Gene/Proteome Database (LMPD)
Proteins
| Protein DGK-1, isoform a | |
|---|---|
| Refseq ID | NP_508191 |
| Protein GI | 17551330 |
| UniProt ID | Q7JNZ1 |
| mRNA ID | NM_075790 |
| Length | 950 |
| RefSeq Status | REVIEWED |
| MAAEGHNVDANLVDMRPNHGHYFVKKTFGKPAYCHHCCDKIWGMLTTGYSCEMCNFVCHEKCLRTVVSYCSSVALQLIKNPVAHTWSAPCLIKRKYCCVCRKRTDDALSVECEVCEYYVHVDCSDLAVSDCKEAATYVANMESANTVQYHHMREGNLPKESKCIVCRKTCFSTECLAGMRCEWCGQTAHAVCYRQMDKECDFGVLRKIMLPPMCLTIPRTELPMEQLLNISSHDQPQSLSSPSKIQADDVSTSGEDVKEREDFEIIRVFDGNNSYRSQISRNIVVAKHVSVQQVRDAALRRFHINDTPERYYITQVVGEVEEEILEDPVPLRNVKRPEGKRAQIFIRYYDDPDKDEVKVYGGWLRKVPVTFCAISVSKDTVVQDLVTDALYHFGLDGSCWNRYNLIEVSLDRGVAERTCNPQENVLQLVRNLRKDSLRRYHVVRFYVQEKEDPHDHAVFVGNLPVSLAQRQYERILLKLLGAKEKPFTAIGPIYFEYGSLIITFNTPKAATAAVQKLQSAIYEEKKLIVLCLPNVQPQMIPKDVEPLLVLVNVKSGGCQGTELIQSFRKLLNPFQVFDVLNGGPLVGLYVFRNIPKYKILACGGDGTIGWVLQCLDIAKQDAACFSPPCGIVPLGTGNDLARVLRWGGGYTGEENPMDILKDVIEADTVKLDRWAVVFHEEERNQPTSSGNQTEMNEQTMNNPEDQTSMIIMNNYFGIGIDADVCLKFHNKRDANPEKFQSRLFNKTQYAKIGLQKMFFERTCKDLWKRIELEVDGRIIELPNIEGIVVLNLLSWGSGANPWGTSKEEGNFSKPTHYDGLLEVVGISDVSRLGLIQSKLAAGIRIAQGGSIRITTHEEWPVQVDGEPHIQPPGTITILKSALKAQMLKKAKKSRRGGATNATSLTHPHPETSESMSGPLGVPSTLGDPNHGKTTPDNTAADSDEEGDAFL | |
| Protein DGK-1, isoform b | |
|---|---|
| Refseq ID | NP_508190 |
| Protein GI | 17551332 |
| UniProt ID | Q17860 |
| mRNA ID | NM_075789 |
| Length | 952 |
| RefSeq Status | REVIEWED |
| MAAEGHNVDANLVDMRPNHGHYFVKKTFGKPAYCHHCCDKIWGMLTTGYSCEMCNFVCHEKCLRTVVSYCSSVALQLIKNPVAHTWSAPCLIKRKYCCVCRKRTDDALSVECEVCEYYVHVDCSDLAVSDCKEAATYVANMESANTVQYHHMREGNLPKESKCIVCRKTCFSTECLAGMRCEWCGQTAHAVCYRQMDKECDFGVLRKIMLPPMCLTIPRTELPMEQLLNISSHDQPQSRKVSSPSKIQADDVSTSGEDVKEREDFEIIRVFDGNNSYRSQISRNIVVAKHVSVQQVRDAALRRFHINDTPERYYITQVVGEVEEEILEDPVPLRNVKRPEGKRAQIFIRYYDDPDKDEVKVYGGWLRKVPVTFCAISVSKDTVVQDLVTDALYHFGLDGSCWNRYNLIEVSLDRGVAERTCNPQENVLQLVRNLRKDSLRRYHVVRFYVQEKEDPHDHAVFVGNLPVSLAQRQYERILLKLLGAKEKPFTAIGPIYFEYGSLIITFNTPKAATAAVQKLQSAIYEEKKLIVLCLPNVQPQMIPKDVEPLLVLVNVKSGGCQGTELIQSFRKLLNPFQVFDVLNGGPLVGLYVFRNIPKYKILACGGDGTIGWVLQCLDIAKQDAACFSPPCGIVPLGTGNDLARVLRWGGGYTGEENPMDILKDVIEADTVKLDRWAVVFHEEERNQPTSSGNQTEMNEQTMNNPEDQTSMIIMNNYFGIGIDADVCLKFHNKRDANPEKFQSRLFNKTQYAKIGLQKMFFERTCKDLWKRIELEVDGRIIELPNIEGIVVLNLLSWGSGANPWGTSKEEGNFSKPTHYDGLLEVVGISDVSRLGLIQSKLAAGIRIAQGGSIRITTHEEWPVQVDGEPHIQPPGTITILKSALKAQMLKKAKKSRRGGATNATSLTHPHPETSESMSGPLGVPSTLGDPNHGKTTPDNTAADSDEEGDAFL | |
| Protein DGK-1, isoform c | |
|---|---|
| Refseq ID | NP_001024382 |
| Protein GI | 71982814 |
| UniProt ID | Q58AU6 |
| mRNA ID | NM_001029211 |
| Length | 794 |
| RefSeq Status | REVIEWED |
| MAAEGHNVDANLVDMRPNHGHYFVKKTFGKPAYCHHCCDKIWGMLTTGYSCEMCNFVCHEKCLRTVVSYCSSVALQLIKNPVAHTWSAPCLIKRKYCCVCRKRTDDALSVECEVCEYYVHVDCSDLAVSDCKEAATYVANMESANTVQYHHMREGNLPKESKCIVCRKTCFSTECLAGMRCEWCGQTAHAVCYRQMDKECDFGVLRKIMLPPMCLTIPRTELPMEQLLNISSHDQPQSLSSPSKIQADDVSTSGEDVKEREDFEIIRVFDGNNSYRSQDSLRRYHVVRFYVQEKEDPHDHAVFVGNLPVSLAQRQYERILLKLLGAKEKPFTAIGPIYFEYGSLIITFNTPKAATAAVQKLQSAIYEEKKLIVLCLPNVQPQMIPKDVEPLLVLVNVKSGGCQGTELIQSFRKLLNPFQVFDVLNGGPLVGLYVFRNIPKYKILACGGDGTIGWVLQCLDIAKQDAACFSPPCGIVPLGTGNDLARVLRWGGGYTGEENPMDILKDVIEADTVKLDRWAVVFHEEERNQPTSSGNQTEMNEQTMNNPEDQTSMIIMNNYFGIGIDADVCLKFHNKRDANPEKFQSRLFNKTQYAKIGLQKMFFERTCKDLWKRIELEVDGRIIELPNIEGIVVLNLLSWGSGANPWGTSKEEGNFSKPTHYDGLLEVVGISDVSRLGLIQSKLAAGIRIAQGGSIRITTHEEWPVQVDGEPHIQPPGTITILKSALKAQMLKKAKKSRRGGATNATSLTHPHPETSESMSGPLGVPSTLGDPNHGKTTPDNTAADSDEEGDAFL | |
| Protein DGK-1, isoform d | |
|---|---|
| Refseq ID | NP_001024383 |
| Protein GI | 71982823 |
| UniProt ID | Q58AU5 |
| mRNA ID | NM_001029212 |
| Length | 796 |
| RefSeq Status | REVIEWED |
| MAAEGHNVDANLVDMRPNHGHYFVKKTFGKPAYCHHCCDKIWGMLTTGYSCEMCNFVCHEKCLRTVVSYCSSVALQLIKNPVAHTWSAPCLIKRKYCCVCRKRTDDALSVECEVCEYYVHVDCSDLAVSDCKEAATYVANMESANTVQYHHMREGNLPKESKCIVCRKTCFSTECLAGMRCEWCGQTAHAVCYRQMDKECDFGVLRKIMLPPMCLTIPRTELPMEQLLNISSHDQPQSRKVSSPSKIQADDVSTSGEDVKEREDFEIIRVFDGNNSYRSQDSLRRYHVVRFYVQEKEDPHDHAVFVGNLPVSLAQRQYERILLKLLGAKEKPFTAIGPIYFEYGSLIITFNTPKAATAAVQKLQSAIYEEKKLIVLCLPNVQPQMIPKDVEPLLVLVNVKSGGCQGTELIQSFRKLLNPFQVFDVLNGGPLVGLYVFRNIPKYKILACGGDGTIGWVLQCLDIAKQDAACFSPPCGIVPLGTGNDLARVLRWGGGYTGEENPMDILKDVIEADTVKLDRWAVVFHEEERNQPTSSGNQTEMNEQTMNNPEDQTSMIIMNNYFGIGIDADVCLKFHNKRDANPEKFQSRLFNKTQYAKIGLQKMFFERTCKDLWKRIELEVDGRIIELPNIEGIVVLNLLSWGSGANPWGTSKEEGNFSKPTHYDGLLEVVGISDVSRLGLIQSKLAAGIRIAQGGSIRITTHEEWPVQVDGEPHIQPPGTITILKSALKAQMLKKAKKSRRGGATNATSLTHPHPETSESMSGPLGVPSTLGDPNHGKTTPDNTAADSDEEGDAFL | |
| Protein DGK-1, isoform e | |
|---|---|
| Refseq ID | NP_001024384 |
| Protein GI | 71982826 |
| UniProt ID | Q58AU4 |
| mRNA ID | NM_001029213 |
| Length | 919 |
| RefSeq Status | REVIEWED |
| MAAEGHNVDANLVDMRPNHGHYFVKKTFGKPAYCHHCCDKIWGMLTTGYSCEMCNFVCHEKCLRTVVSYCSSVALQLIKNPVAHTWSAPCLIKRKYCCVCRKRTDDALSVECEVCEYYVHVDCSDLAVSDCKEAATYVANMESANTVQYHHMREGNLPKESKCIVCRKTCFSTECLAGMRCEWCGQTAHAVCYRQMDKECDFGVLRKIMLPPMCLTIPRTELPMEQLLNISSHDQPQSRKGQIFHYPISRNIVVAKHVSVQQVRDAALRRFHINDTPERYYITQVVGEVEEEILEDPVPLRNVKRPEGKRAQIFIRYYDDPDKDEVKVYGGWLRKVPVTFCAISVSKDTVVQDLVTDALYHFGLDGSCWNRYNLIEVSLDRGVAERTCNPQENVLQLVRNLRKDSLRRYHVVRFYVQEKEDPHDHAVFVGNLPVSLAQRQYERILLKLLGAKEKPFTAIGPIYFEYGSLIITFNTPKAATAAVQKLQSAIYEEKKLIVLCLPNVQPQMIPKDVEPLLVLVNVKSGGCQGTELIQSFRKLLNPFQVFDVLNGGPLVGLYVFRNIPKYKILACGGDGTIGWVLQCLDIAKQDAACFSPPCGIVPLGTGNDLARVLRWGGGYTGEENPMDILKDVIEADTVKLDRWAVVFHEEERNQPTSSGNQTEMNEQTMNNPEDQTSMIIMNNYFGIGIDADVCLKFHNKRDANPEKFQSRLFNKTQYAKIGLQKMFFERTCKDLWKRIELEVDGRIIELPNIEGIVVLNLLSWGSGANPWGTSKEEGNFSKPTHYDGLLEVVGISDVSRLGLIQSKLAAGIRIAQGGSIRITTHEEWPVQVDGEPHIQPPGTITILKSALKAQMLKKAKKSRRGGATNATSLTHPHPETSESMSGPLGVPSTLGDPNHGKTTPDNTAADSDEEGDAFL | |
Gene Information
Gene Ontology (GO Annotations)
| GO ID | Source | Type | Description |
|---|---|---|---|
| GO:0030424 | IDA:WormBase | C | axon |
| GO:0044297 | IDA:WormBase | C | cell body |
| GO:0005829 | IDA:WormBase | C | cytosol |
| GO:0048471 | IDA:WormBase | C | perinuclear region of cytoplasm |
| GO:0005524 | IEA:UniProtKB-KW | F | ATP binding |
| GO:0003951 | IEA:InterPro | F | NAD+ kinase activity |
| GO:0017048 | IPI:WormBase | F | Rho GTPase binding |
| GO:0004143 | IDA:WormBase | F | diacylglycerol kinase activity |
| GO:0008270 | IEA:InterPro | F | zinc ion binding |
| GO:0007212 | IMP:WormBase | P | dopamine receptor signaling pathway |
| GO:0035556 | IEA:InterPro | P | intracellular signal transduction |
| GO:0046834 | IDA:WormBase | P | lipid phosphorylation |
| GO:0040013 | IMP:WormBase | P | negative regulation of locomotion |
| GO:0007205 | IEA:InterPro | P | protein kinase C-activating G-protein coupled receptor signaling pathway |
| GO:0040012 | IMP:WormBase | P | regulation of locomotion |
| GO:0046662 | IMP:WormBase | P | regulation of oviposition |
| GO:0032094 | IMP:WormBase | P | response to food |
| GO:0007210 | IMP:WormBase | P | serotonin receptor signaling pathway |
| GO:0007271 | IMP:WormBase | P | synaptic transmission, cholinergic |
Domain Information
InterPro Annotations
| Accession | Description |
|---|---|
| IPR016064 | ATP-NAD kinase-like domain |
| IPR000756 | Diacylglycerol kinase, accessory domain |
| IPR001206 | Diacylglycerol kinase, catalytic domain |
| IPR020454 | Diacylglycerol/phorbol-ester binding |
| IPR002219 | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain |
| IPR000159 | Ras-association |
| IPR029071 | Ubiquitin-related domain |
| IPR001965 | Zinc finger, PHD-type |
UniProt Annotations
Entry Information
Comments
| Comment Type | Description |
|---|---|
| Catalytic Activity | ATP + 1,2-diacyl-sn-glycerol = ADP + 1,2- diacyl-sn-glycerol 3-phosphate. |
| Similarity | Belongs to the eukaryotic diacylglycerol kinase family. |
| Similarity | Contains 1 DAGKc domain. |
| Similarity | Contains 2 Ras-associating domains. |
| Similarity | Contains 3 phorbol-ester/DAG-type zinc fingers. |
Identical and Related Proteins
Unique RefSeq proteins for LMP007810 (as displayed in Record Overview)
| Protein GI | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| 17551330 | RefSeq | NP_508191 | 950 | Protein DGK-1, isoform a |
| 17551332 | RefSeq | NP_508190 | 952 | Protein DGK-1, isoform b |
| 71982814 | RefSeq | NP_001024382 | 794 | Protein DGK-1, isoform c |
| 71982823 | RefSeq | NP_001024383 | 796 | Protein DGK-1, isoform d |
| 71982826 | RefSeq | NP_001024384 | 919 | Protein DGK-1, isoform e |
Identical Sequences to LMP007810 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:17551330 | EMBL | CCD63964.1 | 950 | Protein DGK-1, isoform a [Caenorhabditis elegans] |
| GI:17551332 | EMBL | CCD63965.1 | 952 | Protein DGK-1, isoform b [Caenorhabditis elegans] |
| GI:71982814 | EMBL | CCD63966.1 | 794 | Protein DGK-1, isoform c [Caenorhabditis elegans] |
| GI:71982823 | EMBL | CCD63967.1 | 796 | Protein DGK-1, isoform d [Caenorhabditis elegans] |
| GI:71982826 | EMBL | CCD63968.1 | 919 | Protein DGK-1, isoform e [Caenorhabditis elegans] |
| GI:17551332 | GenBank | ABZ32766.1 | 952 | Sequence 6704 from patent US 7314974 |
| GI:17551330 | GenBank | ABZ32767.1 | 950 | Sequence 6705 from patent US 7314974 |
Related Sequences to LMP007810 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:17551332 | EMBL | CAP27974.1 | 953 | Protein CBR-DGK-1 [Caenorhabditis briggsae] |
| GI:17551330 | EMBL | CAP27974.1 | 953 | Protein CBR-DGK-1 [Caenorhabditis briggsae] |
| GI:71982826 | EMBL | CCD63964.1 | 950 | Protein DGK-1, isoform a [Caenorhabditis elegans] |
| GI:17551332 | EMBL | CCD63964.1 | 950 | Protein DGK-1, isoform a [Caenorhabditis elegans] |
| GI:17551330 | EMBL | CCD63965.1 | 952 | Protein DGK-1, isoform b [Caenorhabditis elegans] |
| GI:71982826 | EMBL | CCD63965.1 | 952 | Protein DGK-1, isoform b [Caenorhabditis elegans] |
| GI:71982823 | EMBL | CCD63965.1 | 952 | Protein DGK-1, isoform b [Caenorhabditis elegans] |
| GI:71982814 | EMBL | CCD63965.1 | 952 | Protein DGK-1, isoform b [Caenorhabditis elegans] |
| GI:71982823 | EMBL | CCD63966.1 | 794 | Protein DGK-1, isoform c [Caenorhabditis elegans] |
| GI:71982814 | EMBL | CCD63967.1 | 796 | Protein DGK-1, isoform d [Caenorhabditis elegans] |
| GI:17551330 | EMBL | CCD63968.1 | 919 | Protein DGK-1, isoform e [Caenorhabditis elegans] |
| GI:71982826 | GenBank | ABZ32766.1 | 952 | Sequence 6704 from patent US 7314974 |
| GI:17551330 | GenBank | ABZ32766.1 | 952 | Sequence 6704 from patent US 7314974 |
| GI:71982814 | GenBank | ABZ32766.1 | 952 | Sequence 6704 from patent US 7314974 |
| GI:71982823 | GenBank | ABZ32766.1 | 952 | Sequence 6704 from patent US 7314974 |
| GI:71982826 | GenBank | ABZ32767.1 | 950 | Sequence 6705 from patent US 7314974 |
| GI:71982814 | GenBank | ABZ32767.1 | 950 | Sequence 6705 from patent US 7314974 |
| GI:71982823 | GenBank | ABZ32767.1 | 950 | Sequence 6705 from patent US 7314974 |
| GI:17551332 | GenBank | ABZ32767.1 | 950 | Sequence 6705 from patent US 7314974 |
| GI:17551332 | GenBank | EGT54820.1 | 940 | CBN-DGK-1 protein [Caenorhabditis brenneri] |
| GI:17551332 | RefSeq | NP_508191.1 | 950 | Protein DGK-1, isoform a [Caenorhabditis elegans] |
| GI:71982826 | RefSeq | NP_508191.1 | 950 | Protein DGK-1, isoform a [Caenorhabditis elegans] |
| GI:71982823 | RefSeq | NP_508190.1 | 952 | Protein DGK-1, isoform b [Caenorhabditis elegans] |
| GI:71982814 | RefSeq | NP_508190.1 | 952 | Protein DGK-1, isoform b [Caenorhabditis elegans] |
| GI:17551330 | RefSeq | NP_508190.1 | 952 | Protein DGK-1, isoform b [Caenorhabditis elegans] |
| GI:71982826 | RefSeq | NP_508190.1 | 952 | Protein DGK-1, isoform b [Caenorhabditis elegans] |
| GI:71982823 | RefSeq | NP_001024382.1 | 794 | Protein DGK-1, isoform c [Caenorhabditis elegans] |
| GI:71982814 | RefSeq | NP_001024383.1 | 796 | Protein DGK-1, isoform d [Caenorhabditis elegans] |
| GI:17551330 | RefSeq | XP_002643213.1 | 953 | C. briggsae CBR-DGK-1 protein [Caenorhabditis briggsae] |
| GI:17551332 | RefSeq | XP_002643213.1 | 953 | C. briggsae CBR-DGK-1 protein [Caenorhabditis briggsae] |