Gene/Proteome Database (LMPD)

LMPD ID
LMP008174
Gene ID
175998
Species
Caenorhabditis elegans (C. elegans)
Gene Name
Protein GGTB-1
Gene Symbol
ggtb-1
Synonyms
CELE_B0280.1
Alternate Names
Protein GGTB-1
Chromosome
III
EC Number
2.5.1.60

Proteins

Protein GGTB-1, isoform a
Refseq ID NP_498559
Protein GI 17551754
UniProt ID P41992
mRNA ID NM_066158
Length 335
RefSeq Status REVIEWED
MSFAGLLDFARKDVDLPQNSPNELLKDLHANFINQYEKNKNSYHYIMAEHLRVSGIYWCVNAMDLSKQLERMSTEEIVNYVLGCRNTDGGYGPAPGHDSHLLHTLCAVQTLIIFNSIEKADADTISEYVKGLQQEDGSFCGDLSGEVDTRFTLCSLATCHLLGRLSTLNIDSAVRFLMRCYNTDGGFGTRPGSESHSGQIYCCVGALAIAGRLDEIDRDRTAEWLAFRQCDSGGLNGRPEKLPDVCYSWWVLASLAILGRLNFIDSDAMKKFIYACQDDETGGFADRPGDCADPFHTVFGIAALSLFGDDTLESVDPIFCMTKRCLGDKQVEMYY
Protein GGTB-1, isoform b
Refseq ID NP_741214
Protein GI 115535166
UniProt ID P41992
mRNA ID NM_171183
Length 325
RefSeq Status REVIEWED
MSFAGLLDFARKDVDLPQNSPNELLKDLHANFINQYEKNKNSYHYIMAEHLRVSGIYWCVNAMDLSKQLERMSTEEIVNYVLGCRNTDGGYGPAPGHDSHLLHTLCAVQTLIIFNSIEKADADTISEYVKGLQQEDGSFCGDLSGEVDTRFTLCSLATCHLLGRLSTLNIDSAVRFLMRCYNTDGGFGTRPGSESHSGQIYCCVGALAIAGRLDEIDRDRTAEWLAFRQCDSGGLNGRPEKLPDVCYSWWVLASLAILGRLNFIDSDAMKKFIYACQDDETGGFADRPGDCVSFLNNIQKFIFVLQSNNVLATTKQLFECSFNNS

Gene Information

Entrez Gene ID
175998
Gene Name
Protein GGTB-1
Gene Symbol
ggtb-1
Species
Caenorhabditis elegans

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005968 ISS:UniProtKB C Rab-protein geranylgeranyltransferase complex
GO:0017137 ISS:UniProtKB F Rab GTPase binding
GO:0004663 ISS:UniProtKB F Rab geranylgeranyltransferase activity
GO:0008270 ISS:UniProtKB F zinc ion binding
GO:0018344 ISS:UniProtKB P protein geranylgeranylation

Domain Information

InterPro Annotations

Accession Description
IPR026873 Geranylgeranyl transferase type-2 subunit beta
IPR001330 Prenyltransferase/squalene oxidase
IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid

UniProt Annotations

Entry Information

Gene Name
Protein GGTB-1
Protein Entry
GGTB2_CAEEL
UniProt ID
P41992
Species
C. elegans

Comments

Comment Type Description
Alternative Products Event=Alternative splicing; Named isoforms=2; Name=a; IsoId=P41992-1; Sequence=Displayed; Note=No experimental confirmation available.; Name=b; IsoId=P41992-2; Sequence=VSP_018160; Note=No experimental confirmation available.;
Catalytic Activity Geranylgeranyl diphosphate + protein-cysteine = S-geranylgeranyl-protein + diphosphate.
Cofactor Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence={ECO:0000250}; Note=Binds 1 zinc ion per subunit. {ECO:0000250};
Function Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to both cysteines in Rab proteins with an -XXCC, -XCXC and -CCXX C-terminal. {ECO:0000250}.
Similarity Belongs to the protein prenyltransferase subunit beta family. {ECO:0000305}.
Similarity Contains 5 PFTB repeats. {ECO:0000305}.
Subunit Heterodimer of an alpha and a beta subunit. {ECO:0000250}.

Identical and Related Proteins

Unique RefSeq proteins for LMP008174 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
17551754 RefSeq NP_498559 335 Protein GGTB-1, isoform a
115535166 RefSeq NP_741214 325 Protein GGTB-1, isoform b

Identical Sequences to LMP008174 proteins

Reference Database Accession Length Protein Name
GI:17551754 EMBL CCD61597.1 335 Protein GGTB-1, isoform a [Caenorhabditis elegans]
GI:115535166 EMBL CCD61598.1 325 Protein GGTB-1, isoform b [Caenorhabditis elegans]
GI:115535166 GenBank ABZ31832.1 325 Sequence 5770 from patent US 7314974
GI:115535166 PIR - 325 hypothetical protein B0280.1 - Caenorhabditis elegans [Caenorhabditis elegans]
GI:17551754 SwissProt P41992.2 335 RecName: Full=Probable geranylgeranyl transferase type-2 subunit beta; AltName: Full=Geranylgeranyl transferase type II subunit beta; Short=GGTase-II-beta; AltName: Full=Rab geranyl-geranyltransferase subunit beta; Short=Rab GG transferase beta; Short=Rab GGTase beta; AltName: Full=Rab geranylgeranyltransferase subunit beta; AltName: Full=Type II protein geranyl-geranyltransferase subunit beta [Caenorhabditis elegans]

Related Sequences to LMP008174 proteins

Reference Database Accession Length Protein Name
GI:17551754 EMBL CAP34523.2 371 Protein CBR-GGTB-1 [Caenorhabditis briggsae]
GI:115535166 EMBL CAP34523.2 371 Protein CBR-GGTB-1 [Caenorhabditis briggsae]
GI:115535166 EMBL CCD61597.1 335 Protein GGTB-1, isoform a [Caenorhabditis elegans]
GI:17551754 EMBL CCD61598.1 325 Protein GGTB-1, isoform b [Caenorhabditis elegans]
GI:17551754 GenBank ABZ31832.1 325 Sequence 5770 from patent US 7314974
GI:17551754 PIR - 325 hypothetical protein B0280.1 - Caenorhabditis elegans [Caenorhabditis elegans]
GI:115535166 RefSeq NP_498559.1 335 Protein GGTB-1, isoform a [Caenorhabditis elegans]
GI:17551754 RefSeq NP_741214.2 325 Protein GGTB-1, isoform b [Caenorhabditis elegans]
GI:115535166 RefSeq XP_002641906.1 371 Hypothetical protein CBG16602 [Caenorhabditis briggsae]
GI:17551754 RefSeq XP_002641906.1 371 Hypothetical protein CBG16602 [Caenorhabditis briggsae]
GI:115535166 RefSeq XP_003113335.1 316 CRE-GGTB-1 protein [Caenorhabditis remanei]
GI:115535166 SwissProt P41992.2 335 RecName: Full=Probable geranylgeranyl transferase type-2 subunit beta; AltName: Full=Geranylgeranyl transferase type II subunit beta; Short=GGTase-II-beta; AltName: Full=Rab geranyl-geranyltransferase subunit beta; Short=Rab GG transferase beta; Short=Rab GGTase beta; AltName: Full=Rab geranylgeranyltransferase subunit beta; AltName: Full=Type II protein geranyl-geranyltransferase subunit beta [Caenorhabditis elegans]