Gene/Proteome Database (LMPD)

LMPD ID
LMP007763
Gene ID
944876
Species
Escherichia coli K-12 (E. coli)
Gene Name
CDP-diglyceride synthase
Gene Symbol
cdsA
Synonyms
ECK0174; JW5810
Summary
CdsA binds RNaseE. [More information is available at EcoGene: EG10139].
Orthologs
View orthologs and multiple alignments for cdsA

Proteins

CDP-diglyceride synthase [Escherichia coli str. K-12 substr. MG1655]
Refseq ID NP_414717
Protein GI 90111095
UniProt ID P0ABG1
Length 285
RefSeq Status REVIEWED
MLKYRLISAFVLIPVVIAALFLLPPVGFAIVTLVVCMLAAWEWGQLSGFTTRSQRVWLAVLCGLLLALMLFLLPEYHRNIHQPLVEISLWASLGWWIVALLLVLFYPGSAAIWRNSKTLRLIFGVLTIVPFFWGMLALRAWHYDENHYSGAIWLLYVMILVWGADSGAYMFGKLFGKHKLAPKVSPGKTWQGFIGGLATAAVISWGYGMWANLDVAPVTLLICSIVAALASVLGDLTESMFKREAGIKDSGHLIPGHGGILDRIDSLTAAVPVFACLLLLVFRTL

Gene Information

Entrez Gene ID
944876
Gene Name
CDP-diglyceride synthase
Gene Symbol
cdsA
Species
Escherichia coli K-12

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0005886 IDA:EcoCyc C plasma membrane
GO:0004605 IDA:EcoCyc F phosphatidate cytidylyltransferase activity
GO:0016024 IDA:EcoCyc P CDP-diacylglycerol biosynthetic process

KEGG Pathway Links

KEGG Pathway ID Description
eco00564 Glycerophospholipid metabolism
ko00564 Glycerophospholipid metabolism
eco01100 Metabolic pathways
M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE
eco_M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE

BIOCYC Pathway Links

BIOCYC Pathway ID Description
PWY-5667 CDP-diacylglycerol biosynthesis I
PWY-5667 CDP-diacylglycerol biosynthesis I
PWY-5667 CDP-diacylglycerol biosynthesis I
PWY0-1319 CDP-diacylglycerol biosynthesis II
PWY0-1319 CDP-diacylglycerol biosynthesis II
PWY0-1319 CDP-diacylglycerol biosynthesis II
PWY4FS-7 phosphatidylglycerol biosynthesis I (plastidic)
PWY4FS-8 phosphatidylglycerol biosynthesis II (non-plastidic)
PHOSLIPSYN-PWY phospholipid biosynthesis I
PHOSLIPSYN-PWY phospholipid biosynthesis I
PHOSLIPSYN-PWY phospholipid biosynthesis I

Domain Information

InterPro Annotations

Accession Description
IPR000374 Phosphatidate cytidylyltransferase

UniProt Annotations

Entry Information

Gene Name
CDP-diglyceride synthase
Protein Entry
CDSA_ECOLI
UniProt ID
P0ABG1
Species
E. coli

Comments

Comment Type Description
Catalytic Activity CTP + phosphatidate = diphosphate + CDP- diacylglycerol.
Pathway Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 3/3.
Sequence Caution Sequence=AAA23545.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAB08604.1; Type=Erroneous initiation; Evidence={ECO:0000305};
Similarity Belongs to the CDS family. {ECO:0000305}.
Subcellular Location Cell inner membrane; Multi-pass membrane protein.

Identical and Related Proteins

Unique RefSeq proteins for LMP007763 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
90111095 RefSeq NP_414717 285 CDP-diglyceride synthase [Escherichia coli str. K-12 substr. MG1655]

Identical Sequences to LMP007763 proteins

Reference Database Accession Length Protein Name
GI:90111095 GenBank KHI95630.1 285 CDP-diglyceride synthetase [Escherichia coli]
GI:90111095 GenBank KHJ05938.1 285 CDP-diglyceride synthetase [Escherichia coli]
GI:90111095 GenBank KHJ07576.1 285 CDP-diglyceride synthetase [Escherichia coli]
GI:90111095 GenBank KHJ15478.1 285 CDP-diglyceride synthetase [Escherichia coli]
GI:90111095 GenBank KHJ22932.1 285 CDP-diglyceride synthetase [Escherichia coli]
GI:90111095 gnl IGS 285 CDP-diglyceride synthase [Escherichia coli ER2796]

Related Sequences to LMP007763 proteins

Reference Database Accession Length Protein Name
GI:90111095 GenBank EGI33427.1 285 phosphatidate cytidylyltransferase [Escherichia coli TA143]
GI:90111095 GenBank EZJ80124.1 285 phosphatidate cytidylyltransferase [Escherichia coli 1-182-04_S3_C3]
GI:90111095 GenBank EZK04237.1 285 phosphatidate cytidylyltransferase [Escherichia coli 1-182-04_S3_C1]
GI:90111095 RefSeq WP_000922437.1 285 MULTISPECIES: CDP-diglyceride synthase [Escherichia]
GI:90111095 RefSeq WP_000922450.1 285 CDP-diglyceride synthase [Escherichia coli]
GI:90111095 RefSeq WP_032277838.1 285 CDP-diglyceride synthetase [Escherichia coli]