Gene/Proteome Database (LMPD)

LMPD ID
LMP007953
Gene ID
174586
Species
Caenorhabditis elegans (C. elegans)
Gene Name
Protein PLC-3
Gene Symbol
plc-3
Synonyms
CELE_T01E8.3
Chromosome
II

Proteins

Protein PLC-3
Refseq ID NP_496205
Protein GI 212645511
UniProt ID Q22070
mRNA ID NM_063804
Length 1350
RefSeq Status REVIEWED
MQHGSLGPSSSSRKTTVTSTAGSVHLHHRSSNGFSTASRAQLNRHNEMDFGKMFAAMEKGHKVCKIAVLKKWDPAYKQLTLDRYSRQIFLTKLELSAVRNKPTILDIRQIREVQTLNYKLNTIKVDDKWKKDREIVNFDSKAILIISYGMGFALSYWILLFESEDACKLWSQGLHNLMMDTRDRDSSPHPLRIERFLHKHFLSLMSPANDAVARKHMKPFVQTSLQFKVQSDQLQQVTEDQMNSDQFSFASRQLIHVPELFSSRFADLAEKHERKGLVVTFQNFLRFLDGKQFDELASNRTRALEFLNRYFQEDQAYFGDRNEPSMTVFEFCDFLFSRENSLWDPTNEKVTHDMSRPLSHYWIASSHNTYLTGDQLRSESSLDCYAQALLMGCRCIELDCWDGQKKPGSAEFIDIVIYHGYTMTSKILLRDVLHVIRHYAFVTSEYPVILSIEDNCSVPAQRLLAQELKDILGDYLLTQPANREEKQLPSPAALKKKIIVKHKKLPIESEDLAAVVKTDEFQDTEIISRECVKKGILMVKNNNSHEWTSHVFILFPDRLCYLIQTADPENPNDDTVSVSGDEEREEETPSGFGVKPEEMHVTEEWFHGRCERDEAKKRILEHKEKGNGLFMIRDSNLFIGDFSLSILHDGKVHHVRIRSKIIDKEKKYYFMDNKVCDTLYELVSYYTRHYLTTAHFKMVLTIPCPQPQPHLNQPWFSATADKEKAEELLSLVPEDGAFLIRTSSTDSSVYVLSLKVDGEFWHYRLKRDGRIFVVNQKVFENLNQIVEFYANREFVRGISLRFPVNEKDISHLTAELAEARTPGCYMDLKDLDKEVQARALRPYRGTADDELSFPANVIITVLRKEEGLWRGRYGSLTGWFPSAHVQEILPEKVSTSETSNYNTIELAGTLIERIHDADRPNVIRISQSNQHWMNKQYYLLAASSSEEADGWQNNLFELTRSVNTKMSILRTKEKEKRIAAELSNLVVYCQAVPFDPAHIYNDAFYEMCSFVEGKLDKLVEKGLLPFNSRKLSRVYPNGSRITSNNYSPVPMWNAGCHMVALNYQTGDKPMQLNQGKFLANGRCGYLLKPDYMLTDDFDPTNTEKFATAYPIRLNVQVIGGRHLSRKDKNKGICSPFVEIEIIGMPCDTKVFQTKTIASNGLNPIWNQTFTFEIQCPEVALIRFHVEDGDFVGPKTDPFIGQAVFPVDSIRCGFRSVPLKNQYSEELELSSLLVDVQMCSREGTQLIRSSSHFLQASRLAPVFAHRKITNGDSIPREMAPRLRTSATDRSLDSPTNSESRATLLSGQRGSQDSMDSAAETSSIASGTISSRDGKKKQNWLKKFSFGKSSKS

Gene Information

Entrez Gene ID
174586
Gene Name
Protein PLC-3
Gene Symbol
plc-3
Species
Caenorhabditis elegans

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0004435 IEA:UniProtKB-EC F phosphatidylinositol phospholipase C activity
GO:0004871 IEA:UniProtKB-KW F signal transducer activity
GO:0035556 IEA:InterPro P intracellular signal transduction
GO:0009395 IEA:InterPro P phospholipid catabolic process

Domain Information

InterPro Annotations

Accession Description
IPR000008 C2 domain
IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain
IPR016279 Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase gamma
IPR001192 Phosphoinositide phospholipase C family
IPR000909 Phospholipase C, phosphatidylinositol-specific , X domain
IPR001711 Phospholipase C, phosphatidylinositol-specific, Y domain
IPR015359 Phospholipase C, phosphoinositol-specific, EF-hand-like
IPR001849 Pleckstrin homology domain
IPR011993 Pleckstrin homology-like domain
IPR000980 SH2 domain
IPR001452 SH3_domain

UniProt Annotations

Entry Information

Gene Name
Protein PLC-3
Protein Entry
Q22070_CAEEL
UniProt ID
Q22070
Species
C. elegans

Comments

Comment Type Description
Catalytic Activity 1-phosphatidyl-1D-myo-inositol 4,5- bisphosphate + H(2)O = 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol.
Similarity Contains 1 C2 domain.
Similarity Contains 1 PH domain.
Similarity Contains 1 PI-PLC X-box domain.
Similarity Contains 1 PI-PLC Y-box domain.
Similarity Contains C2 domain.
Similarity Contains Cdomain.
Similarity Contains PH domain.
Similarity Contains PI-PLC X-box domain.
Similarity Contains PI-PLC Y-box domain.

Identical and Related Proteins

Unique RefSeq proteins for LMP007953 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
212645511 RefSeq NP_496205 1350 Protein PLC-3

Identical Sequences to LMP007953 proteins

Reference Database Accession Length Protein Name
GI:212645511 EMBL CAA88745.2 1350 Protein PLC-3 [Caenorhabditis elegans]

Related Sequences to LMP007953 proteins

Reference Database Accession Length Protein Name
GI:212645511 EMBL CBF74594.1 1299 unnamed protein product [Caenorhabditis elegans]
GI:212645511 EMBL CBF62902.1 1299 unnamed protein product [Caenorhabditis elegans]
GI:212645511 EMBL CBU87778.1 1299 unnamed protein product [Caenorhabditis elegans]
GI:212645511 EMBL CBU96725.1 1299 unnamed protein product [Caenorhabditis elegans]
GI:212645511 GenBank ABZ31606.1 1299 Sequence 5544 from patent US 7314974
GI:212645511 GenBank AGX54713.1 1299 Sequence 9782 from patent US 8541208