Gene/Proteome Database (LMPD)

LMPD ID
LMP007936
Gene ID
173305
Species
Caenorhabditis elegans (C. elegans)
Gene Name
Protein HPO-13
Gene Symbol
hpo-13
Synonyms
CELE_Y105E8A.10
Chromosome
I

Proteins

Protein HPO-13, isoform a
Refseq ID NP_001021680
Protein GI 71992715
UniProt ID Q8WQB2
mRNA ID NM_001026509
Length 959
RefSeq Status REVIEWED
MFCSFFHEKKKNILRLNIRCQRLREHDNTAKIELFKSMRRRRSSTKASRKTTMGGAAELEDEWIPSETMSGAGWKARGDRKPKDKRVPFNRPTPYQIYEALPFVRRYFMYWMKHTFDKEKLFINTFQPLKHKPYYGVPCGGIGCGAIGRDFRGGFCKFSLRPGLVEHKVDVVAADQFILSVRENDRCIYQKVLSAADVQRPSGQLSTWDFKFPKKNVHYRGLFPRSWTTFRVPELELTVVIRQVSPVLPHNYEDTTYPVCLFLIDVENGGSASREYEISVAFTFRNGTGNRRWEREAECSGVKFETEEEGLKPTTTAQEKISGVSLYHTISSMPCTYGLATTHREHTTTTVCERFDPSRNGAALWNHLKQTGDVPSCEEECLINAREMAVAVCNRFTLPPNSTKTHDYALSWDMPKVHFGSVARSYHRRYTRFFEASEAGSAADSLCVRALRLKDKWESEIEAWQSPILNHKKLPDWYKSAIFNELYFITDGGTVWFEFDENWAEHETHLSHYTKDKMKEIGRFGYLESWEYRMVNTYDVHFYASFALAELWPELEITIQSEFTDQVYHSIEKPTRFHMEGDWANVKTASRVPHDLGNPADEPWIATNAYVMHDTGKWKDLNMKYVLTSWRDYVVLSNEHEDFLFHTWPAVRMIMLEALENWDQDGDGMIENFGKADQTYDAWQMEGVSAYCGSLWLASLRVAIEMAGLMKDDETQQLFRNTLEKAKKVFIDTLWTGTYFRFCERSRSRETVMADQLCGYWFLQSVSPELADELLPNHMVRSALDTIYRLNVCKFGNGRMGAVNGMKPSGVVDREYIQADEMWTGVTYAVASLLIQQGEVEKAFHTASGSYLTCFEETGLQYQTPEALYESKFYRAIGYMRPLSIWAMQWSLKKHCGMNTSEEKLPNLVKNEKVVPESEAAIQVQKQRILGDTSEDGSSLGYVSDYHDERSIPKIATLR
Protein HPO-13, isoform b
Refseq ID NP_001021681
Protein GI 71992723
UniProt ID Q6EUT4
mRNA ID NM_001026510
Length 930
RefSeq Status REVIEWED
MRIGCCTSMRRRRSSTKASRKTTMGGAAELEDEWIPSETMSGAGWKARGDRKPKDKRVPFNRPTPYQIYEALPFVRRYFMYWMKHTFDKEKLFINTFQPLKHKPYYGVPCGGIGCGAIGRDFRGGFCKFSLRPGLVEHKVDVVAADQFILSVRENDRCIYQKVLSAADVQRPSGQLSTWDFKFPKKNVHYRGLFPRSWTTFRVPELELTVVIRQVSPVLPHNYEDTTYPVCLFLIDVENGGSASREYEISVAFTFRNGTGNRRWEREAECSGVKFETEEEGLKPTTTAQEKISGVSLYHTISSMPCTYGLATTHREHTTTTVCERFDPSRNGAALWNHLKQTGDVPSCEEECLINAREMAVAVCNRFTLPPNSTKTHDYALSWDMPKVHFGSVARSYHRRYTRFFEASEAGSAADSLCVRALRLKDKWESEIEAWQSPILNHKKLPDWYKSAIFNELYFITDGGTVWFEFDENWAEHETHLSHYTKDKMKEIGRFGYLESWEYRMVNTYDVHFYASFALAELWPELEITIQSEFTDQVYHSIEKPTRFHMEGDWANVKTASRVPHDLGNPADEPWIATNAYVMHDTGKWKDLNMKYVLTSWRDYVVLSNEHEDFLFHTWPAVRMIMLEALENWDQDGDGMIENFGKADQTYDAWQMEGVSAYCGSLWLASLRVAIEMAGLMKDDETQQLFRNTLEKAKKVFIDTLWTGTYFRFCERSRSRETVMADQLCGYWFLQSVSPELADELLPNHMVRSALDTIYRLNVCKFGNGRMGAVNGMKPSGVVDREYIQADEMWTGVTYAVASLLIQQGEVEKAFHTASGSYLTCFEETGLQYQTPEALYESKFYRAIGYMRPLSIWAMQWSLKKHCGMNTSEEKLPNLVKNEKVVPESEAAIQVQKQRILGDTSEDGSSLGYVSDYHDERSIPKIATLR
Protein HPO-13, isoform c
Refseq ID NP_001021682
Protein GI 71992731
UniProt ID Q6EUT3
mRNA ID NM_001026511
Length 922
RefSeq Status REVIEWED
MRRRRSSTKASRKTTMGGAAELEDEWIPSETMSGAGWKARGDRKPKDKRVPFNRPTPYQIYEALPFVRRYFMYWMKHTFDKEKLFINTFQPLKHKPYYGVPCGGIGCGAIGRDFRGGFCKFSLRPGLVEHKVDVVAADQFILSVRENDRCIYQKVLSAADVQRPSGQLSTWDFKFPKKNVHYRGLFPRSWTTFRVPELELTVVIRQVSPVLPHNYEDTTYPVCLFLIDVENGGSASREYEISVAFTFRNGTGNRRWEREAECSGVKFETEEEGLKPTTTAQEKISGVSLYHTISSMPCTYGLATTHREHTTTTVCERFDPSRNGAALWNHLKQTGDVPSCEEECLINAREMAVAVCNRFTLPPNSTKTHDYALSWDMPKVHFGSVARSYHRRYTRFFEASEAGSAADSLCVRALRLKDKWESEIEAWQSPILNHKKLPDWYKSAIFNELYFITDGGTVWFEFDENWAEHETHLSHYTKDKMKEIGRFGYLESWEYRMVNTYDVHFYASFALAELWPELEITIQSEFTDQVYHSIEKPTRFHMEGDWANVKTASRVPHDLGNPADEPWIATNAYVMHDTGKWKDLNMKYVLTSWRDYVVLSNEHEDFLFHTWPAVRMIMLEALENWDQDGDGMIENFGKADQTYDAWQMEGVSAYCGSLWLASLRVAIEMAGLMKDDETQQLFRNTLEKAKKVFIDTLWTGTYFRFCERSRSRETVMADQLCGYWFLQSVSPELADELLPNHMVRSALDTIYRLNVCKFGNGRMGAVNGMKPSGVVDREYIQADEMWTGVTYAVASLLIQQGEVEKAFHTASGSYLTCFEETGLQYQTPEALYESKFYRAIGYMRPLSIWAMQWSLKKHCGMNTSEEKLPNLVKNEKVVPESEAAIQVQKQRILGDTSEDGSSLGYVSDYHDERSIPKIATLR

Gene Information

Entrez Gene ID
173305
Gene Name
Protein HPO-13
Gene Symbol
hpo-13
Species
Caenorhabditis elegans

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0016021 IEA:InterPro C integral component of membrane
GO:0005886 IEA:UniProtKB-SubCell C plasma membrane
GO:0004348 IEA:UniProtKB-EC F glucosylceramidase activity
GO:0006680 IEA:InterPro P glucosylceramide catabolic process

Domain Information

InterPro Annotations

Accession Description
IPR014551 Beta-glucosidase, GBA2 type
IPR024462 Beta-glucosidase, GBA2 type, N-terminal
IPR006775 Glucosylceramidase
IPR008928 Six-hairpin glycosidase-like

UniProt Annotations

Entry Information

Gene Name
Protein HPO-13
Protein Entry
Q8WQB2_CAEEL
UniProt ID
Q8WQB2
Species
C. elegans

Comments

Comment Type Description
Catalytic Activity D-glucosyl-N-acylsphingosine + H(2)O = D- glucose + N-acylsphingosine.
Function Non-lysosomal glucosylceramidase that catalyzes the conversion of glucosylceramide to free glucose and ceramide.
Similarity Belongs to the non-lysosomal glucosylceramidase family.
Subcellular Location Cell membrane .

Identical and Related Proteins

Unique RefSeq proteins for LMP007936 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
71992715 RefSeq NP_001021680 959 Protein HPO-13, isoform a
71992723 RefSeq NP_001021681 930 Protein HPO-13, isoform b
71992731 RefSeq NP_001021682 922 Protein HPO-13, isoform c

Identical Sequences to LMP007936 proteins

Reference Database Accession Length Protein Name
GI:71992731 EMBL CAC48128.1 922 Protein HPO-13, isoform c [Caenorhabditis elegans]
GI:71992715 EMBL CAD21661.1 959 Protein HPO-13, isoform a [Caenorhabditis elegans]
GI:71992723 EMBL CAH04764.1 930 Protein HPO-13, isoform b [Caenorhabditis elegans]

Related Sequences to LMP007936 proteins

Reference Database Accession Length Protein Name
GI:71992723 EMBL CAC48128.1 922 Protein HPO-13, isoform c [Caenorhabditis elegans]
GI:71992715 EMBL CAC48128.1 922 Protein HPO-13, isoform c [Caenorhabditis elegans]
GI:71992723 EMBL CAD21661.1 959 Protein HPO-13, isoform a [Caenorhabditis elegans]
GI:71992731 EMBL CAD21661.1 959 Protein HPO-13, isoform a [Caenorhabditis elegans]
GI:71992731 EMBL CAH04764.1 930 Protein HPO-13, isoform b [Caenorhabditis elegans]
GI:71992715 EMBL CAH04764.1 930 Protein HPO-13, isoform b [Caenorhabditis elegans]
GI:71992723 GenBank EFP00966.1 933 hypothetical protein CRE_20734 [Caenorhabditis remanei]
GI:71992715 GenBank EFP00966.1 933 hypothetical protein CRE_20734 [Caenorhabditis remanei]
GI:71992731 GenBank EFP00966.1 933 hypothetical protein CRE_20734 [Caenorhabditis remanei]
GI:71992723 RefSeq NP_001021680.1 959 Protein HPO-13, isoform a [Caenorhabditis elegans]
GI:71992731 RefSeq NP_001021680.1 959 Protein HPO-13, isoform a [Caenorhabditis elegans]
GI:71992731 RefSeq NP_001021681.1 930 Protein HPO-13, isoform b [Caenorhabditis elegans]
GI:71992715 RefSeq NP_001021681.1 930 Protein HPO-13, isoform b [Caenorhabditis elegans]
GI:71992723 RefSeq NP_001021682.1 922 Protein HPO-13, isoform c [Caenorhabditis elegans]
GI:71992715 RefSeq NP_001021682.1 922 Protein HPO-13, isoform c [Caenorhabditis elegans]
GI:71992731 RefSeq XP_003105068.1 933 hypothetical protein CRE_20734 [Caenorhabditis remanei]
GI:71992723 RefSeq XP_003105068.1 933 hypothetical protein CRE_20734 [Caenorhabditis remanei]
GI:71992715 RefSeq XP_003105068.1 933 hypothetical protein CRE_20734 [Caenorhabditis remanei]