Gene/Proteome Database (LMPD)

LMPD ID
LMP008788
Gene ID
31376
Species
Drosophila melanogaster (Drosophila)
Gene Name
no receptor potential A
Gene Symbol
norpA
Synonyms
anon-EST:Posey221; CdkA; CG3620; DIP2; Dmel\CG3620; MRE18; nofC; NorpA; NORPA; PI-PLC; PLC; PLC-beta; PLCbeta; rof; x12; x13; x16; x24
Chromosome
X
Map Location
4B6-4C1

Proteins

no receptor potential A, isoform A
Refseq ID NP_525069
Protein GI 24639671
UniProt ID P13217
mRNA ID NM_080330
Length 1095
RefSeq Status REVIEWED
Protein sequence is identical to GI:281359824 (mRNA isoform)
no receptor potential A, isoform B
Refseq ID NP_726925
Protein GI 24639673
UniProt ID P13217
mRNA ID NM_167008
Length 1095
RefSeq Status REVIEWED
Protein sequence is identical to GI:281359824 (mRNA isoform)
no receptor potential A, isoform C
Refseq ID NP_001014721
Protein GI 62473465
UniProt ID X2JCI4
mRNA ID NM_001014721
Length 1095
RefSeq Status REVIEWED
Protein sequence is identical to GI:62473454 (mRNA isoform)
no receptor potential A, isoform D
Refseq ID NP_001014720
Protein GI 62473454
UniProt ID X2JCI4
mRNA ID NM_001014720
Length 1095
RefSeq Status REVIEWED
MTKKYEFDWIIPVPPELTTGCVFDRWFENEKETKENDFERDALFKVDEYGFFLYWKSEGRDGDVIELCQVSDIRAGGTPKDPKILDKVTKKNGTNIPELDKRSLTICSNTDYINITYHHVICPDAATAKIWLDGIRKITHNVKANNICPMMCLRKHWMRLSYCVEKSGKIPVKTLAKTFASGKTEKLVYTCIKDAGLPDDKNATMTKEQFTFDKFYALYHKVCPRNDIEELFTSITKGKQDFISLEQFIQFMNDKQRDPRMNEILYPLYEEKRCTEIINDYELDEEKKKNVQMSLDGFKRYLMSDENAPVFLDRLDFYMEMDQPLAHYYINSSHNTYLSGRQIGGKSSVEMYRQTLLAGCRCVELDCWNGKGEDEEPIVTHGHAYCTEILFKDCIQAIADCAFVSSEYPVILSFENHCNRAQQYKLAKYCDDFFGDLLLKEPLPDHPLDPGLPLPPPCKLKRKILIKNKRMKPEVEKVELELWLKGELKTDDDPEEDASAGKPPEAAAAPAPAPEAAAAAEGAAEGGGGAEAEAAAANYSGSTTNVHPWLSSMVNYAQPIKFQGFDKAIEKNIAHNMSSFAESAGMNYLKQSSIDFVNYNKRQMSRIYPKGTRADSSNYMPQVFWNAGCQMVSLNFQSSDLPMQLNQGKFEYNGGCGYLLKPDFMRRADKDFDPFADAPVDGVIAAQCSVKVIAGQFLSDKKVGTYVEVDMFGLPSDTVKKEFRTRLVANNGLNPVYNEDPFVFRKVVLPDLAVLRFGVYEESGKILGQRILPLDGLQAGYRHVSLRTEANFPMSLPMLFVNIELKIYVPDGFEDFMAMLSDPRGFAGAAKQQNEQMKALGIEEQSGGAARDAGKAKEEEKKEPPLVFEPVTLESLRQEKGFQKVGKKQIKELDTLRKKHAKERTSVQKTQNAAIDKLIKGKSKDDIRNDANIKNSINDQTKQWTDMIARHRKEEWDMLRQHVQDSQDAMKALMLTVQAAQIKQLEDRHARDIKDLNAKQAKMSADTAKEVQNDKTLKTKNEKDRRLREKRQNNVKRFMEEKKQIGVKQGRAMEKLKLAHSKQIEEFSTDVQKLMDMYKIEEEAYKTQGKTEFYA
no receptor potential A, isoform E
Refseq ID NP_001162661
Protein GI 281359824
UniProt ID P13217
mRNA ID NM_001169190
Length 1095
RefSeq Status REVIEWED
MTKKYEFDWIIPVPPELTTGCVFDRWFENEKETKENDFERDALFKVDEYGFFLYWKSEGRDGDVIELCQVSDIRAGGTPKDPKILDKVTKKNGTNIPELDKRSLTICSNTDYINITYHHVICPDAATAKSWQKNLRLITHNNRATNVCPRVNLMKHWMRLSYCVEKSGKIPVKTLAKTFASGKTEKLVYTCIKDAGLPDDKNATMTKEQFTFDKFYALYHKVCPRNDIEELFTSITKGKQDFISLEQFIQFMNDKQRDPRMNEILYPLYEEKRCTEIINDYELDEEKKKNVQMSLDGFKRYLMSDENAPVFLDRLDFYMEMDQPLAHYYINSSHNTYLSGRQIGGKSSVEMYRQTLLAGCRCVELDCWNGKGEDEEPIVTHGHAYCTEILFKDCIQAIADCAFVSSEYPVILSFENHCNRAQQYKLAKYCDDFFGDLLLKEPLPDHPLDPGLPLPPPCKLKRKILIKNKRMKPEVEKVELELWLKGELKTDDDPEEDASAGKPPEAAAAPAPAPEAAAAAEGAAEGGGGAEAEAAAANYSGSTTNVHPWLSSMVNYAQPIKFQGFDKAIEKNIAHNMSSFAESAGMNYLKQSSIDFVNYNKRQMSRIYPKGTRADSSNYMPQVFWNAGCQMVSLNFQSSDLPMQLNQGKFEYNGGCGYLLKPDFMRRADKDFDPFADAPVDGVIAAQCSVKVIAGQFLSDKKVGTYVEVDMFGLPSDTVKKEFRTRLVANNGLNPVYNEDPFVFRKVVLPDLAVLRFGVYEESGKILGQRILPLDGLQAGYRHVSLRTEANFPMSLPMLFVNIELKIYVPDGFEDFMAMLSDPRGFAGAAKQQNEQMKALGIEEQSGGAARDAGKAKEEEKKEPPLVFEPVTLESLRQEKGFQKVGKKQIKELDTLRKKHAKERTSVQKTQNAAIDKLIKGKSKDDIRNDANIKNSINDQTKQWTDMIARHRKEEWDMLRQHVQDSQDAMKALMLTVQAAQIKQLEDRHARDIKDLNAKQAKMSADTAKEVQNDKTLKTKNEKDRRLREKRQNNVKRFMEEKKQIGVKQGRAMEKLKLAHSKQIEEFSTDVQKLMDMYKIEEEAYKTQGKTEFYA
no receptor potential A, isoform F
Refseq ID NP_001284860
Protein GI 665389555
UniProt ID X2JCI4
mRNA ID NM_001297931
Length 1095
RefSeq Status REVIEWED
Protein sequence is identical to GI:62473454 (mRNA isoform)

Gene Information

Entrez Gene ID
31376
Gene Name
no receptor potential A
Gene Symbol
norpA
Species
Drosophila melanogaster

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005509 IEA:InterPro F calcium ion binding
GO:0004435 IEA:UniProtKB-EC F phosphatidylinositol phospholipase C activity
GO:0004871 IEA:UniProtKB-KW F signal transducer activity
GO:0035556 IEA:InterPro P intracellular signal transduction
GO:0016042 IEA:UniProtKB-KW P lipid catabolic process

Domain Information

InterPro Annotations

Accession Description
IPR000008 C2 domain
IPR011992 EF-hand domain pair
IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain
IPR016280 Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase beta
IPR009535 Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase beta, conserved site
IPR001192 Phosphoinositide phospholipase C family
IPR000909 Phospholipase C, phosphatidylinositol-specific , X domain
IPR001711 Phospholipase C, phosphatidylinositol-specific, Y domain
IPR015359 Phospholipase C, phosphoinositol-specific, EF-hand-like
IPR011993 Pleckstrin homology-like domain

UniProt Annotations

Entry Information

Gene Name
no receptor potential A
Protein Entry
PIPA_DROME
UniProt ID
X2JCI4
Species
Drosophila

Comments

Comment Type Description
Catalytic Activity 1-phosphatidyl-1D-myo-inositol 4,5- bisphosphate + H(2)O = 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol.
Similarity Contains 1 C2 domain.
Similarity Contains 1 PI-PLC X-box domain.
Similarity Contains 1 PI-PLC Y-box domain.
Similarity Contains C2 domain.
Similarity Contains Cdomain.
Similarity Contains PI-PLC X-box domain.
Similarity Contains PI-PLC Y-box domain.

Identical and Related Proteins

Unique RefSeq proteins for LMP008788 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
62473454 RefSeq NP_001014720 1095 no receptor potential A, isoform D
281359824 RefSeq NP_001162661 1095 no receptor potential A, isoform E

Identical Sequences to LMP008788 proteins

Reference Database Accession Length Protein Name
GI:281359824 GenBank ACL89372.1 1095 norpA-PA [synthetic construct]
GI:281359824 gnl FlyBase 1095 no receptor potential A, isoform B [Drosophila melanogaster]
GI:62473454 gnl FlyBase 1095 no receptor potential A, isoform C [Drosophila melanogaster]
GI:62473454 gnl FlyBase 1095 no receptor potential A, isoform D [Drosophila melanogaster]
GI:281359824 gnl FlyBase 1095 no receptor potential A, isoform E [Drosophila melanogaster]
GI:62473454 gnl FlyBase 1095 no receptor potential A, isoform F [Drosophila melanogaster]
GI:281359824 RefSeq NP_525069.2 1095 no receptor potential A, isoform A [Drosophila melanogaster]
GI:281359824 RefSeq NP_726925.1 1095 no receptor potential A, isoform B [Drosophila melanogaster]
GI:62473454 RefSeq NP_001014721.1 1095 no receptor potential A, isoform C [Drosophila melanogaster]
GI:62473454 RefSeq NP_001284860.1 1095 no receptor potential A, isoform F [Drosophila melanogaster]
GI:281359824 SwissProt P13217.4 1095 RecName: Full=1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; AltName: Full=No receptor potential A protein; AltName: Full=Phosphoinositide phospholipase C [Drosophila melanogaster]

Related Sequences to LMP008788 proteins

Reference Database Accession Length Protein Name
GI:281359824 GenBank AAA28724.1 1095 phospholipase C [Drosophila melanogaster]
GI:62473454 GenBank AAD55427.1 1095 norpA [Drosophila melanogaster]
GI:281359824 GenBank AAO25053.1 1095 GH28834p [Drosophila melanogaster]
GI:281359824 GenBank ABZ12194.1 1095 Sequence 6 from patent US 7309575
GI:62473454 GenBank EDW53178.1 1095 GM12340 [Drosophila sechellia]
GI:62473454 GenBank EDX01216.1 1095 GE16341 [Drosophila yakuba]
GI:281359824 gnl FlyBase 1095 no receptor potential A, isoform C [Drosophila melanogaster]
GI:281359824 gnl FlyBase 1095 no receptor potential A, isoform D [Drosophila melanogaster]
GI:281359824 gnl FlyBase 1095 no receptor potential A, isoform F [Drosophila melanogaster]
GI:62473454 RefSeq NP_525069.2 1095 no receptor potential A, isoform A [Drosophila melanogaster]
GI:62473454 RefSeq XP_002037019.1 1095 GM12340 [Drosophila sechellia]
GI:62473454 RefSeq XP_002100108.1 1095 GE16341 [Drosophila yakuba]