Gene/Proteome Database (LMPD)

LMPD ID
LMP008277
Gene ID
179217
Species
Caenorhabditis elegans (C. elegans)
Gene Name
Protein MOM-2
Gene Symbol
mom-2
Synonyms
CELE_F38E1.7
Alternate Names
Protein MOM-2
Chromosome
V

Proteins

Protein MOM-2
Refseq ID NP_505154
Protein GI 17562714
UniProt ID Q10459
mRNA ID NM_072753
Length 362
RefSeq Status REVIEWED
MHINTPVLLAIIYFLVFAPKSADAWWLLSKTDTSSANSGSSPILCKNVPGLTPQQKRMCHENPNIIKYLISGLRSALHTCEYTFQREAWNCTLTLPGVGTSPLQIASRESAYVYAISAAGVSHSLARACSKGLIDDCGCGETPQGSGSVAVSQASSRSSSDFVWAGCSDNVKFGNTFGRKFVDQYDRQHATEPRSQMNLHNNRVGRRLLVNAMNKECKCHGVSGSCVTKTCWKVMPKFDEFASRLHQKYQLAKLVTNNDQKLTVRSSPSAGSSGRSERFARNMDASSKQMRNELIYLDASPNYCAIDVKDRECGENCPNICCGRGWRTTREIVDEPCHCQFVWCCEVKCKTCKKLVERNYCL

Gene Information

Entrez Gene ID
179217
Gene Name
Protein MOM-2
Gene Symbol
mom-2
Species
Caenorhabditis elegans

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005576 ISS:WormBase C extracellular region
GO:0005615 IBA:RefGenome C extracellular space
GO:0005578 IEA:UniProtKB-KW C proteinaceous extracellular matrix
GO:0005109 ISS:WormBase F frizzled binding
GO:0030971 IPI:WormBase F receptor tyrosine kinase binding
GO:0016055 ISS:WormBase P Wnt signaling pathway
GO:0045167 IMP:WormBase P asymmetric protein localization involved in cell fate determination
GO:0048598 IMP:WormBase P embryonic morphogenesis
GO:0001714 IMP:WormBase P endodermal cell fate specification
GO:0030010 IMP:WormBase P establishment of cell polarity
GO:0000132 IMP:WormBase P establishment of mitotic spindle orientation
GO:0030182 IBA:RefGenome P neuron differentiation

KEGG Pathway Links

KEGG Pathway ID Description
cel04340 Hedgehog signaling pathway
cel04310 Wnt signaling pathway

Domain Information

InterPro Annotations

Accession Description
IPR005817 Wnt
IPR018161 Wnt protein, conserved site

UniProt Annotations

Entry Information

Gene Name
Protein MOM-2
Protein Entry
MOM2_CAEEL
UniProt ID
Q10459
Species
C. elegans

Comments

Comment Type Description
Function Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein involved in endoderm specification and cleavage axis determination.
Similarity Belongs to the Wnt family. {ECO:0000305}.
Subcellular Location Secreted, extracellular space, extracellular matrix.

Identical and Related Proteins

Unique RefSeq proteins for LMP008277 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
17562714 RefSeq NP_505154 362 Protein MOM-2

Identical Sequences to LMP008277 proteins

Reference Database Accession Length Protein Name
GI:17562714 EMBL CCD63659.1 362 Protein MOM-2 [Caenorhabditis elegans]
GI:17562714 GenBank AAC47749.1 362 endoderm specification; cleavage axis determination [Caenorhabditis elegans]
GI:17562714 SwissProt Q10459.2 362 RecName: Full=Protein mom-2; Flags: Precursor [Caenorhabditis elegans]

Related Sequences to LMP008277 proteins

Reference Database Accession Length Protein Name
GI:17562714 EMBL CAP30657.1 358 Protein CBR-MOM-2 [Caenorhabditis briggsae]
GI:17562714 GenBank EFO87897.1 366 CRE-MOM-2 protein [Caenorhabditis remanei]
GI:17562714 GenBank EGT57433.1 367 hypothetical protein CAEBREN_28048 [Caenorhabditis brenneri]
GI:17562714 GenBank EGT60517.1 347 CBN-MOM-2 protein [Caenorhabditis brenneri]
GI:17562714 RefSeq XP_002635068.1 358 C. briggsae CBR-MOM-2 protein [Caenorhabditis briggsae]
GI:17562714 RefSeq XP_003110604.1 366 CRE-MOM-2 protein [Caenorhabditis remanei]