Gene/Proteome Database (LMPD)

LMPD ID
LMP007938
Gene ID
173574
Species
Caenorhabditis elegans (C. elegans)
Gene Name
Protein GBA-1
Gene Symbol
gba-1
Synonyms
CELE_C33C12.3
Alternate Names
Protein GBA-1
Chromosome
II
EC Number
3.2.1.45

Proteins

Protein GBA-1, isoform a
Refseq ID NP_001040750
Protein GI 115532470
UniProt ID O16580
mRNA ID NM_001047285
Length 523
RefSeq Status REVIEWED
MKSRFLLKIFIFLAVFGVDSVRAADCTEKTFKTGTVCVCSLDSCDEIPPLDITMGQAALYTTSHTGARLHRDVIYATDTEPFGTLHMTIDSSKKYQTIQGFGSTFSDASGANLKSLPDKLSDLIMKQYFSDTGLNLQFGRVPIASTDFSGRVYSYNDVANDYSMQNFNLTKEDFQWKIPYIKNAQKYNPNLKLFAAPWAAPGWLKTTKEMTGPGALNGKAGDNYHQAYAKYFVRFLEEYGKSGISFWGLSTQNQPTLGSDKKNKIQSTLFTAETQRDFIKTDLGPALAASSSGKDVKLLILDDNRGNLPKWADTVLNDMDAAKYVGGIGVHAYQDGETDNHLDETHKKHPNFFILGTEASEGYGSKDTHVDYGNWDRAADTASDILDNMNNWMTGWTERNLILDALGGPSWVSDYTDAPVIAFPAMAQFYKQPMFYAIAHFSHFIKPGAVRIDHSLNVIELEVETTAFLNPDGSKVIVMLNKGSLVSTEHTVVVQDAADSRNHYHFTLPHRAITTLYIQTSQF
Protein GBA-1, isoform b
Refseq ID NP_001040751
Protein GI 115532472
UniProt ID O16580
mRNA ID NM_001047286
Length 470
RefSeq Status REVIEWED
MGQAALYTTSHTGARLHRDVIYATDTEPFGTLHMTIDSSKKYQTIQGFGSTFSDASGANLKSLPDKLSDLIMKQYFSDTGLNLQFGRVPIASTDFSGRVYSYNDVANDYSMQNFNLTKEDFQWKIPYIKNAQKYNPNLKLFAAPWAAPGWLKTTKEMTGPGALNGKAGDNYHQAYAKYFVRFLEEYGKSGISFWGLSTQNQPTLGSDKKNKIQSTLFTAETQRDFIKTDLGPALAASSSGKDVKLLILDDNRGNLPKWADTVLNDMDAAKYVGGIGVHAYQDGETDNHLDETHKKHPNFFILGTEASEGYGSKDTHVDYGNWDRAADTASDILDNMNNWMTGWTERNLILDALGGPSWVSDYTDAPVIAFPAMAQFYKQPMFYAIAHFSHFIKPGAVRIDHSLNVIELEVETTAFLNPDGSKVIVMLNKGSLVSTEHTVVVQDAADSRNHYHFTLPHRAITTLYIQTSQF

Gene Information

Entrez Gene ID
173574
Gene Name
Protein GBA-1
Gene Symbol
gba-1
Species
Caenorhabditis elegans

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0004348 IEA:UniProtKB-EC F glucosylceramidase activity
GO:0005975 IEA:InterPro P carbohydrate metabolic process
GO:0006665 IEA:UniProtKB-UniPathway P sphingolipid metabolic process

KEGG Pathway Links

KEGG Pathway ID Description
cel04142 Lysosome
ko04142 Lysosome
cel01100 Metabolic pathways
cel00600 Sphingolipid metabolism

Domain Information

InterPro Annotations

Accession Description
IPR017853 Glycoside hydrolase superfamily
IPR013781 Glycoside hydrolase, catalytic domain
IPR001139 Glycoside hydrolase, family 30
IPR013780 Glycosyl hydrolase, family 13, all-beta

UniProt Annotations

Entry Information

Gene Name
Protein GBA-1
Protein Entry
GLCM1_CAEEL
UniProt ID
O16580
Species
C. elegans

Comments

Comment Type Description
Alternative Products Event=Alternative splicing; Named isoforms=2; Name=a; IsoId=O16580-1; Sequence=Displayed; Name=b; IsoId=O16580-2; Sequence=VSP_045724;
Catalytic Activity D-glucosyl-N-acylsphingosine + H(2)O = D- glucose + N-acylsphingosine.
Pathway Lipid metabolism; sphingolipid metabolism.
Similarity Belongs to the glycosyl hydrolase 30 family. {ECO:0000305}.

Identical and Related Proteins

Unique RefSeq proteins for LMP007938 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
115532470 RefSeq NP_001040750 523 Protein GBA-1, isoform a
115532472 RefSeq NP_001040751 470 Protein GBA-1, isoform b

Identical Sequences to LMP007938 proteins

Reference Database Accession Length Protein Name
GI:115532470 EMBL CCD66449.1 523 Protein GBA-1, isoform a [Caenorhabditis elegans]
GI:115532472 EMBL CCD66450.1 470 Protein GBA-1, isoform b [Caenorhabditis elegans]
GI:115532470 SwissProt O16580.2 523 RecName: Full=Putative glucosylceramidase 1; Flags: Precursor [Caenorhabditis elegans]

Related Sequences to LMP007938 proteins

Reference Database Accession Length Protein Name
GI:115532472 EMBL CCD66449.1 523 Protein GBA-1, isoform a [Caenorhabditis elegans]
GI:115532470 EMBL CCD66450.1 470 Protein GBA-1, isoform b [Caenorhabditis elegans]
GI:115532470 GenBank ABZ31400.1 566 Sequence 5338 from patent US 7314974
GI:115532472 GenBank ABZ31400.1 566 Sequence 5338 from patent US 7314974
GI:115532472 GenBank EGT57795.1 525 hypothetical protein CAEBREN_17884 [Caenorhabditis brenneri]
GI:115532470 GenBank EGT57795.1 525 hypothetical protein CAEBREN_17884 [Caenorhabditis brenneri]
GI:115532472 RefSeq NP_001040750.1 523 Protein GBA-1, isoform a [Caenorhabditis elegans]
GI:115532470 RefSeq NP_001040751.1 470 Protein GBA-1, isoform b [Caenorhabditis elegans]
GI:115532470 RefSeq XP_002632088.1 524 Hypothetical protein CBG17056 [Caenorhabditis briggsae]
GI:115532472 RefSeq XP_003098444.1 541 hypothetical protein CRE_06915 [Caenorhabditis remanei]
GI:115532470 RefSeq XP_003098444.1 541 hypothetical protein CRE_06915 [Caenorhabditis remanei]
GI:115532472 SwissProt O16580.2 523 RecName: Full=Putative glucosylceramidase 1; Flags: Precursor [Caenorhabditis elegans]