Gene/Proteome Database (LMPD)

LMPD ID
LMP008072
Gene ID
184910
Species
Caenorhabditis elegans (C. elegans)
Gene Name
Protein CRLS-1
Gene Symbol
crls-1
Synonyms
CELE_F23H11.9
Chromosome
III
EC Number
2.7.8.-;

Proteins

Protein CRLS-1, isoform a
Refseq ID NP_001022546
Protein GI 71984834
UniProt ID O01916
mRNA ID NM_001027375
Length 246
MIVTSMFRGIACRCELQLLLTPRRMLRNFSSLEQKQSPKIESLPPEERGKYKVATIPNAICTARIAATPLIGYLVVQHNFTPAFVLFTVAGATDLLDGFIARNVPGQKSLLGSVLDPVADKLLISTMFITMTYAGLIPLPLTSVVILRDICLIGGGFYKRYQVMSPPYSLSRFFNPQVSSMQVVPTMMSKINTVLQITLVALSLSSPVFDFSTGANDVIVGLGCITGFTTIYSGLQYASGKAIKKI
Protein CRLS-1, isoform b
Refseq ID NP_001022547
Protein GI 71984838
UniProt ID O01916
mRNA ID NM_001027376
Length 222
MLRNFSSLEQKQSPKIESLPPEERGKYKVATIPNAICTARIAATPLIGYLVVQHNFTPAFVLFTVAGATDLLDGFIARNVPGQKSLLGSVLDPVADKLLISTMFITMTYAGLIPLPLTSVVILRDICLIGGGFYKRYQVMSPPYSLSRFFNPQVSSMQVVPTMMSKINTVLQITLVALSLSSPVFDFSTGANDVIVGLGCITGFTTIYSGLQYASGKAIKKI

Gene Information

Entrez Gene ID
184910
Gene Name
Protein CRLS-1
Gene Symbol
crls-1
Species
Caenorhabditis elegans

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0005743 IEA:UniProtKB-KW C mitochondrial inner membrane
GO:0005739 ISS:WormBase C mitochondrion
GO:0008808 IMP:WormBase F cardiolipin synthase activity
GO:0032049 IMP:WormBase P cardiolipin biosynthetic process
GO:0042127 IMP:WormBase P regulation of cell proliferation
GO:0051881 IMP:WormBase P regulation of mitochondrial membrane potential

KEGG Pathway Links

KEGG Pathway ID Description
cel00564 Glycerophospholipid metabolism
ko00564 Glycerophospholipid metabolism
cel01100 Metabolic pathways

REACTOME Pathway Links

REACTOME Pathway ID Description
5653398 Acyl chain remodelling of PG
5652685 Glycerophospholipid biosynthesis
5652491 Metabolism
5652530 Metabolism of lipids and lipoproteins
5652686 Phospholipid metabolism
5653408 Synthesis of CL

Domain Information

InterPro Annotations

Accession Description
IPR000462 CDP-alcohol phosphatidyltransferase

UniProt Annotations

Entry Information

Gene Name
Protein CRLS-1
Protein Entry
CRLS1_CAEEL
UniProt ID
O01916
Species
C. elegans

Comments

Comment Type Description
Alternative Products Event=Alternative splicing; Named isoforms=2; Name=a; IsoId=O01916-1; Sequence=Displayed; Note=No experimental confirmation available.; Name=b; IsoId=O01916-2; Sequence=VSP_015561; Note=No experimental confirmation available.;
Alternative Products Event=Alternative splicing; Named isoforms=2; Name=a; IsoId=O01916-1; Sequence=Displayed; Note=No experimental confirmation available.; Name=b; IsoId=O01916-2; Sequence=VSP_015561; Note=No experimental confirmation available.;
Catalytic Activity 2 Phosphatidylglycerol = diphosphatidylglycerol + glycerol.
Function Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Function Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. {ECO:0000250}.
Similarity Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Similarity Belongs to the CDP-alcohol phosphatidyltransferase class-I family. {ECO:0000305}.
Subcellular Location Mitochondrion inner membrane ; Multi-pass membrane protein .
Subcellular Location Mitochondrion inner membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.

Identical and Related Proteins

Unique RefSeq proteins for LMP008072 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
71984834 RefSeq NP_001022546 246 Protein CRLS-1, isoform a
71984838 RefSeq NP_001022547 222 Protein CRLS-1, isoform b

Identical Sequences to LMP008072 proteins

Reference Database Accession Length Protein Name

Related Sequences to LMP008072 proteins

Reference Database Accession Length Protein Name