITGNNLNPRAWRLDLENAILIHDPQLELAPQREKELELIREHTTIVKHYRDLQSIADYPVKVRKLIRRLRRIRIDRLISRIL

Gene Information

Entrez Gene ID
947059
Gene Name
phosphatidylserine synthase; CDP-diacylglycerol-serine O-phosphatidyltransferase
Gene Symbol
pssA
Species
Escherichia coli K-12

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005737 IEA:UniProtKB-KW C cytoplasm
GO:0005886 IEA:UniProtKB-KW C plasma membrane
GO:0003882 IDA:EcoCyc F CDP-diacylglycerol-serine O-phosphatidyltransferase activity
GO:0008654 IEA:UniProtKB-KW P phospholipid biosynthetic process

KEGG Pathway Links

KEGG Pathway ID Description
eco00564 Glycerophospholipid metabolism
ko00564 Glycerophospholipid metabolism
eco00260 Glycine, serine and threonine metabolism
ko00260 Glycine, serine and threonine metabolism
eco01100 Metabolic pathways
M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE
eco_M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE

BIOCYC Pathway Links

BIOCYC Pathway ID Description
PWY-5669 phosphatidylethanolamine biosynthesis I
PWY-5669 phosphatidylethanolamine biosynthesis I
PWY-5669 phosphatidylethanolamine biosynthesis I
PHOSLIPSYN-PWY phospholipid biosynthesis I
PHOSLIPSYN-PWY phospholipid biosynthesis I
PHOSLIPSYN-PWY phospholipid biosynthesis I

Domain Information

InterPro Annotations

Accession Description
IPR016270 Phospholipase D, phosphatidylserine synthase type
IPR001736 Phospholipase D/Transphosphatidylase

UniProt Annotations

Entry Information

Gene Name
phosphatidylserine synthase; CDP-diacylglycerol-serine O-phosphatidyltransferase
Protein Entry
PSS_ECOLI
UniProt ID
P23830
Species
E. coli

Comments

Comment Type Description
Catalytic Activity CDP-diacylglycerol + L-serine = CMP + (3-sn- phosphatidyl)-L-serine.
Similarity Belongs to the CDP-alcohol phosphatidyltransferase class-II family. {ECO:0000305}.
Similarity Contains 2 PLD phosphodiesterase domains. {ECO:0000255|PROSITE-ProRule:PRU00153}.
Subcellular Location Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Subunit Multimeric. Interacts with ACP, YbgC and PlsB, forming altogether a complex at the inner membrane. {ECO:0000269|PubMed:16294310}.

Identical and Related Proteins

Unique RefSeq proteins for LMP007720 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
90111464 RefSeq NP_417080 451 phosphatidylserine synthase; CDP-diacylglycerol-serine O-phosphatidyltransferase [Escherichia coli str. K-12 substr. MG1655]

Identical Sequences to LMP007720 proteins

Reference Database Accession Length Protein Name
GI:90111464 GenBank KHJ00069.1 451 phosphatidylserine synthase [Escherichia coli]
GI:90111464 GenBank KHJ01099.1 451 phosphatidylserine synthase [Escherichia coli]
GI:90111464 GenBank KHJ11217.1 451 phosphatidylserine synthase [Escherichia coli]
GI:90111464 GenBank KHJ11249.1 451 phosphatidylserine synthase [Escherichia coli]
GI:90111464 GenBank KHJ21970.1 451 phosphatidylserine synthase [Escherichia coli]
GI:90111464 gnl IGS 451 phosphatidylserine synthase (CDP-diacylglycerol-serine O-phosphatidyltransferase) [Escherichia coli ER2796]

Related Sequences to LMP007720 proteins

Reference Database Accession Length Protein Name
GI:90111464 DBBJ BAG78398.1 452 phosphatidylserine synthase [Escherichia coli SE11]
GI:90111464 GenBank ACI79676.1 452 phosphatidylserine synthase [Escherichia coli]
GI:90111464 GenBank ACI79677.1 452 phosphatidylserine synthase [Escherichia coli]
GI:90111464 GenBank ACI79678.1 452 phosphatidylserine synthase [Escherichia coli]
GI:90111464 GenBank ACI79679.1 452 phosphatidylserine synthase [Escherichia coli]
GI:90111464 RefSeq YP_002294149.1 452 phosphatidylserine synthase [Escherichia coli SE11]