Gene/Proteome Database (LMPD)

LMPD ID
LMP008901
Gene ID
31157
Species
Drosophila melanogaster (Drosophila)
Gene Name
Oculocerebrorenal syndrome of Lowe ortholog (H. sapiens)
Gene Symbol
Ocrl
Synonyms
CG3573; Dmel\CG3573; dOCRL; EG:86E4.5
Chromosome
X
Map Location
2B16-2B16

Proteins

oculocerebrorenal syndrome of lowe ortholog, isoform A
Refseq ID NP_569962
Protein GI 24639220
UniProt ID O46094
mRNA ID NM_130606
Length 850
RefSeq Status REVIEWED
Protein sequence is identical to GI:442614833 (mRNA isoform)
oculocerebrorenal syndrome of lowe ortholog, isoform B
Refseq ID NP_001259153
Protein GI 442614833
UniProt ID O46094
mRNA ID NM_001272224
Length 850
RefSeq Status REVIEWED
MDTLSEAVANGTATAATRTTKDIVKERFKEDETIEYIFEAYQIKGPEYSNRLLALVSSQSGGTFAIIAFSYLRTPLSSANELIINKVFAIDHNFQLRQDSKSSITTQQFDLSTAEDGPIKYYYYATESHHYEEFVAKVISFKSTMAQHDPETVLNFRWLNDYRQIGEVKQELKKRESEYIVYKDIIIYCATWNVNNKTCSDSNNPLRAWLACSEKPPDIYAIGLQELDTPTKAMLNSTQVQAIEKQWIDKMMDSVHPDVEYEILMSHRLVATMLTVIVRKQLRQHIIRCRPKSVARGIFNTLGNKGGVAISLQLNEGNICFVNSHLAAHMGYVEERNQDYNAIVEGIRFDDGRTISDHDHIFWVGDLNYRIQEPPGQQRPGPLSDAQTYELLLQYDQLRQEMRRGKCFEGYTEGEIKFRPTYKYDPGTDNYDSSEKQRAPAYCDRVLWKGTRIEQLAYNSIMEIRQSDHKPVYAVFQVKVKTRDEVKYKRVQEEVLKAVDKRENDNQPQINVEKTVIDFGTVRFNEPSTRDFNVYNNCPLPVDFSFKEKDIHAICEPWLHVDPRQDSLLIDSARSIRLKMNANVRTIAGLLRKIRASDNFDILILHVENGRDIFITVTGDYQPSCFGLSMETMCRTDRPLSEYSQDQIKQLMNDESPEYRVTMPREFFLLIDYLYRQGSKQVGAFPSYDSRLSLGAQFNSVRDWLDTWSDDPFPANAETAAQALLLLLDLPEHALLEPVVENLLECTNKSQAMDYISLLSPPKRNVFMHLCMFLRAGIESQFYDLHQVASTFGRILLRSTERAAWMDYHSRCIQFMRLFIDTDVEAMGNGNEGAGTGTGSGSGTRAGLQA

Gene Information

Entrez Gene ID
31157
Gene Name
Oculocerebrorenal syndrome of Lowe ortholog (H. sapiens)
Gene Symbol
Ocrl
Species
Drosophila melanogaster

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005737 IDA:FlyBase C cytoplasm
GO:0005769 IDA:FlyBase C early endosome
GO:0005770 IDA:FlyBase C late endosome
GO:0055037 IDA:FlyBase C recycling endosome
GO:0052659 IEA:UniProtKB-EC F inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity
GO:0052658 IEA:UniProtKB-EC F inositol-1,4,5-trisphosphate 5-phosphatase activity
GO:0004445 IEA:UniProtKB-EC F inositol-polyphosphate 5-phosphatase activity
GO:0034593 IMP:FlyBase F phosphatidylinositol bisphosphate phosphatase activity
GO:0032187 IMP:FlyBase P actomyosin contractile ring localization
GO:0006897 IMP:FlyBase P endocytosis
GO:0046856 IMP:FlyBase P phosphatidylinositol dephosphorylation
GO:2000431 IMP:FlyBase P regulation of cytokinesis, actomyosin contractile ring assembly
GO:0007165 IEA:InterPro P signal transduction

Domain Information

InterPro Annotations

Accession Description
IPR005135 Endonuclease/exonuclease/phosphatase
IPR000300 Inositol polyphosphate-related phosphatase
IPR008936 Rho GTPase activation protein
IPR000198 Rho GTPase-activating protein domain

UniProt Annotations

Entry Information

Gene Name
Oculocerebrorenal syndrome of Lowe ortholog (H. sapiens)
Protein Entry
O46094_DROME
UniProt ID
O46094
Species
Drosophila

Identical and Related Proteins

Unique RefSeq proteins for LMP008901 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
442614833 RefSeq NP_001259153 850 oculocerebrorenal syndrome of lowe ortholog, isoform B

Identical Sequences to LMP008901 proteins

Reference Database Accession Length Protein Name
GI:442614833 EMBL CAA15931.1 850 EG:86E4.5 [Drosophila melanogaster]
GI:442614833 GenBank AAV36976.1 850 LD39196p [Drosophila melanogaster]
GI:442614833 GenBank ACL88496.1 850 CG3573-PA, partial [synthetic construct]
GI:442614833 gnl FlyBase 850 oculocerebrorenal syndrome of lowe ortholog, isoform A [Drosophila melanogaster]
GI:442614833 gnl FlyBase 850 oculocerebrorenal syndrome of lowe ortholog, isoform B [Drosophila melanogaster]
GI:442614833 RefSeq NP_569962.2 850 oculocerebrorenal syndrome of lowe ortholog, isoform A [Drosophila melanogaster]

Related Sequences to LMP008901 proteins

Reference Database Accession Length Protein Name
GI:442614833 GenBank AAL29114.1 521 LP11751p [Drosophila melanogaster]
GI:442614833 GenBank JAC40098.1 909 Type II inositol 1,4,5-trisphosphate 5-phosphatase [Bactrocera dorsalis]
GI:442614833 GenBank JAC40099.1 909 Type II inositol 1,4,5-trisphosphate 5-phosphatase [Bactrocera dorsalis]
GI:442614833 GenBank JAD08814.1 914 hypothetical protein g.38092 [Bactrocera cucurbitae]
GI:442614833 gnl WGS:AADE 844 GA17531 [Drosophila pseudoobscura pseudoobscura]
GI:442614833 RefSeq XP_001354524.2 844 GA17531 [Drosophila pseudoobscura pseudoobscura]