Gene/Proteome Database (LMPD)

LMPD ID
LMP008787
Gene ID
31899
Species
Drosophila melanogaster (Drosophila)
Gene Name
CG32699 gene product from transcript CG32699-RB
Gene Symbol
CG32699
Synonyms
CG15318; CG18535; CG2996; CT7882; Dmel\CG32699; tok-like
Chromosome
X
Map Location
8E10-8E10

Proteins

CG32699
Refseq ID NP_001036265
Protein GI 116007140
UniProt ID Q0KHU5
mRNA ID NM_001042800
Length 533
RefSeq Status REVIEWED
MTTSTIKPTGGDEVPPAGVVGNVADVGVAASLTKRDSEEDTWASKGYNYINPFVHRIEIDSHIEVAKIYVLTVLLLPIRVVGCVLSLISAWMFACIGLYGMTLDDLKAKPLTGWRKQMQYMTACGMRMVYTFGSFHYVTMKGRAATAKEAPILVVAPHSSYVDSILVVASGPPSIVAKRETADIPLLGKIINYAQPIYVQREDPNSRQNTIRDIVDRARSTDDWPQVVIFAEGTCTNRTALIKFKPGAFYPGVPVQPVLLKYPNKYDTFTWTWDGPGVLRLLWLTMTQFYNRCEIEYLPVYTPSEDEVADANLYANNVREVMAKALGVPTSDYSFEDVIVMSRARDMKIPFPGDIVEIERTIEKLGLNESQRDAELCKGFLRLSNTDRLDIITFGELLQVDLKNTDLHKLFALLDHRRSGTVSLKSFLLCSLFCKLKNSDLLTFLRALIHLYSESSQQIDRESFVRLMRHAGGKLNEQKAQALFYALDTDNLGYVSFDSFVELTEKQKSSYKFLYHKSEHIRRPKAVVTTAEN

Gene Information

Entrez Gene ID
31899
Gene Name
CG32699 gene product from transcript CG32699-RB
Gene Symbol
CG32699
Species
Drosophila melanogaster

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005794 ISS:UniProtKB C Golgi apparatus
GO:0005783 ISS:UniProtKB C endoplasmic reticulum
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0047184 ISS:UniProtKB F 1-acylglycerophosphocholine O-acyltransferase activity
GO:0005509 IEA:InterPro F calcium ion binding
GO:0008654 ISS:UniProtKB P phospholipid biosynthetic process

Domain Information

InterPro Annotations

Accession Description
IPR002048 EF-hand domain
IPR011992 EF-hand domain pair
IPR002123 Phospholipid/glycerol acyltransferase

UniProt Annotations

Entry Information

Gene Name
CG32699 gene product from transcript CG32699-RB
Protein Entry
Q0KHU5_DROME
UniProt ID
Q0KHU5
Species
Drosophila

Comments

Comment Type Description
Alternative Products Event=Alternative splicing; Named isoforms=2; Name=B ; IsoId=Q0KHU5-1; Sequence=Displayed; Note=No experimental confirmation available. ; Name=A ; IsoId=Q0KHU5-2; Sequence=VSP_052338; Note=No experimental confirmation available. ;
Catalytic Activity Acyl-CoA + 1-acyl-sn-glycero-3-phosphocholine = CoA + 1,2-diacyl-sn-glycero-3-phosphocholine.
Domain The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphocholine.
Function Acetyltransferase which mediates the conversion of 1- acyl-sn-glycero-3-phosphocholine (LPC) into phosphatidylcholine (PC). Has a calcium-independent activity. Displays a clear preference for saturated fatty acyl-CoAs, and 1-myristoyl or 1- palmitoyl LPC as acyl donors and acceptors, respectively (By similarity).
Pathway Lipid metabolism; phospholipid metabolism.
Rna Editing Modified_positions=175 {ECO:0000269|PubMed:17018572, ECO:0000269|Ref.3}; Note=Partially edited. Target of Adar. ;
Sequence Caution Sequence=AAL28380.1; Type=Erroneous initiation; Evidence= ;
Similarity Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
Similarity Contains 3 EF-hand domains. {ECO:0000255|PROSITE- ProRule:PRU00448}.
Subcellular Location Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus membrane ; Single-pass type II membrane protein .

Identical and Related Proteins

Unique RefSeq proteins for LMP008787 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
116007140 RefSeq NP_001036265 533 CG32699

Identical Sequences to LMP008787 proteins

Reference Database Accession Length Protein Name
GI:116007140 gnl FlyBase 533 CG32699 [Drosophila melanogaster]
GI:116007140 SwissProt Q0KHU5.1 533 RecName: Full=1-acylglycerophosphocholine O-acyltransferase 1; AltName: Full=Acyltransferase-like 2 [Drosophila melanogaster]

Related Sequences to LMP008787 proteins

Reference Database Accession Length Protein Name
GI:116007140 GenBank AAO39597.1 533 HL01250p [Drosophila melanogaster]
GI:116007140 GenBank EDV35204.1 558 GF22630 [Drosophila ananassae]
GI:116007140 GenBank EDW45632.1 452 GM11357 [Drosophila sechellia]
GI:116007140 RefSeq XP_001965689.1 558 GF22630 [Drosophila ananassae]
GI:116007140 RefSeq XP_001977313.1 474 GG18969 [Drosophila erecta]
GI:116007140 RefSeq XP_002041784.1 452 GM11357 [Drosophila sechellia]