Gene/Proteome Database (LMPD)

LMPD ID
LMP008013
Gene ID
179185
Species
Caenorhabditis elegans (C. elegans)
Gene Name
Protein ZC513.5
Gene Symbol
CELE_ZC513.5
Synonyms
CELE_ZC513.5
Alternate Names
Protein ZC513.5
Chromosome
V
EC Number
2.4.1.260

Proteins

Protein ZC513.5
Refseq ID NP_505071
Protein GI 17566740
UniProt ID Q23361
mRNA ID NM_072670
Length 492
RefSeq Status REVIEWED
MEGTEWIVIIVTIIHIILAPGTKVEESFNVQATHDLMFHLPTNLSNYDHSQFPGVVPRTFIGPISLAILSSPMSFIFRFWAIPKMWQLLLIRATLGLMNAMAFLYFARSVNRKFGRETAMYLRLIMCTQFHYIFYMSRPLPNTFALILVMIVFERLLEGRYESAVRYATASVILFRCELVLLYGPIFLGYMISGRLKVFGFDGAIAIGVRIAAMCLAVSIPIDSYFWGRPLWPEGEVMFFNVVENRSHEYGTQPFLWYFYSALPRCLLTTTLLVPLGLLVDRRLPQIVLPSVIFIFLYSFLPHKELRFIIYVLPIFCLSAAVFCARMLINRHKSFFRMILFFGVILHLLANVLCTGMFLLVASKNYPGFDALNYLQFQNRFDAKKPVTVYIDNACAQTGVNRFLHINDAWTYNKTENLKPADLENFDFLVLGTYGNTLKTEVESKFVTWHRPLFFVNSFHQYKIKKSRQFPWIYPEIIYTEKAVVLKNRNYK

Gene Information

Entrez Gene ID
179185
Gene Name
Protein ZC513.5
Gene Symbol
CELE_ZC513.5
Species
Caenorhabditis elegans

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005783 ISS:UniProtKB C endoplasmic reticulum
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0000009 ISS:UniProtKB F alpha-1,6-mannosyltransferase activity
GO:0052917 IEA:UniProtKB-EC F dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase activity
GO:0006488 ISS:UniProtKB P dolichol-linked oligosaccharide biosynthetic process
GO:0097502 ISS:GOC P mannosylation
GO:0006486 ISS:UniProtKB P protein glycosylation

KEGG Pathway Links

KEGG Pathway ID Description
cel01100 Metabolic pathways
cel00510 N-Glycan biosynthesis
ko00510 N-Glycan biosynthesis

REACTOME Pathway Links

REACTOME Pathway ID Description
5652981 Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein

Domain Information

InterPro Annotations

Accession Description
IPR005599 GPI mannosyltransferase

UniProt Annotations

Entry Information

Gene Name
Protein ZC513.5
Protein Entry
ALG12_CAEEL
UniProt ID
Q23361
Species
C. elegans

Comments

Comment Type Description
Catalytic Activity Dolichyl beta-D-mannosyl phosphate + D-Man- alpha-(1->2)-D-Man-alpha-(1->2)-D-Man-alpha-(1->3)-(D-Man-alpha- (1->2)-D-Man-alpha-(1->3)-D-Man-alpha-(1->6))-D-Man-beta-(1->4)-D- GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol = D-Man-alpha- (1->2)-D-Man-alpha-(1->2)-D-Man-alpha-(1->3)-(D-Man-alpha-(1->2)- D-Man-alpha-(1->3)-(D-Man-alpha-(1->6))-D-Man-alpha-(1->6))-D-Man- beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol + dolichyl phosphate.
Function Adds the eighth mannose residue in an alpha-1,6 linkage onto the dolichol-PP-oligosaccharide precursor (dolichol-PP- Man(7)GlcNAc(2)) required for protein glycosylation. {ECO:0000250}.
Pathway Protein modification; protein glycosylation.
Similarity Belongs to the glycosyltransferase 22 family. {ECO:0000305}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.

Identical and Related Proteins

Unique RefSeq proteins for LMP008013 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
17566740 RefSeq NP_505071 492 Protein ZC513.5

Identical Sequences to LMP008013 proteins

Reference Database Accession Length Protein Name
GI:17566740 EMBL CCD64068.1 492 Protein ZC513.5 [Caenorhabditis elegans]
GI:17566740 SwissProt Q23361.2 492 RecName: Full=Probable Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase; AltName: Full=Asparagine-linked glycosylation protein 12 homolog; AltName: Full=Dolichyl-P-Man:Man(7)GlcNAc(2)-PP-dolichyl-alpha-1,6-mannosyltransferase; AltName: Full=Mannosyltransferase ALG12 homolog [Caenorhabditis elegans]

Related Sequences to LMP008013 proteins

Reference Database Accession Length Protein Name
GI:17566740 EMBL CAP30572.2 604 Protein CBG11382 [Caenorhabditis briggsae]
GI:17566740 EMBL CDJ81963.1 491 Alg9 mannosyltransferase domain containing protein [Haemonchus contortus]
GI:17566740 GenBank EFO87966.1 492 hypothetical protein CRE_05469 [Caenorhabditis remanei]
GI:17566740 GenBank EGT32114.1 408 hypothetical protein CAEBREN_31706 [Caenorhabditis brenneri]
GI:17566740 RefSeq XP_002635153.1 454 Hypothetical protein CBG11382, partial [Caenorhabditis briggsae]
GI:17566740 RefSeq XP_003110673.1 492 hypothetical protein CRE_05469 [Caenorhabditis remanei]