Gene/Proteome Database (LMPD)

LMPD ID
LMP007822
Gene ID
175192
Species
Caenorhabditis elegans (C. elegans)
Gene Name
Protein ADS-1
Gene Symbol
ads-1
Synonyms
CELE_Y50D7A.7
Alternate Names
Protein ADS-1
Chromosome
III
EC Number
2.5.1.26

Proteins

Protein ADS-1
Refseq ID NP_497185
Protein GI 17556096
UniProt ID O45218
mRNA ID NM_064784
Length 597
RefSeq Status REVIEWED
MSASYQTIEHDVPQSYRDKILKWNGWGYSDSQFAINKDGHVTFTGDKYEISGKVMPHFRPWFENYLGIDLGFVSPAQKLSDVIIDAPVENEDIIEFLQENKISFSNEARIRLMRGHGHTVHDMINLREGKIPRLPDIVVWPKSEHEIVKIIEGAMSHNCAIIPIGGGTSVTNALDTPETEKRAVISMDMALLDKILWIDRENLTCRAQAGIVGQSLERQLNKKGFTCGHEPDSIEFSTLGGWVSTRASGMKKNKYGNIEDLVVHLNFVCPKGIIQKQCQVPRMSSGPDIHQIILGSEGTLGVVSEVTIKIFPIPEVKRFGSFVFPNFESGVNFFREVAIQRCQPASLRLMDNDQFVMGQALKVASDSWWADLKSSVSKMYITSWKGFKVDEICAATCVYEGNREEVDQHEERLNKLAEQFHGVVGGAENGQYGYRLTFAIAYLRDLGMNHGVLGESFETSVPWDKVLSLCRNVKELMKREAKAQGVTHPVLANCRVTQVYDAGACVYFYFGFNARGLKNGLEVYDRIETAARDEIIACGGSISHHHGVGKIRKQWMLTTNGAVGIALLKAIKSELDPANIFASANLIDIIGSPHCKL

Gene Information

Entrez Gene ID
175192
Gene Name
Protein ADS-1
Gene Symbol
ads-1
Species
Caenorhabditis elegans

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005777 IEA:UniProtKB-KW C peroxisome
GO:0071949 ISS:UniProtKB F FAD binding
GO:0008762 IEA:InterPro F UDP-N-acetylmuramate dehydrogenase activity
GO:0008609 ISS:UniProtKB F alkylglycerone-phosphate synthase activity
GO:0008611 ISS:UniProtKB P ether lipid biosynthetic process

KEGG Pathway Links

KEGG Pathway ID Description
cel00565 Ether lipid metabolism
cel04146 Peroxisome

REACTOME Pathway Links

REACTOME Pathway ID Description
5652681 Plasmalogen biosynthesis

Domain Information

InterPro Annotations

Accession Description
IPR025650 Alkyldihydroxyacetonephosphate synthase
IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2
IPR006094 FAD linked oxidase, N-terminal
IPR016166 FAD-binding, type 2
IPR016167 FAD-binding, type 2, subdomain 1
IPR004113 FAD-linked oxidase, C-terminal
IPR016164 FAD-linked oxidase-like, C-terminal

UniProt Annotations

Entry Information

Gene Name
Protein ADS-1
Protein Entry
ADAS_CAEEL
UniProt ID
O45218
Species
C. elegans

Comments

Comment Type Description
Catalytic Activity 1-acyl-glycerone 3-phosphate + a long-chain alcohol = an alkyl-glycerone 3-phosphate + a long-chain acid anion.
Cofactor Name=FAD; Xref=ChEBI:CHEBI:57692; Evidence={ECO:0000250};
Function Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids. {ECO:0000250}.
Pathway Glycerolipid metabolism; ether lipid biosynthesis.
Similarity Belongs to the FAD-binding oxidoreductase/transferase type 4 family. {ECO:0000305}.
Similarity Contains 1 FAD-binding PCMH-type domain. {ECO:0000255|PROSITE-ProRule:PRU00718}.
Subcellular Location Peroxisome.
Subunit Homodimer. {ECO:0000250}.

Identical and Related Proteins

Unique RefSeq proteins for LMP007822 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
17556096 RefSeq NP_497185 597 Protein ADS-1

Identical Sequences to LMP007822 proteins

Reference Database Accession Length Protein Name
GI:17556096 EMBL CAA05690.1 597 alkyl-dihydroxyacetonephosphate synthase [Caenorhabditis elegans]
GI:17556096 EMBL CCD73794.1 597 Protein ADS-1 [Caenorhabditis elegans]
GI:17556096 SwissProt O45218.1 597 RecName: Full=Alkyldihydroxyacetonephosphate synthase; Short=Alkyl-DHAP synthase; AltName: Full=Alkylglycerone-phosphate synthase [Caenorhabditis elegans]

Related Sequences to LMP007822 proteins

Reference Database Accession Length Protein Name
GI:17556096 EMBL CAP33892.1 597 Protein CBR-ADS-1 [Caenorhabditis briggsae]
GI:17556096 GenBank EFP08408.1 597 CRE-ADS-1 protein [Caenorhabditis remanei]
GI:17556096 GenBank EGT47786.1 597 CBN-ADS-1 protein [Caenorhabditis brenneri]
GI:17556096 GenBank EYC27684.1 594 hypothetical protein Y032_0008g128 [Ancylostoma ceylanicum]
GI:17556096 RefSeq XP_002640829.1 597 C. briggsae CBR-ADS-1 protein [Caenorhabditis briggsae]
GI:17556096 RefSeq XP_003100881.1 597 CRE-ADS-1 protein [Caenorhabditis remanei]