Gene/Proteome Database (LMPD)
Proteins
| Protein PKC-2, isoform a | |
|---|---|
| Refseq ID | NP_001024516 |
| Protein GI | 71986421 |
| UniProt ID | P90980 |
| mRNA ID | NM_001029345 |
| Length | 680 |
| RefSeq Status | REVIEWED |
| MSLSTNSSVKEDEAQRIEGKAFVRRGALRQKNVHEIKSHKFIARFFKQPTFCSHCKDFLWGITKQGFQCQVCTLVVHKRCHEFVNFACPGADKGVDTDDPRQQHKWKVQTYSSPTFCDHCGSLLYGILHQGMKCQSCDTNVHHRCVKNVPNMCGTDNTEKRGRLRIEAHIENDQLTIKILEAKNLIPMDPNGLSDPYVKCKLIPEDSGCKSKQKTKTLRATLNPQWNETFTYKLLPGDKDRRLSIEVWDWDRTSRNDFMGSLSFGISELMKEAASGWYKLLSAEEGEFYNINITPEYDEDMEKVRKKMNENFITRDNSSSKPKDPAAPRASTLPLGSSNHNVIKASDFNFLTVLGKGSFGKVLLGEQKTTKELFAIKVLKKDVIIQDDDVECTMTEKRVLALPEKPSFLVALHSCFQTMDRLYFVMEFVNGGDLMYQIQQVGKFKEPVAVFYAAEIAVGLFFLHSKGIIYRDLKLDNVMLERDGHIKITDFGMCKENIFGDATTKTFCGTPDYIAPEIILYQPYGKSVDWWAYGVLLFEMLAGQPPFDGEDEDELFTAITEHNVSYPKSLSKEAVSLCKALLIKNPSKRLGCTGDDESASRDIKEHPFFRRIDWFKIETRQIQPPFKPKLKSADDTSNFDSEFTHEVPKLTPIDRLFLMNLDQTEFEGFSFVNPEYVQEC | |
| Protein PKC-2, isoform b | |
|---|---|
| Refseq ID | NP_001024517 |
| Protein GI | 71986426 |
| UniProt ID | P90980 |
| mRNA ID | NM_001029346 |
| Length | 682 |
| RefSeq Status | REVIEWED |
| MSLSTNSSVKEDEAQRIEGKAFVRRGALRQKNVHEIKSHKFIARFFKQPTFCSHCKDFLWGITKQGFQCQVCTLVVHKRCHEFVNFACPGADKGVDTDDPRQQHKWKVQTYSSPTFCDHCGSLLYGILHQGMKCQSCDTNVHHRCVKNVPNMCGTDNTEKRGRLRIEAHIENDQLTIKILEAKNLIPMDPNGLSDPYVKCKLIPEDSGCKSKQKTKTLRATLNPQWNETFTYKLLPGDKDRRLSIEVWDWDRTSRNDFMGSLSFGISELMKEAASGWYKLLSAEEGEFYNINITPEYDEDMEKVRKKMNENFITRDNSSSKPKDPAAPRASTLPLGSSNHNVIKASDFNFLTVLGKGSFGKVLLGEQKTTKELFAIKVLKKDVIIQDDDVECTMTEKRVLALPEKPSFLVALHSCFQTMDRLYFVMEFVNGGDLMYQIQQVGKFKEPVAVFYAAEIAVGLFFLHSKGIIYRDLKLDNVMLERDGHIKITDFGMCKENIFGDATTKTFCGTPDYIAPEIILYQPYGKSVDWWAYGVLLFEMLAGQPPFDGEDEDELFTAITEHNVSYPKSLSKEAVSLCKALLIKNPSKRLGCTGDDESASRDIKEHPFFRRIDWFKIETRQIQPPFKPKLKTDRSTENFDHSFLKLPTKMTPPDWEVLENLKGDEFSNFSFVNPFYVKDVEP | |
| Protein PKC-2, isoform c | |
|---|---|
| Refseq ID | NP_001024518 |
| Protein GI | 71986433 |
| UniProt ID | P90980 |
| mRNA ID | NM_001029347 |
| Length | 936 |
| RefSeq Status | REVIEWED |
| MSLRPKQKSSSTSVFLKSHKFSLTSHILRKAKKRETMDSAERRRSETDIGGGPRNSADARPSLDLSSDPMLESNLALRKLSEAFAAAALISPVKNNSTGGGGNQQLCIRKSISNPSSLKVYAHHEAPGIIHFPRFEFSHRLSIRPLLKRLHEQAQRIEGKAFVRRGALRQKNVHEIKSHKFIARFFKQPTFCSHCKDFLWGITKQGFQCQVCTLVVHKRCHEFVNFACPGADKGVDTDDPRQQHKWKVQTYSSPTFCDHCGSLLYGILHQGMKCQSCDTNVHHRCVKNVPNMCGTDNTEKRGRLRIEAHIENDQLTIKILEAKNLIPMDPNGLSDPYVKCKLIPEDSGCKSKQKTKTLRATLNPQWNETFTYKLLPGDKDRRLSIEVWDWDRTSRNDFMGSLSFGISELMKEAASGWYKLLSAEEGEFYNINITPEYDEDMEKVRKKMNENFITRDNSSSKPKDPAAPRASTLPLGSSNHNVIKASDFNFLTVLGKGSFGKVLLGEQKTTKELFAIKVLKKDVIIQDDDVECTMTEKRVLALPEKPSFLVALHSCFQTMDRLYFVMEFVNGGDLMYQIQQVGKFKEPVAVFYAAEIAVGLFFLHSKGIIYRDLKLDNVMLERDGHIKITDFGMCKENIFGDATTKTFCGTPDYIAPEIILYQPYGKSVDWWAYGVLLFEMLAGQPPFDGEDEDELFTAITEHNVSYPKSLSKEAVSLCKALLIKNPSKRLGCTGDDESASRDIKEHPFFRRIDWFKIETRQIQPPFKPKLKTDRSTENFDHSFLKLPTKMTPPDWEVLENLKGDEFSNFSFVNPFYVKDVEPHIFYVLFIFLILRPFLLLPYLSHLQLTLSAIHSPLLLLSASVFFKFLFKNNFSQSPYNKIKVLLKSADDTSNFDSEFTHEVPKLTPIDRLFLMNLDQTEFEGFSFVNPEYVQEC | |
| Protein PKC-2, isoform d | |
|---|---|
| Refseq ID | NP_001123122 |
| Protein GI | 193209737 |
| UniProt ID | G8JY36 |
| mRNA ID | NM_001129650 |
| Length | 725 |
| RefSeq Status | REVIEWED |
| MHRSDESRMSFEHRSVVRLFSNSSTTSNGSRKTSVPSAVLASAPLMSAAIGDGLGTQLSQRIEGKAFVRRGALRQKNVHEIKSHKFIARFFKQPTFCSHCKDFLWGITKQGFQCQVCTLVVHKRCHEFVNFACPGADKGVDTDDPRQQHKWKVQTYSSPTFCDHCGSLLYGILHQGMKCQSCDTNVHHRCVKNVPNMCGTDNTEKRGRLRIEAHIENDQLTIKILEAKNLIPMDPNGLSDPYVKCKLIPEDSGCKSKQKTKTLRATLNPQWNETFTYKLLPGDKDRRLSIEVWDWDRTSRNDFMGSLSFGISELMKEAASGWYKLLSAEEGEFYNINITPEYDEDMEKVRKKMNENFITRDNSSSKPKDPAAPRASTLPLGSSNHNVIKASDFNFLTVLGKGSFGKVLLGEQKTTKELFAIKVLKKDVIIQDDDVECTMTEKRVLALPEKPSFLVALHSCFQTMDRLYFVMEFVNGGDLMYQIQQVGKFKEPVAVFYAAEIAVGLFFLHSKGIIYRDLKLDNVMLERDGHIKITDFGMCKENIFGDATTKTFCGTPDYIAPEIILYQPYGKSVDWWAYGVLLFEMLAGQPPFDGEDEDELFTAITEHNVSYPKSLSKEAVSLCKALLIKNPSKRLGCTGDDESASRDIKEHPFFRRIDWFKIETRQIQPPFKPKLKSADDTSNFDSEFTHEVPKLTPIDRLFLMNLDQTEFEGFSFVNPEYVQEC | |
Gene Information
Gene Ontology (GO Annotations)
| GO ID | Source | Type | Description |
|---|---|---|---|
| GO:0005829 | IDA:WormBase | C | cytosol |
| GO:0016020 | IDA:WormBase | C | membrane |
| GO:0043005 | IDA:WormBase | C | neuron projection |
| GO:0043025 | IDA:WormBase | C | neuronal cell body |
| GO:0005524 | IEA:UniProtKB-KW | F | ATP binding |
| GO:0004698 | IDA:WormBase | F | calcium-dependent protein kinase C activity |
| GO:0004697 | IDA:WormBase | F | protein kinase C activity |
| GO:0008270 | IEA:InterPro | F | zinc ion binding |
| GO:0035556 | IEA:InterPro | P | intracellular signal transduction |
| GO:0018105 | IDA:WormBase | P | peptidyl-serine phosphorylation |
| GO:0018107 | ISS:WormBase | P | peptidyl-threonine phosphorylation |
Domain Information
InterPro Annotations
| Accession | Description |
|---|---|
| IPR000961 | AGC-kinase, C-terminal |
| IPR000008 | C2 domain |
| IPR020454 | Diacylglycerol/phorbol-ester binding |
| IPR014375 | Protein kinase C, alpha/beta/gamma types |
| IPR002219 | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain |
| IPR000719 | Protein kinase domain |
| IPR017441 | Protein kinase, ATP binding site |
| IPR017892 | Protein kinase, C-terminal |
| IPR011009 | Protein kinase-like domain |
| IPR008271 | Serine/threonine-protein kinase, active site |
| IPR002290 | Serine/threonine/dual specificity protein kinase, catalytic domain |
UniProt Annotations
Entry Information
Comments
| Comment Type | Description |
|---|---|
| Catalytic Activity | ATP + a protein = ADP + a phosphoprotein. |
| Similarity | Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. |
| Similarity | Contains 1 C2 domain. |
| Similarity | Contains AGC-kinase C-terminal domain. |
| Similarity | Contains protein kinase domain. |
Identical and Related Proteins
Unique RefSeq proteins for LMP008327 (as displayed in Record Overview)
| Protein GI | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| 71986421 | RefSeq | NP_001024516 | 680 | Protein PKC-2, isoform a |
| 71986426 | RefSeq | NP_001024517 | 682 | Protein PKC-2, isoform b |
| 71986433 | RefSeq | NP_001024518 | 936 | Protein PKC-2, isoform c |
| 193209737 | RefSeq | NP_001123122 | 725 | Protein PKC-2, isoform d |
Identical Sequences to LMP008327 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:71986421 | EMBL | CCD65287.1 | 680 | Protein PKC-2, isoform a [Caenorhabditis elegans] |
| GI:71986426 | EMBL | CCD65288.1 | 682 | Protein PKC-2, isoform b [Caenorhabditis elegans] |
| GI:71986433 | EMBL | CCD65289.1 | 936 | Protein PKC-2, isoform c [Caenorhabditis elegans] |
| GI:193209737 | EMBL | CCD65291.1 | 725 | Protein PKC-2, isoform d [Caenorhabditis elegans] |
| GI:71986426 | SwissProt | P90980.2 | 682 | RecName: Full=Protein kinase C-like 2; Short=PKC2 [Caenorhabditis elegans] |
Related Sequences to LMP008327 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:71986433 | EMBL | CAP34244.2 | 941 | Protein CBR-PKC-2 [Caenorhabditis briggsae] |
| GI:193209737 | EMBL | CCD65287.1 | 680 | Protein PKC-2, isoform a [Caenorhabditis elegans] |
| GI:71986426 | EMBL | CCD65287.1 | 680 | Protein PKC-2, isoform a [Caenorhabditis elegans] |
| GI:71986421 | EMBL | CCD65288.1 | 682 | Protein PKC-2, isoform b [Caenorhabditis elegans] |
| GI:71986426 | EMBL | CCD65289.1 | 936 | Protein PKC-2, isoform c [Caenorhabditis elegans] |
| GI:71986421 | EMBL | CCD65291.1 | 725 | Protein PKC-2, isoform d [Caenorhabditis elegans] |
| GI:71986421 | GenBank | AAB40868.1 | 680 | protein kinase C2 A isoform [Caenorhabditis elegans] |
| GI:193209737 | GenBank | AAB40868.1 | 680 | protein kinase C2 A isoform [Caenorhabditis elegans] |
| GI:71986426 | GenBank | AAB40869.1 | 682 | protein kinase C2 B isoform [Caenorhabditis elegans] |
| GI:71986433 | GenBank | ABZ32916.1 | 861 | Sequence 6854 from patent US 7314974 |
| GI:71986426 | GenBank | ABZ32916.1 | 861 | Sequence 6854 from patent US 7314974 |
| GI:71986433 | GenBank | EFO97309.1 | 882 | CRE-PKC-2 protein [Caenorhabditis remanei] |
| GI:193209737 | GenBank | EGT58150.1 | 745 | CBN-PKC-2 protein [Caenorhabditis brenneri] |
| GI:71986433 | PIR | - | 861 | protein kinase C homolog - Caenorhabditis elegans [Caenorhabditis elegans] |
| GI:71986426 | PIR | - | 861 | protein kinase C homolog - Caenorhabditis elegans [Caenorhabditis elegans] |
| GI:193209737 | RefSeq | NP_001024516.1 | 680 | Protein PKC-2, isoform a [Caenorhabditis elegans] |
| GI:71986421 | RefSeq | NP_001024517.1 | 682 | Protein PKC-2, isoform b [Caenorhabditis elegans] |
| GI:193209737 | RefSeq | NP_001024517.1 | 682 | Protein PKC-2, isoform b [Caenorhabditis elegans] |
| GI:71986426 | RefSeq | NP_001024518.1 | 936 | Protein PKC-2, isoform c [Caenorhabditis elegans] |
| GI:71986421 | RefSeq | NP_001123122.1 | 725 | Protein PKC-2, isoform d [Caenorhabditis elegans] |
| GI:71986433 | RefSeq | XP_002643485.1 | 941 | C. briggsae CBR-PKC-2 protein [Caenorhabditis briggsae] |
| GI:71986433 | RefSeq | XP_003106703.1 | 882 | CRE-PKC-2 protein [Caenorhabditis remanei] |
| GI:71986421 | SwissProt | P90980.2 | 682 | RecName: Full=Protein kinase C-like 2; Short=PKC2 [Caenorhabditis elegans] |
| GI:193209737 | SwissProt | P90980.2 | 682 | RecName: Full=Protein kinase C-like 2; Short=PKC2 [Caenorhabditis elegans] |