Gene/Proteome Database (LMPD)

LMPD ID
LMP007846
Gene ID
173118
Species
Caenorhabditis elegans (C. elegans)
Gene Name
Protein T27F6.6
Gene Symbol
T27F6.6
Synonyms
CELE_T27F6.6
Alternate Names
Protein T27F6.6
Chromosome
I
EC Number
3.1.4.12

Proteins

Protein T27F6.6
Refseq ID NP_493169
Protein GI 71991697
UniProt ID O45870
mRNA ID NM_060768
Length 434
RefSeq Status REVIEWED
MEPSSEQESQESQKVDMEPVFRRESFAALRRNNVAARQLRVVTLNAWCLPQPWPIGSTDRVHRLNKIGQYMIDELYDIVGLQELWSYYDFVRLSEQVSSVYPYFHYFHSGFTGSGVCVFSRHPIVSTLTNRYSLNGFAHHIHRGDWFGGKVVGLTEIEIDGDLRVNFYTTHLHAEYDRENDLYLPHRTAQAFELAQFVRHTARGADVVIVTGDLNMEPCDLGFRLILSHAKLFDAWRMSHEVENEDSEGELLKFRGIAKGGTCDRPDNCYTKRALKNVDDSKRIDYMLFKSGRCNVKLEECEITLNQIPGEDLNYSDHVGLRARFTIDDRFRHEKSVNTWEPNRPLLIEAIGLVAGGERRARTDRIFFFILAVICLILILGSLFFEVFPMGFAVLRFALTVVGVFFVWQGLIGLTLERKALKAAKQAIQQILNN

Gene Information

Entrez Gene ID
173118
Gene Name
Protein T27F6.6
Gene Symbol
T27F6.6
Species
Caenorhabditis elegans

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0046872 IEA:UniProtKB-KW F metal ion binding
GO:0004767 IEA:UniProtKB-EC F sphingomyelin phosphodiesterase activity
GO:0006665 IEA:UniProtKB-UniPathway P sphingolipid metabolic process

KEGG Pathway Links

KEGG Pathway ID Description
cel01100 Metabolic pathways
cel00600 Sphingolipid metabolism

REACTOME Pathway Links

REACTOME Pathway ID Description
5653416 Glycosphingolipid metabolism
5653217 Sphingolipid metabolism

Domain Information

InterPro Annotations

Accession Description
IPR005135 Endonuclease/exonuclease/phosphatase

UniProt Annotations

Entry Information

Gene Name
Protein T27F6.6
Protein Entry
NSMA_CAEEL
UniProt ID
O45870
Species
C. elegans

Comments

Comment Type Description
Catalytic Activity Sphingomyelin + H(2)O = N-acylsphingosine + phosphocholine.
Pathway Lipid metabolism; sphingolipid metabolism.
Similarity Belongs to the neutral sphingomyelinase family. {ECO:0000305}.
Subcellular Location Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.

Identical and Related Proteins

Unique RefSeq proteins for LMP007846 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
71991697 RefSeq NP_493169 434 Protein T27F6.6

Identical Sequences to LMP007846 proteins

Reference Database Accession Length Protein Name
GI:71991697 EMBL CAB04885.2 434 Protein T27F6.6 [Caenorhabditis elegans]
GI:71991697 SwissProt O45870.2 434 RecName: Full=Putative neutral sphingomyelinase [Caenorhabditis elegans]

Related Sequences to LMP007846 proteins

Reference Database Accession Length Protein Name
GI:71991697 EMBL CDJ89479.1 438 Endonuclease exonuclease phosphatase domain containing protein [Haemonchus contortus]
GI:71991697 GenBank EFO91019.1 445 hypothetical protein CRE_25821 [Caenorhabditis remanei]
GI:71991697 GenBank EGT31359.1 436 hypothetical protein CAEBREN_30748 [Caenorhabditis brenneri]
GI:71991697 GenBank EGT52621.1 436 hypothetical protein CAEBREN_28256 [Caenorhabditis brenneri]
GI:71991697 GenBank ETN75632.1 524 endonuclease/exonuclease/phosphatase family protein [Necator americanus]
GI:71991697 RefSeq XP_003094670.1 445 hypothetical protein CRE_25821 [Caenorhabditis remanei]