Gene/Proteome Database (LMPD)

LMPD ID
LMP008810
Gene ID
36669
Species
Drosophila melanogaster (Drosophila)
Gene Name
CG10253 gene product from transcript CG10253-RB
Gene Symbol
CG10253
Synonyms
dAGPS; Dmel\CG10253
Alternate Names
CG10253; CG10253-PA; CG10253-PB; CG10253-PC; CG10253-PD
Chromosome
2R
Map Location
51D3-51D3
EC Number
2.5.1.26

Proteins

CG10253, isoform A
Refseq ID NP_611006
Protein GI 24653753
UniProt ID Q9V778
mRNA ID NM_137162
Length 631
RefSeq Status REVIEWED
Protein sequence is identical to GI:320543969 (mRNA isoform)
CG10253, isoform B
Refseq ID NP_001188936
Protein GI 320543971
UniProt ID Q9V778
mRNA ID NM_001202007
Length 631
RefSeq Status REVIEWED
Protein sequence is identical to GI:320543969 (mRNA isoform)
CG10253, isoform C
Refseq ID NP_001188937
Protein GI 320543973
UniProt ID Q9V778
mRNA ID NM_001202008
Length 631
RefSeq Status REVIEWED
Protein sequence is identical to GI:320543969 (mRNA isoform)
CG10253, isoform D
Refseq ID NP_001188935
Protein GI 320543969
UniProt ID Q9V778
mRNA ID NM_001202006
Length 631
RefSeq Status REVIEWED
MAAKRNAVTTEAPESSAPGEGTALALDSRLSKRVESVIPKKRHEALKWFGWGYNDSQFYGKDGIICFRGEKYPLGGCELPSFTKWVEKKFDLRVDTTKQYPQLPRTYPRPVENAPFLHELKGTTQVDYSAEGIDRLVRCHGQTLNDIYSLWHHKFRRIPDLVVWPRCHDEVVQLVRLANKHNVMLVPFGGGTSVSGAITCPQNESRMICALDTSQMNRLLWLNRENLTVCFESGIVGQDLERVLRSEGLTVGHEPDSYEFSTLGGWVATRASGMKKNVYGNIEDLVVRVRMVTPSGTLERECSAPRVSCGPDFNHVILGSEGTLGVITEVVLKVRPLPSLRRYGSLAFPNFEQGVLFMREVARRRCQPASVRLMDNEQFMFGQALKPEKSWWASVVDAMKQRYVTSWKGIDLNQICAATLLFEGDLKDVQRQEALIYEIAEKFQGFPAGGQNGERGYILTFVIAYIRDFGLHQGIVAESFETSVPWDRCSLLCRSVKQRVVSECSKRSINYYTISCRVTQTYDAGACIYFYFGFRSTDVADPVELFEAIEHSARDEILSCGGSLSHHHGVGKIRSHWYRNAVTETGSSLYSAAKRHLDPKNIFALGNLLPLEEAQASPPPPTSSTPPKAKL

Gene Information

Entrez Gene ID
36669
Gene Name
CG10253 gene product from transcript CG10253-RB
Gene Symbol
CG10253
Species
Drosophila melanogaster

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005777 IDA:FlyBase C peroxisome
GO:0071949 ISS:UniProtKB F FAD binding
GO:0008762 IEA:InterPro F UDP-N-acetylmuramate dehydrogenase activity
GO:0008609 ISS:UniProtKB F alkylglycerone-phosphate synthase activity
GO:0008611 ISS:UniProtKB P ether lipid biosynthetic process

KEGG Pathway Links

KEGG Pathway ID Description
dme00565 Ether lipid metabolism
dme04146 Peroxisome

REACTOME Pathway Links

REACTOME Pathway ID Description
6226054 Plasmalogen biosynthesis

Domain Information

InterPro Annotations

Accession Description
IPR025650 Alkyldihydroxyacetonephosphate synthase
IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2
IPR006094 FAD linked oxidase, N-terminal
IPR016166 FAD-binding, type 2
IPR016167 FAD-binding, type 2, subdomain 1
IPR004113 FAD-linked oxidase, C-terminal
IPR016164 FAD-linked oxidase-like, C-terminal

UniProt Annotations

Entry Information

Gene Name
CG10253 gene product from transcript CG10253-RB
Protein Entry
ADAS_DROME
UniProt ID
Q9V778
Species
Drosophila

Comments

Comment Type Description
Catalytic Activity 1-acyl-glycerone 3-phosphate + a long-chain alcohol = an alkyl-glycerone 3-phosphate + a long-chain acid anion.
Cofactor Name=FAD; Xref=ChEBI:CHEBI:57692; Evidence={ECO:0000250};
Function Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids. {ECO:0000250}.
Pathway Glycerolipid metabolism; ether lipid biosynthesis.
Similarity Belongs to the FAD-binding oxidoreductase/transferase type 4 family. {ECO:0000305}.
Similarity Contains 1 FAD-binding PCMH-type domain. {ECO:0000255|PROSITE-ProRule:PRU00718}.
Subcellular Location Peroxisome {ECO:0000250}.
Subunit Homodimer. {ECO:0000250}.

Identical and Related Proteins

Unique RefSeq proteins for LMP008810 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
320543969 RefSeq NP_001188935 631 CG10253, isoform D

Identical Sequences to LMP008810 proteins

Reference Database Accession Length Protein Name
GI:320543969 gnl FlyBase 631 CG10253, isoform D [Drosophila melanogaster]
GI:320543969 gnl FlyBase 631 CG10253, isoform B [Drosophila melanogaster]
GI:320543969 gnl FlyBase 631 CG10253, isoform C [Drosophila melanogaster]
GI:320543969 RefSeq NP_611006.1 631 CG10253, isoform A [Drosophila melanogaster]
GI:320543969 RefSeq NP_001188936.1 631 CG10253, isoform B [Drosophila melanogaster]
GI:320543969 RefSeq NP_001188937.1 631 CG10253, isoform C [Drosophila melanogaster]

Related Sequences to LMP008810 proteins

Reference Database Accession Length Protein Name
GI:320543969 GenBank EDW47936.1 635 GM20165 [Drosophila sechellia]
GI:320543969 GenBank EDX07158.1 635 GD25643 [Drosophila simulans]
GI:320543969 GenBank ADG57801.1 659 MIP22246p, partial [Drosophila melanogaster]
GI:320543969 RefSeq XP_002033923.1 635 GM20165 [Drosophila sechellia]
GI:320543969 RefSeq XP_002091382.1 636 GE12271 [Drosophila yakuba]
GI:320543969 RefSeq XP_002081573.1 635 GD25643 [Drosophila simulans]