Gene/Proteome Database (LMPD)

LMPD ID
LMP008897
Gene ID
39520
Species
Drosophila melanogaster (Drosophila)
Gene Name
Actin binding protein 1
Gene Symbol
Abp1
Synonyms
CG10083; Dmel\CG10083
Alternate Names
Abp1-PA; CG10083-PA; Drebrin-like; actin binding protein 1
Chromosome
3L
Map Location
70B2-70B2

Proteins

actin binding protein 1
Refseq ID NP_648657
Protein GI 24663874
UniProt ID Q9VU84
mRNA ID NM_140400
Length 531
RefSeq Status REVIEWED
MAVSFEKNRAQIVAAWKDVLDDKSDTNWSLFGYEGQTNELKVVATGDGGVDELNEDLNSGKIMYAFVRIEDPKTGLNKYLLINWQGEGAPVLRKGTCANHIRDVSNLLSGAHLTINARNEDDIDLDRLLKKLSTVSSAYSFKEPRGAMEEQKAPVGTNYTRVIPTKELNASVMQDFWKKEEAEEKLRQEAEKESKRLELQKLEQEQRSREEKEHKEREKLVISTTKLQPAHVPIKTSPQPLSPEKTAPGFANNLTDAERMRQARNQEARELIGSRVGAAKAMFTKHTSEGQLQSKLNTQPPAKPARNSIAQRINVFNQNQPQDAPVPSPPRAASPAKPLPVEAPEPVVPAPAIAPAAPVAAEVVSTIAEVEESQPVDDLPLAHESEQFSTIKRSPHSKSNSLQSQSPDETTSSNETDTAVSQEQEEEVRTKVSVTVQQSQSVKSSGMSTLERNALTDLVNEDDFICQETLGDLGQRARALYDYQAADETEITFDPGDVITHIDQIDEGWWQGLGPDGTYGLFPANYVEIIN

Gene Information

Entrez Gene ID
39520
Gene Name
Actin binding protein 1
Gene Symbol
Abp1
Species
Drosophila melanogaster

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005737 IEA:UniProtKB-KW C cytoplasm
GO:0005856 IDA:UniProtKB C cytoskeleton
GO:0003779 IC:UniProtKB F actin binding
GO:0051015 IDA:FlyBase F actin filament binding
GO:0005547 IDA:FlyBase F phosphatidylinositol-3,4,5-trisphosphate binding
GO:0005546 IDA:FlyBase F phosphatidylinositol-4,5-bisphosphate binding
GO:0001786 IDA:FlyBase F phosphatidylserine binding
GO:0022416 IMP:FlyBase P chaeta development

REACTOME Pathway Links

REACTOME Pathway ID Description
6226198 Apoptosis
6226514 Apoptotic cleavage of cellular proteins
6226515 Apoptotic execution phase
6226516 Caspase-mediated cleavage of cytoskeletal proteins

Domain Information

InterPro Annotations

Accession Description
IPR002108 Actin-depolymerising factor homology domain
IPR029006 ADF-H/Gelsolin-like domain
IPR001452 SH3_domain

UniProt Annotations

Entry Information

Gene Name
Actin binding protein 1
Protein Entry
DBNL_DROME
UniProt ID
Q9VU84
Species
Drosophila

Comments

Comment Type Description
Function Actin-binding adapter protein. Binds to F-actin but is not involved in actin polymerization, capping or bundling. Does not bind G-actin (By similarity). Does not seem to be involved in actin-based lamella protrusion during cell migration. {ECO:0000250, ECO:0000269|PubMed:12975351}.
Similarity Belongs to the ABP1 family. {ECO:0000305}.
Similarity Contains 1 ADF-H domain. {ECO:0000255|PROSITE- ProRule:PRU00599}.
Similarity Contains 1 SH3 domain. {ECO:0000255|PROSITE- ProRule:PRU00192}.
Subcellular Location Cytoplasm, cytoskeleton {ECO:0000250}.

Identical and Related Proteins

Unique RefSeq proteins for LMP008897 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
24663874 RefSeq NP_648657 531 actin binding protein 1

Identical Sequences to LMP008897 proteins

Reference Database Accession Length Protein Name
GI:24663874 GenBank AAX33537.1 531 LD21091p [Drosophila melanogaster]
GI:24663874 gnl FlyBase 531 actin binding protein 1 [Drosophila melanogaster]
GI:24663874 SwissProt Q9VU84.1 531 RecName: Full=Drebrin-like protein; AltName: Full=Actin binding protein 1 [Drosophila melanogaster]

Related Sequences to LMP008897 proteins

Reference Database Accession Length Protein Name
GI:24663874 GenBank EDW41398.1 531 GM24586 [Drosophila sechellia]
GI:24663874 GenBank EDW94425.1 531 GE20057 [Drosophila yakuba]
GI:24663874 GenBank EDX10370.1 531 GD12654 [Drosophila simulans]
GI:24663874 RefSeq XP_002030412.1 531 GM24586 [Drosophila sechellia]
GI:24663874 RefSeq XP_002094713.1 531 GE20057 [Drosophila yakuba]
GI:24663874 RefSeq XP_002084785.1 531 GD12654 [Drosophila simulans]