Gene/Proteome Database (LMPD)

LMPD ID
LMP008899
Gene ID
35540
Species
Drosophila melanogaster (Drosophila)
Gene Name
Ecdysone receptor
Gene Symbol
EcR
Synonyms
anon-WO0229075.1; CG1765; CG8347; dECR; DEcR; Dhr23; dmEcR; DmEcR; Dmel\CG1765; EcdR; ecr; Ecr; ECR; EcR-A; EcR-B; EcR-B1; ECR-C; Ecr1B; EcR1b; EcRA; EcRB-1; EcRB1; EcRC; lie; ms(2)06410; ms(2)42A; NR1H1; snt
Chromosome
2R
Map Location
42A9-42A12

Proteins

ecdysone receptor, isoform A
Refseq ID NP_724456
Protein GI 24585962
UniProt ID P34021
mRNA ID NM_165461
Length 849
RefSeq Status REVIEWED
MLTTSGQQQSKQKLSTLPSHILLQQQLAASAGPSSSVSLSPSSSAALTLHVASANGGARETTSAAAVKDKLRPTPTAIKIEPMPDVISVGTVAGGSSVATVVAPAATTTSNKPNSTAAPSTSAAAANGHLVLVPNKRPRLDVTEDWMSTPSPGSVPSSAPPLSPSPGSQNHSYNMSNGYASPMSAGSYDPYSPTGKTGRDDLSPSSSLNGYSANESCDAKKSKKGPAPRVQEELCLVCGDRASGYHYNALTCEGCKGFFRRSVTKSAVYCCKFGRACEMDMYMRRKCQECRLKKCLAVGMRPECVVPENQCAMKRREKKAQKEKDKMTTSPSSQHGGNGSLASGGGQDFVKKEILDLMTCEPPQHATIPLLPDEILAKCQARNIPSLTYNQLAVIYKLIWYQDGYEQPSEEDLRRIMSQPDENESQTDVSFRHITEITILTVQLIVEFAKGLPAFTKIPQEDQITLLKACSSEVMMLRMARRYDHSSDSIFFANNRSYTRDSYKMAGMADNIEDLLHFCRQMFSMKVDNVEYALLTAIVIFSDRPGLEKAQLVEAIQSYYIDTLRIYILNRHCGDSMSLVFYAKLLSILTELRTLGNQNAEMCFSLKLKNRKLPKFLEEIWDVHAIPPSVQSHLQITQEENERLERAERMRASVGGAITAGIDCDSASTSAAAAAAQHQPQPQPQPQPSSLTQNDSQHQTQPQLQPQLPPQLQGQLQPQLQPQLQTQLQPQIQPQPQLLPVSAPVPASVTAPGSLSAVSTSSEYMGGSAAIGPITPATTSSITAAVTASSTTSAVPMGNGVGVGVGVGGNVSMYANAQTAMALMGVALHSHQEQLIGGVAVKSEHSTTA
ecdysone receptor, isoform B
Refseq ID NP_724460
Protein GI 24585970
UniProt ID P34021
mRNA ID NM_165465
Length 878
RefSeq Status REVIEWED
Protein sequence is identical to GI:281360198 (mRNA isoform)
ecdysone receptor, isoform C
Refseq ID NP_724459
Protein GI 24585968
UniProt ID P34021
mRNA ID NM_165464
Length 669
RefSeq Status REVIEWED
MDTCGLVAELAHYIDAYGRDDLSPSSSLNGYSANESCDAKKSKKGPAPRVQEELCLVCGDRASGYHYNALTCEGCKGFFRRSVTKSAVYCCKFGRACEMDMYMRRKCQECRLKKCLAVGMRPECVVPENQCAMKRREKKAQKEKDKMTTSPSSQHGGNGSLASGGGQDFVKKEILDLMTCEPPQHATIPLLPDEILAKCQARNIPSLTYNQLAVIYKLIWYQDGYEQPSEEDLRRIMSQPDENESQTDVSFRHITEITILTVQLIVEFAKGLPAFTKIPQEDQITLLKACSSEVMMLRMARRYDHSSDSIFFANNRSYTRDSYKMAGMADNIEDLLHFCRQMFSMKVDNVEYALLTAIVIFSDRPGLEKAQLVEAIQSYYIDTLRIYILNRHCGDSMSLVFYAKLLSILTELRTLGNQNAEMCFSLKLKNRKLPKFLEEIWDVHAIPPSVQSHLQITQEENERLERAERMRASVGGAITAGIDCDSASTSAAAAAAQHQPQPQPQPQPSSLTQNDSQHQTQPQLQPQLPPQLQGQLQPQLQPQLQTQLQPQIQPQPQLLPVSAPVPASVTAPGSLSAVSTSSEYMGGSAAIGPITPATTSSITAAVTASSTTSAVPMGNGVGVGVGVGGNVSMYANAQTAMALMGVALHSHQEQLIGGVAVKSEHSTTA
ecdysone receptor, isoform D
Refseq ID NP_724457
Protein GI 24585964
UniProt ID P34021
mRNA ID NM_165462
Length 849
RefSeq Status REVIEWED
Protein sequence is identical to GI:24585962 (mRNA isoform)
ecdysone receptor, isoform E
Refseq ID NP_724458
Protein GI 24585966
UniProt ID P34021
mRNA ID NM_165463
Length 849
RefSeq Status REVIEWED
Protein sequence is identical to GI:24585962 (mRNA isoform)
ecdysone receptor, isoform G
Refseq ID NP_001163061
Protein GI 281360198
UniProt ID P34021
mRNA ID NM_001169590
Length 878
RefSeq Status REVIEWED
MKRRWSNNGGFMRLPEESSSEVTSSSNGLVLPSGVNMSPSSLDSHDYCDQDLWLCGNESGSFGGSNGHGLSNSVITLAMHGCSSTLPAQTTIIPINGNANGNGGSTNGQYVPGATNLGALANGMLNGGFNGMQQQIQNGHGLINSTTPSTPTTPLHLQQNLGGAGGGGIGGMGILHHANGTPNGLIGVVGGGGGVGLGVGGGGVGGLGMQHTPRSDSVNSISSGRDDLSPSSSLNGYSANESCDAKKSKKGPAPRVQEELCLVCGDRASGYHYNALTCEGCKGFFRRSVTKSAVYCCKFGRACEMDMYMRRKCQECRLKKCLAVGMRPECVVPENQCAMKRREKKAQKEKDKMTTSPSSQHGGNGSLASGGGQDFVKKEILDLMTCEPPQHATIPLLPDEILAKCQARNIPSLTYNQLAVIYKLIWYQDGYEQPSEEDLRRIMSQPDENESQTDVSFRHITEITILTVQLIVEFAKGLPAFTKIPQEDQITLLKACSSEVMMLRMARRYDHSSDSIFFANNRSYTRDSYKMAGMADNIEDLLHFCRQMFSMKVDNVEYALLTAIVIFSDRPGLEKAQLVEAIQSYYIDTLRIYILNRHCGDSMSLVFYAKLLSILTELRTLGNQNAEMCFSLKLKNRKLPKFLEEIWDVHAIPPSVQSHLQITQEENERLERAERMRASVGGAITAGIDCDSASTSAAAAAAQHQPQPQPQPQPSSLTQNDSQHQTQPQLQPQLPPQLQGQLQPQLQPQLQTQLQPQIQPQPQLLPVSAPVPASVTAPGSLSAVSTSSEYMGGSAAIGPITPATTSSITAAVTASSTTSAVPMGNGVGVGVGVGGNVSMYANAQTAMALMGVALHSHQEQLIGGVAVKSEHSTTA

Gene Information

Entrez Gene ID
35540
Gene Name
Ecdysone receptor
Gene Symbol
EcR
Species
Drosophila melanogaster

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005634 IEA:UniProtKB-KW C nucleus
GO:0004884 IEA:InterPro F ecdysteroid hormone receptor activity
GO:0043565 IEA:InterPro F sequence-specific DNA binding
GO:0005496 IEA:InterPro F steroid binding
GO:0008270 IEA:InterPro F zinc ion binding

Domain Information

InterPro Annotations

Accession Description
IPR003069 Ecdystd_rcpt
IPR008946 Nuclear hormone receptor, ligand-binding
IPR000536 Nuclear hormone receptor, ligand-binding, core
IPR001723 Steroid hormone receptor
IPR013088 Zinc finger, NHR/GATA-type
IPR001628 Zinc finger, nuclear hormone receptor-type

UniProt Annotations

Entry Information

Gene Name
Ecdysone receptor
Protein Entry
ECR_DROME
UniProt ID
P34021
Species
Drosophila

Comments

Comment Type Description
Similarity Belongs to the nuclear hormone receptor family.
Similarity Contains nuclear receptor DNA-binding domain.

Identical and Related Proteins

Unique RefSeq proteins for LMP008899 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
24585962 RefSeq NP_724456 849 ecdysone receptor, isoform A
24585968 RefSeq NP_724459 669 ecdysone receptor, isoform C
281360198 RefSeq NP_001163061 878 ecdysone receptor, isoform G

Identical Sequences to LMP008899 proteins

Reference Database Accession Length Protein Name
GI:281360198 GenBank AAS93740.1 878 RE33854p [Drosophila melanogaster]
GI:281360198 GenBank AAT94463.1 878 RE06878p [Drosophila melanogaster]
GI:281360198 GenBank ABT01315.1 878 Sequence 75 from patent US 7208589
GI:281360198 GenBank ADF18292.1 878 Sequence 75 from patent US 7667019
GI:281360198 GenBank AIB01804.1 878 Sequence 32 from patent US 8669051
GI:24585962 gnl FlyBase 849 ecdysone receptor, isoform A [Drosophila melanogaster]
GI:24585962 gnl FlyBase 849 ecdysone receptor, isoform D [Drosophila melanogaster]
GI:24585962 gnl FlyBase 849 ecdysone receptor, isoform E [Drosophila melanogaster]
GI:24585968 gnl FlyBase 669 ecdysone receptor, isoform C [Drosophila melanogaster]
GI:281360198 gnl FlyBase 878 ecdysone receptor, isoform G [Drosophila melanogaster]
GI:24585962 RefSeq NP_724457.1 849 ecdysone receptor, isoform D [Drosophila melanogaster]
GI:24585962 RefSeq NP_724458.1 849 ecdysone receptor, isoform E [Drosophila melanogaster]

Related Sequences to LMP008899 proteins

Reference Database Accession Length Protein Name
GI:24585962 GenBank AAA28498.1 878 ecdysone receptor [Drosophila melanogaster]
GI:24585962 GenBank AAL68274.1 872 RE16656p [Drosophila melanogaster]
GI:281360198 GenBank AAM58464.1 878 Sequence 15 from patent US 6379945
GI:281360198 GenBank AAR47344.1 878 Sequence 8 from patent US 6610828
GI:24585962 GenBank AAS93740.1 878 RE33854p [Drosophila melanogaster]
GI:281360198 GenBank ABP08262.1 878 Sequence 8 from patent US 7183061
GI:24585962 GenBank EDV59837.1 854 GG10830 [Drosophila erecta]
GI:281360198 GenBank EDW49564.1 884 GM16480 [Drosophila sechellia]
GI:24585968 gnl FlyBase 849 ecdysone receptor, isoform A [Drosophila melanogaster]
GI:24585968 gnl FlyBase 849 ecdysone receptor, isoform D [Drosophila melanogaster]
GI:24585968 gnl FlyBase 849 ecdysone receptor, isoform E [Drosophila melanogaster]
GI:24585968 RefSeq NP_724456.1 849 ecdysone receptor, isoform A [Drosophila melanogaster]
GI:24585968 RefSeq NP_724457.1 849 ecdysone receptor, isoform D [Drosophila melanogaster]
GI:24585968 RefSeq NP_724458.1 849 ecdysone receptor, isoform E [Drosophila melanogaster]
GI:24585962 RefSeq XP_001970778.1 854 GG10830 [Drosophila erecta]
GI:281360198 RefSeq XP_002043398.1 884 GM16480 [Drosophila sechellia]
GI:281360198 RefSeq XP_002080271.1 882 GD10334 [Drosophila simulans]
GI:24585962 SwissProt P34021.1 878 RecName: Full=Ecdysone receptor; AltName: Full=20-hydroxy-ecdysone receptor; Short=20E receptor; AltName: Full=EcRH; AltName: Full=Ecdysteroid receptor; AltName: Full=Nuclear receptor subfamily 1 group H member 1 [Drosophila melanogaster]