Gene/Proteome Database (LMPD)

LMPD ID
LMP007726
Gene ID
948410
Species
Escherichia coli K-12 (E. coli)
Gene Name
CDP-diacylglycerol phosphotidylhydrolase
Gene Symbol
cdh
Synonyms
ECK3910; JW3889; pnuE; ushB
Summary
It is unclear if Cdh(E.c.) has UshB or PnuE activity. [More information is available at EcoGene: EG10138].
Orthologs
View orthologs and multiple alignments for cdh

Proteins

CDP-diacylglycerol phosphotidylhydrolase [Escherichia coli str. K-12 substr. MG1655]
Refseq ID NP_418353
Protein GI 16131756
UniProt ID P06282
Length 251
RefSeq Status REVIEWED
MKKAGLLFLVMIVIAVVAAGIGYWKLTGEESDTLRKIVLEECLPNQQQNQNPSPCAEVKPNAGYVVLKDLNGPLQYLLMPTYRINGTESPLLTDPSTPNFFWLAWQARDFMSKKYGQPVPDRAVSLAINSRTGRTQNHFHIHISCIRPDVRKQLDNNLANISSRWLPLPGGLRGHEYLARRVTESELVQRSPFMMLAEEVPEAREHMGRYGLAMVRQSDNSFVLLATQRNLLTLNRASAEEIQDHQCEILR

Gene Information

Entrez Gene ID
948410
Gene Name
CDP-diacylglycerol phosphotidylhydrolase
Gene Symbol
cdh
Species
Escherichia coli K-12

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0005886 IEA:UniProtKB-HAMAP C plasma membrane
GO:0008715 IDA:EcoCyc F CDP-diacylglycerol diphosphatase activity
GO:0046342 IMP:EcoCyc P CDP-diacylglycerol catabolic process
GO:0008654 IEA:UniProtKB-HAMAP P phospholipid biosynthetic process

KEGG Pathway Links

KEGG Pathway ID Description
eco00564 Glycerophospholipid metabolism
ko00564 Glycerophospholipid metabolism

Domain Information

InterPro Annotations

Accession Description
IPR003763 CDP-diacylglyc_Pase
IPR015993 CDP-diacylglyc_Pase_proteobac
IPR011146 HIT-like

UniProt Annotations

Entry Information

Gene Name
CDP-diacylglycerol phosphotidylhydrolase
Protein Entry
CDH_ECOLI
UniProt ID
P06282
Species
E. coli

Comments

Comment Type Description
Catalytic Activity CDP-diacylglycerol + H(2)O = CMP + phosphatidate.
Pathway Phospholipid metabolism; CDP-diacylglycerol degradation; phosphatidate from CDP-diacylglycerol: step 1/1.
Sequence Caution Sequence=CAA26358.1; Type=Frameshift; Positions=Several; Evidence={ECO:0000305};
Similarity Belongs to the Cdh family. {ECO:0000305}.
Subcellular Location Cell inner membrane; Single-pass membrane protein.

Identical and Related Proteins

Unique RefSeq proteins for LMP007726 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
16131756 RefSeq NP_418353 251 CDP-diacylglycerol phosphotidylhydrolase [Escherichia coli str. K-12 substr. MG1655]

Identical Sequences to LMP007726 proteins

Reference Database Accession Length Protein Name
GI:16131756 GenBank KHH69842.1 251 CDP-diacylglycerol pyrophosphatase [Escherichia coli]
GI:16131756 GenBank KHH90418.1 251 CDP-diacylglycerol pyrophosphatase [Escherichia coli]
GI:16131756 GenBank KHI13508.1 251 CDP-diacylglycerol pyrophosphatase [Escherichia coli]
GI:16131756 GenBank KHI14961.1 251 CDP-diacylglycerol pyrophosphatase [Escherichia coli]
GI:16131756 GenBank KHI55916.1 251 CDP-diacylglycerol pyrophosphatase [Escherichia coli]
GI:16131756 gnl IGS 251 CDP-diacylglycerol phosphotidylhydrolase [Escherichia coli ER2796]

Related Sequences to LMP007726 proteins

Reference Database Accession Length Protein Name
GI:16131756 GenBank END88252.1 251 CDP-diacylglycerol pyrophosphatase [Escherichia coli P0301904.3]
GI:16131756 GenBank ENE04167.1 251 CDP-diacylglycerol pyrophosphatase [Escherichia coli P0305260.2]
GI:16131756 GenBank KGP10782.1 251 CDP-diacylglycerol pyrophosphatase [Escherichia coli]
GI:16131756 GenBank KGP15441.1 251 CDP-diacylglycerol pyrophosphatase [Escherichia coli]
GI:16131756 GenBank KGP19893.1 251 CDP-diacylglycerol pyrophosphatase [Escherichia coli]
GI:16131756 RefSeq WP_033801328.1 251 CDP-diacylglycerol pyrophosphatase [Escherichia coli]